ID A0A0P7WW55_SCLFO Unreviewed; 1114 AA.
AC A0A0P7WW55;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Sodium channel protein type 1 subunit alpha-like {ECO:0000313|EMBL:KPP68368.1};
DE Flags: Fragment;
GN ORFNames=Z043_112960 {ECO:0000313|EMBL:KPP68368.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP68368.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP68368.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP68368.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP68368.1}.
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DR EMBL; JARO02004526; KPP68368.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7WW55; -.
DR STRING; 113540.ENSSFOP00015075002; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 2.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR010526; Na_trans_assoc_dom.
DR InterPro; IPR024583; Na_trans_cytopl.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF278; SODIUM CHANNEL PROTEIN TYPE 2 SUBUNIT ALPHA; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 2.
DR Pfam; PF06512; Na_trans_assoc; 1.
DR Pfam; PF11933; Na_trans_cytopl; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 4: Predicted;
KW Ion channel {ECO:0000313|EMBL:KPP68368.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 112..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..773
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 785..807
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 874..894
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 956..979
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 157..411
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 527..705
FT /note="Voltage-gated Na+ ion channel cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF11933"
FT DOMAIN 755..986
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 993..1111
FT /note="Sodium ion transport-associated"
FT /evidence="ECO:0000259|Pfam:PF06512"
FT REGION 42..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..65
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..504
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1097..1114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1114
FT /evidence="ECO:0000313|EMBL:KPP68368.1"
SQ SEQUENCE 1114 AA; 126588 MW; 46AC4BB36F724F18 CRC64;
MKYTLKVQDE KMAQFPIPLG PDNFQLFTPK SLDAIEKRIA EQDDWKAKGE QFDDDDDEDE
RNSEPNSDLE AEKCLPFIYG DPAKGMVSTP LEDLDPYYRY QKTFIVLNRE KTIYRFNATS
ALYIFSPFNL LRRLSIKVLV RVPLLSTLVS LTVAITLFSK FIMLTILTNC VFMTMSNTPD
WSKIVEYVFT GIYTFECLIK ILARGFCIGK FTFLRDPWNW LDFTVIVLAY ATEFITLGNV
SVLRTFRVLR ALKTISVIPG LKTIVGALIQ SVKKLSDVMI LTVFFLSVFA LVGLQLFMGL
LRHKCIKIPI ANGSENQNNE NFFNWTIEYM NDRGRNPDYG YTSFDSFGWA FLSLFRLMTQ
DYWENLYKQT LRAAGKPYML FFVLVIFLAS FYLVNLILAV VAMAYEEQNQ ATIQEAKQKE
EKFQAMLEQL RMKQEEMQAA MAATESAQCD GNVGRMTHTS SEASKLSTKS AKERRNQRVK
RREDEEKGDH EKFSKSESED SMRPGFRFSV DGNLLSYEKR YSSPNQSLWS LRESSFSPRR
NRRSSLFSFH GQVRHAGSEN HFADDERSTI GDAVSRHGSL FVPRGQERRH SDVSRGSMSC
NRAVSSLGGT STDMCPAGLL LPVVTIHSPA VEDNVRKAKP GAPLLLLPAV SSCYTSSSAS
VSPAPCQDTF AETEIPQKKR SNSHQPSMEF LEDPVAKQRA LSVASILTTT VEDLEESRQK
WPMRWHRFAT TFLIWDCCPL WLKIKGFVRV LVMDPFMDLA ITICIVLNTL FMAAEYYQMS
SKFSYALSVG NSVFTSIFTT EMCLKIIALD PYYYFQEGWN VFDALIVSLS LMELGFANVE
RLSVLRSFRL LRVFKLAKSW PTLNMLIKII GNSVGALGNL TIVLAIIVFI FAVVGMQLFG
KNYRDCVCKI STDCKLPRWH MHDFFHSFLI VFRVLCGEWI ETMWDCMEVA GQSMCIIVFM
MVMVVGNLVV LNLFLALLLS SFSTDNLAAT EEDSEMNNLQ VAIGRINRGV RFVMTGLRQF
CRSQCFRRKR HKAPDETKTQ GEVNSSVGDQ FYNHIELSRE TDNMDKSICI TGDMASTSNP
TLLVSVPIAA GESDSENINI DDCSSESENE SCLE
//
