ID A0A0P7V4S4_SCLFO Unreviewed; 1342 AA.
AC A0A0P7V4S4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Intron-binding protein aquarius-like {ECO:0000313|EMBL:KPP67951.1};
GN ORFNames=Z043_113408 {ECO:0000313|EMBL:KPP67951.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP67951.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP67951.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP67951.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR038901}.
CC -!- SIMILARITY: Belongs to the CWF11 family.
CC {ECO:0000256|PIRNR:PIRNR038901}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP67951.1}.
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DR EMBL; JARO02004762; KPP67951.1; -; Genomic_DNA.
DR STRING; 113540.ENSSFOP00015075025; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd17935; EEXXQc_AQR; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR048966; Aquarius_b-barrel.
DR InterPro; IPR048967; Aquarius_insert.
DR InterPro; IPR032174; Aquarius_N.
DR InterPro; IPR026300; CWF11_fam.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF5; RNA HELICASE AQUARIUS; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF16399; Aquarius_N_1st; 1.
DR Pfam; PF21143; Aquarius_N_2nd; 1.
DR Pfam; PF21144; Aquarius_N_3rd; 1.
DR PIRSF; PIRSF038901; AQR_cwf11; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|PIRNR:PIRNR038901};
KW mRNA splicing {ECO:0000256|PIRNR:PIRNR038901};
KW Nucleus {ECO:0000256|PIRNR:PIRNR038901};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805}.
FT DOMAIN 2..359
FT /note="RNA helicase aquarius N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16399"
FT DOMAIN 442..608
FT /note="RNA helicase aquarius beta-barrel"
FT /evidence="ECO:0000259|Pfam:PF21143"
FT DOMAIN 656..743
FT /note="RNA helicase aquarius insertion"
FT /evidence="ECO:0000259|Pfam:PF21144"
FT DOMAIN 786..957
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1005..1195
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 1273..1342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1273..1311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1313..1333
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1342 AA; 156002 MW; C53C389B0996BAF2 CRC64;
MRLANKYWAP HVKNKLPFDA KVMEDIYQSE ILKSKFAIRK IMLLEFSQYL ENYLWVNYTP
EVSNNAYLMS ICCIVNEKFR ENVPAWEVFK KKPQHFPYFF KCVMEMSLAG AKSNLSLKEQ
TILLLFLDHC FNSLEVDLIR EQVQQLISLP MWICLLPARL QHELKKVPKL QKFWNLIKKN
YEKMDKKDSD QADRERTFLS LLIKKFLVVL SSILPSGDVS MEKVHYCERF LELMIDLEAL
LPTRRWFNTV LDDSHFVVYC HLSGLPLREK EGHLFCQLLD MLKFYTGFEI NDQTGNALTE
NEMTTLHYDR ITSLQRAAFA HFPELQDFAL SNVAAVDTRE SLIKHFGLLS PNTLHKVSRH
ERRISQIEQL NQMPLYPTEK IIWDENIVPT EYYSGEGCLA LPKLNLQFLT LHDYLLRNFN
LFRLESTYEI RQDIEDVVSR MKPWQSEYGG VVFGGWARMA QTILSFSIVE VAKPNIGENW
PARVRADVTI NLNVRDQIKS EWEGLRKHDV CFLITVRPTL PYGTRFDRRQ PFLEQMGLVY
VRGCEVQGML DDKGRVIEEG PEPKPKLRGD TRTFRVWLDP NQYQQDMTNT IQNGTEDPYE
TFNIIMRRKP KENNFKAVLE TIRNLMNTEC VVPDWLHDII LGYGDPGSAH YSKMPNQIST
LDFNDTFLSI DHLKASFPGY KVKVTEENPS LQIPPFRIKF PLKNVKGKKR NADEEDGESR
EGDNTLVVEP HVIPNRGPYP YNQPKRSFSK ENFENDYRAD VNMEAVVTGH EQPCQKQCVP
FHSPHVVGPP GTGKTDVAVQ IISNLYHNFP EQRTLIVTHS NQALNQLFEK IMALDIDERH
LLRLGHGEEE LETEKDFSRY GRVNYVLARR LELLREVARL QESLDVPGDV SYTCETAGHF
YLYQVMSRWE EYMSKVKPKH GRNEFRAFEL LRSGLDRSKY LLVKEAKIIA MTCTHAALKR
HDLVELGFKN PEDGFSRLKR WIMIGDHHQL PPVIKNMAFQ KYSNMEQSLF TRCVRLGVPT
VDLDAQGRAR ASLCNLYNWR YKRLGNLPHV QLQPEFRAPN PGLTFDFQLI NVEDFNGVGE
SEPNPYFYQN LAEAEYAVAL FMYMRLLGYP AEKISILTTY NGQKHLIRDV INQRCASNPY
FGHPSKVTTV DRFQGQQNDY IILSLVRTKA VGHLRDVRRL VVAMSRARLG LYIFARVSLF
QNCFELTPVF NQLTARPLQL HIRPHEYYTL DLSEKRPEHP DQVVNNMPEM ANLVYTMYMN
LIQNAQNRQV QLLPPPSQEQ AAADAESEQS QLEQMAEEPS TEQAPQDTPM EQQEENQEER
PRMPEHPGRD SDSEDSGAEE DA
//
