ID A0A0P7WR90_SCLFO Unreviewed; 946 AA.
AC A0A0P7WR90;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1-like {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=Z043_117321 {ECO:0000313|EMBL:KPP64342.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP64342.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP64342.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP64342.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP64342.1}.
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DR EMBL; JARO02007116; KPP64342.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7WR90; -.
DR STRING; 113540.ENSSFOP00015069814; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08837; ArfGap_ARAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 3.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR45899:SF3; ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45899; RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00788; RA; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00233; PH; 2.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 4.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 3.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 1..55
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 70..159
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 165..289
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT DOMAIN 374..481
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 539..729
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 763..849
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KPP64342.1"
SQ SEQUENCE 946 AA; 108211 MW; E39E864B7F2F20BD CRC64;
DVYSKRMIPI YSIMRVMSVG TQKFEVVTHN RTFLFRAQSD YERNTWVSLL QKTIEEQYGV
DRMTSDACGP IYIQGNLELR GIHSKLYMVV CEDKVILYKN TEEHKQGIGI TSIQMNLGSV
RETDKRAFDL TTPYRVFSFV AETEQMKQAW VEALQHAISS ALSSDSVVAK IWSQDSNRLC
ADCNATHPDW ASVNLCVVIC SRCAGEHRRL GSSVSKVRSL KMDRNVWTED LIKVFIMLGN
ERANLFWAAN VPPSEALCPS SSDTDRRAFI FAKYRQGKYR WYHKLFGQQE ALNKALCLNV
QTDDILETLS LLFCGADVNC HTEHPEFPTP VSLATRYNQT LQVEILKQNQ NTDSPGVDVE
DFVDANILND LRLSITHRGH LFKMASTTRP ITERKSREGE FSQSLCTLKK GIFSYGNSRS
SMPGRQLKVE EIVCLAINPP GTHGFEYTFE IYTEADRLYL FGENDPELVR EWIMVIVKSI
LPRNARDLGR LDFQRIGRLN YKARLSQQSP GVGWFALVGS ILHPRLPDHK EEEEDIDLCR
LQELCECKIC CAVRTRTLLI ESQLKLNFLG WAQDIQQASG SWGNTLAQQQ LTGTDIPIIN
FLVDARRIHL REEEHRVDDV AGTLKRFFRN VKEGVFTNQA APAWLSTIGG YKRRKSEDFP
LSVIAQQPPI SEQGHPGSPY CIQHFSNVNQ MNQHNLAIVF GPTLFQTDGT DSSAGKVIEE
LIQHYIPIFE VNEEQLQKQL HEVNLIVEIQ ESLMVETSPE PSSNIICTVY LEDGGQKEEL
HIKVDASMTA AALTSEVLEQ HKIQPQEFDY WCSFEVNEVE ETERPLHHRE LMLPVLQSAS
TVVVKKNDAM ETMLVYLASK LDISKYGMMK FRDERSLLSR GFQQRYVSIT GTTFRIYKEV
RSYRPEKECP IKSLTVFQGI KKKLRPPTSW GMTVVCDSEE QDRRQW
//
