ID A0A0P7VEH9_SCLFO Unreviewed; 691 AA.
AC A0A0P7VEH9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Fibronectin type-III domain-containing protein {ECO:0000259|PROSITE:PS50853};
GN ORFNames=Z043_107113 {ECO:0000313|EMBL:KPP73779.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP73779.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP73779.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP73779.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC {ECO:0000256|ARBA:ARBA00004246}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004162}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004162}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004586}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP73779.1}.
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DR EMBL; JARO02002027; KPP73779.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7VEH9; -.
DR STRING; 113540.ENSSFOP00015003605; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF29; LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT1; 1.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF01462; LRRNT; 1.
DR SMART; SM00364; LRR_BAC; 4.
DR SMART; SM00369; LRR_TYP; 8.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS51450; LRR; 3.
PE 4: Predicted;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..691
FT /note="Fibronectin type-III domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006143677"
FT TRANSMEM 555..581
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 435..529
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 664..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 691 AA; 76027 MW; AC6CA42ADC0BCFF8 CRC64;
MALEGVSELR DWLFLLLLCL TLFAEMLEFA AAMAVARGAG SEIDVTCPAA CRCDEDFIYC
NDRGLTAIPP LPFAATILYL QNNHIDNAGL PTSLEKHLTV QVVYLYDNEL DDFPMHLPPS
LRELHLQDNN IRTLPRSALA RLPLLEKLHL DDNSISTVSI EDQAFADNPR LRLLFLSRNH
LSSIPSGLPA SLEELRLDDN RISTIPTHAF RGLSSLRRLV LDGNLLANQR IADDTFSRLT
NLTELSLVRN SLQTPPFNLP SIHLQRLNLQ DNALIHMPRG SLDGMRRLQR LDLSGNNLTT
LPRGLFRDLD SLAQLLARGN PWHCGCNLRW VHDWLHARGS TITVRGFICQ NPERVRGLAL
QDLSSQMEEC ESSPAGAGAV GAGSRDLGNG EKAIATSTTL SPPQGSLFTL RSKRPGLRFP
DSGLDYSLGS SANSKTLVLN VKPLSPHSIH LTWRVPQPSA SFRLSWLRLG NGAAMGSITE
TLVPGDRREY LLNALQPQSS YIICMAPLPA DTRSAVLEGN GDPDETPVCA RAETADLSQP
SSEKGENRGP EQLSVLSLAG IIGGATALVF LALIFAIVCW CGHRTRHISD REHSTRSSYR
SNKRYDDYVE SGTKKDTSIL EIRGPGFQMT PMAAQQPLHT KALREDYIIH TIFPSNGTGL
YKGTQNTNNS GFGTNRGHRE GGIPDIDYSY T
//
