ID A0A0P7VTB3_SCLFO Unreviewed; 360 AA.
AC A0A0P7VTB3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE RecName: Full=Snurportin-1 {ECO:0000256|ARBA:ARBA00016034, ECO:0000256|PIRNR:PIRNR037955};
DE AltName: Full=RNA U transporter 1 {ECO:0000256|ARBA:ARBA00031454, ECO:0000256|PIRNR:PIRNR037955};
GN ORFNames=Z043_100628 {ECO:0000313|EMBL:KPP79767.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP79767.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP79767.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP79767.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Functions as an U snRNP-specific nuclear import adapter.
CC Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import
CC of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
CC {ECO:0000256|ARBA:ARBA00003975, ECO:0000256|PIRNR:PIRNR037955}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR037955}.
CC -!- SIMILARITY: Belongs to the snurportin family.
CC {ECO:0000256|ARBA:ARBA00007540, ECO:0000256|PIRNR:PIRNR037955}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP79767.1}.
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DR EMBL; JARO02000130; KPP79767.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7VTB3; -.
DR STRING; 113540.ENSSFOP00015034967; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006606; P:protein import into nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0061015; P:snRNA import into nucleus; IEA:UniProtKB-UniRule.
DR CDD; cd09232; Snurportin-1_C; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR017336; Snurportin-1.
DR InterPro; IPR024721; Snurportin-1_N.
DR InterPro; IPR047857; Snurportin1_C.
DR PANTHER; PTHR13403:SF6; SNURPORTIN-1; 1.
DR PANTHER; PTHR13403; SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1; 1.
DR Pfam; PF11538; Snurportin1; 1.
DR PIRSF; PIRSF037955; Snurportin-1; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR037955};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PIRNR:PIRNR037955};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037955}.
FT DOMAIN 18..80
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REGION 75..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT SITE 115
FT /note="Interaction with m3G-cap structure"
FT /evidence="ECO:0000256|PIRSR:PIRSR037955-1"
FT SITE 154
FT /note="Interaction with m3G-cap structure"
FT /evidence="ECO:0000256|PIRSR:PIRSR037955-1"
FT SITE 287
FT /note="Interaction with m3G-cap structure"
FT /evidence="ECO:0000256|PIRSR:PIRSR037955-1"
SQ SEQUENCE 360 AA; 41060 MW; E947B821E953F42A CRC64;
MSDPVFAMDD LSEALGASFS VSQEPNSTSA PHPRLAQYKS KYSVLEQGER RRRFLELQKT
KRLNYVNHAR RLADGDWTGA DSDEEQGKED EEDQGMEIEQ RRKLPKHYAN QLMLSEWLVD
VPSDLDGSWL MVVCPVGKRS LIVASRGSTA AYTKSGYCVN RFPSLLPGGN KHNSATGKDY
TILDCIYSEL DRTYYILDVM CWRGHPVYDC PTEFRFYWLH SKVQETDGLS EIARRNPFRF
MSLQSVNCTP QSIREALSAE YSFKVDGLLF YHRQTHYTPG STPLVGWLRP YMVSDILGME
VPECSLTAKP AYAGHQMQQI LEHKKISTEV RPASQDGRYE LEHLSTPEAH LDPSESHMQS
//
