ID A0A0P7WF30_9BACT Unreviewed; 1627 AA.
AC A0A0P7WF30;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=ATP-dependent DNA helicase RecQ {ECO:0000313|EMBL:KPP98447.1};
DE EC=3.6.4.12 {ECO:0000313|EMBL:KPP98447.1};
GN Name=recQ-2 {ECO:0000313|EMBL:KPP98447.1};
GN ORFNames=HLUCCA01_10605 {ECO:0000313|EMBL:KPP98447.1};
OS Bacteroidetes bacterium HLUCCA01.
OC Bacteria; Bacteroidota.
OX NCBI_TaxID=1666909 {ECO:0000313|EMBL:KPP98447.1, ECO:0000313|Proteomes:UP000050310};
RN [1] {ECO:0000313|EMBL:KPP98447.1, ECO:0000313|Proteomes:UP000050310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HLUCCA01 {ECO:0000313|EMBL:KPP98447.1};
RA Nelson W.C., Romine M.F., Lindemann S.R.;
RT "Identification and resolution of microdiversity through metagenomic
RT sequencing of parallel consortia.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP98447.1}.
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DR EMBL; LIHN01000009; KPP98447.1; -; Genomic_DNA.
DR STRING; 1666909.HLUCCA01_10605; -.
DR PATRIC; fig|1666909.3.peg.2653; -.
DR Proteomes; UP000050310; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 275..455
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 485..632
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1053..1463
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 1074..1081
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1627 AA; 185394 MW; 369A87B8E207DCDC CRC64;
MQNITFFDTE VDQRNQTVVD FGAIKGNDSY FHGASVHGFE NFLNGTEYLC GHNVVHHDVQ
YIRNLLQRVG IGPNNIIDTL FLSPLLFPKN PYHALVKDDK LQTEELNNPL NDSKKARYLF
QDEVDAYQKL DSDLAHIYFL LLHQTGEFRG FFRFMGSVHP KLELVDLIKR RFKNEVCDGI
NWSRLADSEP IALAYALSLI EAMKDGEGQA SITPPWVLKN FPDVERILSQ LRNTPCVQGC
SYCDSKLDIH LGLKKFFGFE SYRKYDDEPL QEQAVAAAVN HKSIIAVFPT GGGKSITFQV
PALISGESSR SLTVIISPLQ SLMKDQVDNL EEHGITQAVT INGLLDPIER AKSFQRVEDG
SATLLYISPE SLRSRTIEKL LLGRKIARFV IDEAHCFSAW GQDFRVDYLY IGDFIKSLQE
KKKLSEGIPV SCFTATAKRK VIEDIKDYFR DKLGLDLDVF SSSSSRKNLT YRVFQKDSND
DKYFALRDLI EEKNCPTIVY ASRTKTTESL AKRLSDDGFN ARAYHGKMEA KVKTLNQNEF
IAGNVGIMVA TSAFGMGVDK KDVGLVVHYE ISDSLENYVQ EAGRAGRDEN IVADCYVLYN
EEDLGKHFVM LNQTKLSIKE IQQVWRAIKD LTKLRSKVSN SALEIARKAG WDDAVAEIET
RVKTAIAALE GAGYLKRSQN VPRVFANSIL AKNAQDAIDK IEASNRFDQK QKVTATRIIK
KLIASRSRKG SPDDQAESRI DYISDHLGIT KEEVINTVGL LREEKILADD QDLAAYIRRT
EQKNRSLQIL KTFIKLESFL LDRVKVPDAV VNIKELNELA EQEGLLDIST QKIKRILNFW
VIRKQITQKI SRQSKNHLKL EPRIKLQEMR ERLEKRQELS AFILSHLFEQ IPESDLDATD
SQTEEVLVEF SVHALKKAYL ASESLFKVDV DIADIEDALF YLSRIEAIKI EGGFMVIHNS
LTIERLEENT KKQYTKDDYQ KLNDHYENKT QQIHIVGEYA KKMIEDYSGA LQFVEDYFQL
NYSAFLKRYF PGSKLDNLKL KMTPAKFQQL FGDLSPPQLS IIKDNEARYI VIAAGPGSGK
TKVLVHKLAS LLLMEDVKHE QLLMLTFSRA AATEFKKRLI HLIGNAANFV EIKTFHSYCF
DLLGKVGDLD KSNSILKVAT QKIIDNEVEQ SRITKTVLVI DEAQDMNEDE FGLIRALMSK
NEEMRVIAVG DDDQNIFAFR GSSSEYLQRL ISHHDAATYE LLDNYRSSVE LVQYFNSFVS
KINHRLKKNP IISRKSTGGK IRIIKHDEQT QRNSTLMIPP LVDDIISIGL SGTCGVLVKT
NYEALQITGQ LLKNGFPAKL IQSNDGFLLY NVDELRYFFN LLKNGDNDKY FITDEEWENA
KSRLTTVYAR STKLELLLNL TNDFEVTNPK RKFLSDLEVF IRESSLEDLH RHYGESILVS
TIHKAKGREF DNVFLLLDNF RIIDDASKRL LYVAMSRAKS LLNVHTNNDC LKNTFANNLH
FITHGNGYNP INEIVLQPTL KDVWLDFFIS KQQFLNRAIS GDKLTINGNL SLSLSGQEVV
RFSKKFTNDS ILPLLGDGYR MKEAKVNFVL WWQKEDSNRE IKVILPEIIL EKSGDRGDEH
RIGLNGV
//
