ID A0A0P7WY25_SCLFO Unreviewed; 666 AA.
AC A0A0P7WY25;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Fragile X mental retardation syndrome-related protein 2-like {ECO:0000313|EMBL:KPP69127.1};
DE Flags: Fragment;
GN ORFNames=Z043_112143 {ECO:0000313|EMBL:KPP69127.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP69127.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP69127.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP69127.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, Cytoplasmic ribonucleoprotein granule
CC {ECO:0000256|ARBA:ARBA00004331}.
CC -!- SIMILARITY: Belongs to the FMR1 family.
CC {ECO:0000256|ARBA:ARBA00006633}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP69127.1}.
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DR EMBL; JARO02004109; KPP69127.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7WY25; -.
DR STRING; 113540.ENSSFOP00015056864; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0036464; C:cytoplasmic ribonucleoprotein granule; IEA:UniProtKB-SubCell.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:InterPro.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR008395; Agenet-like_dom.
DR InterPro; IPR040148; FMR1.
DR InterPro; IPR022034; FMR1-like_C_core.
DR InterPro; IPR040472; FMRP_KH0.
DR InterPro; IPR032172; FXR1_C1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR041560; Tudor_FRM1.
DR PANTHER; PTHR10603; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN; 1.
DR PANTHER; PTHR10603:SF3; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN 2; 1.
DR Pfam; PF05641; Agenet; 1.
DR Pfam; PF12235; FXMRP1_C_core; 1.
DR Pfam; PF16096; FXR_C1; 1.
DR Pfam; PF00013; KH_1; 2.
DR Pfam; PF17904; KH_9; 1.
DR Pfam; PF18336; Tudor_FRX1; 1.
DR SMART; SM00322; KH; 2.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR PROSITE; PS51641; AGENET_LIKE; 2.
DR PROSITE; PS50084; KH_TYPE_1; 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 1..33
FT /note="Agenet-like"
FT /evidence="ECO:0000259|PROSITE:PS51641"
FT DOMAIN 46..98
FT /note="Agenet-like"
FT /evidence="ECO:0000259|PROSITE:PS51641"
FT REGION 388..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..474
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..550
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..625
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..647
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KPP69127.1"
SQ SEQUENCE 666 AA; 74058 MW; F21123BDBFA8CAD7 CRC64;
GFIKDVHDDS LTIVFENNWQ PERQLPFSDV RLPPPEDYHK EIGEGEEVEV YSRANEQEPC
GWWLARVRMM KGEFYVIEYA ACDATYNEIV TSERIRPVNP NSPSTRSTFH KIPIAVPEDL
RDICVNDAIH KDFRKAIGAN CIFYNTATHE LIVLSFLYSL QSTNESTVKR AALLSDMHFR
SIRTKLMLMS RNEEATKHLE TSKQLASAYQ EVVRVREDLM GLAIGSHGAN IQQARKVPGV
TAIELEEESC TFRIYGETPE AVKQARVYLE FKEDYFQVPR NLVGKVIGKN GKVIQEIVDK
SGVVRVRIEG DNDKKLPREE VGRQAASRED TAGDKEGMVP FVFVGTKENI SNAQALLEYH
VAYLQEVEQL RLERLQIDEQ LRQIGVGFRT PTSRSAGPGN AERDRGYLTD ESSNSIHGSR
TYGGRGRGRR ASNSQYSGYG TNSELSNASE SEDVVERDQK PRSTGDERGS RRGGRGRGST
AGVGRGRGTL GGRPASHTIS SVLRDPDSNP YSLLEGEGEQ GGDTDASESM GGAGDRRRRS
RRRRNDQEPS VMDAAAESDS QAGASENGLE EDGKPQRRNR SRRRRNRGSR PEGGSVSRDR
QPVTVADYIS RAESQSRQNL PQKEETQPAP EPKENGNSSR DERTPAKRSP SNGVATPSEP
VVNGVS
//
