ID A0A0P7VBF2_SCLFO Unreviewed; 1022 AA.
AC A0A0P7VBF2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0000259|PROSITE:PS50261};
GN ORFNames=Z043_110704 {ECO:0000313|EMBL:KPP70466.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP70466.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP70466.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP70466.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP70466.1}.
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DR EMBL; JARO02003453; KPP70466.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7VBF2; -.
DR STRING; 113540.ENSSFOP00015018998; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF264; ADHESION G-PROTEIN COUPLED RECEPTOR G2; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 712..735
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 747..767
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 773..797
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 817..839
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 867..896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 917..936
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 942..965
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 710..966
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1022 AA; 112811 MW; 3B2D0922A2DB6E87 CRC64;
MTRFRTRGQR LDPSQGFLET DRTGRAPHGS HMPHRERVSS GARNGARSAT PRAAPRMVSF
PGQDLKSKGH NLLQSKVFLC LSILLCHEAI VTEAAYLGGM KAVFPNDCGD HWTLREQGTL
AKLAKMTVCV DVRVLFPGTW IAFSYRSPHS PQSELTLQGD GRILLVMLGW QRYRFYVPLA
LNQWHRVCLS LNAPKSFLTL RVNNVNYWQS IGTAVSPTSS SGELRLGCQR PSESVAKVEL
YLLRVWDNVL RHSNCEDGNV VGWNSEQWEY HASTVMEDST LPCAAFYWMD LEVNVTGVQN
ESDITVEAIK VMCDTKENIS LTRCSVLLQL SNAVSTCRLV QVLKTTAGNI QTNLLGSVQS
VAQGHCPNSM TSPPAGDIVM CDTPTLVSSP CQYSGLVNVT CNSYAETVYV PLMTNTPGNV
TCPSPSSSGT TVSVEEELAG LLASTSDVLA LNSSEVEMLV SKLQQLLSGP NVSLAVGNTT
IAIVSNLLNA SASVLAASST RLIEVVDTVG LKLVLTNGIQ TIQSPSLALA VKKMNGTNFQ
QTSFTILDPN NIQVSGEAKL GRSVLPQASI TLPASLTSNL TPEEQLQASR VQFNFYQKST
LFVDPSLGNR TLNSGILGSS VSNLTISGLK DNVVFTLRNN EPIPANFVAS CVFWDFSRNG
GQGGWNSAGC FIQNSTDEET ICSCNHLTSF GVLLDISMQG ITDPTQILIL TYITYIGCGI
SAIFLSVTLL TYLAFEKLRK DIPSKILINL CLALLLLNLV FLLDSWLALY SHAVGLCIST
AFFLHYFLLA SFTWMGLEAF HMYLALVKVF NTYVPRYMLK FGLVGWGVPL IVVIIVIAIN
KDNYGLMSYG RFPDGSTDDF CWIKNNVAFY VAVVAYFCLI FLLNMAMFVV VLVQLCRIKR
QNPHNTQHRN VWQEMRSVAG LTFLLGLTWG FAFFAWGPVN LAFMYLFCIF NCLQGFFIFV
FHCAVKDVVR RQWRTYLCCG KLWLPENSGN PVEDAVITAM EQPSEDVVLN EINSRHRHQR
EH
//
