ID A0A0P7X2E5_SCLFO Unreviewed; 2153 AA.
AC A0A0P7X2E5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Unconventional myosin-IXa-like {ECO:0000313|EMBL:KPP68310.1};
DE Flags: Fragment;
GN ORFNames=Z043_113018 {ECO:0000313|EMBL:KPP68310.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP68310.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP68310.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP68310.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP68310.1}.
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DR EMBL; JARO02004562; KPP68310.1; -; Genomic_DNA.
DR STRING; 113540.ENSSFOP00015034095; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000146; F:microfilament motor activity; IEA:InterPro.
DR GO; GO:0048468; P:cell development; IEA:UniProt.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd20883; C1_Myosin-IXa; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 2.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR046987; Myo9.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46184:SF3; UNCONVENTIONAL MYOSIN-IXA; 1.
DR PANTHER; PTHR46184; UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN; 1.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF00063; Myosin_head; 2.
DR Pfam; PF00620; RhoGAP; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00109; C1; 1.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 1..526
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1586..1635
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 1641..1829
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 278..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 408..430
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 824..916
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 929..953
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 977..1079
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1113..1132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1158..1180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1206..1425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1861..1908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2004..2153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 796..823
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 288..336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..857
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..911
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 985..1017
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1032
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1033..1048
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1052..1079
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1206..1239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1338..1374
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1403..1418
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2020..2037
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2038..2071
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KPP68310.1"
SQ SEQUENCE 2153 AA; 243970 MW; F74F4A7A8C173300 CRC64;
AGTVRDSMAK SLYSALFDWI VFRINHALLN NRDLEESAKI LSIGVLDIFG FEDYENNSFE
QFCINFANEH LQHYFNQHTF KLEQEEYRAE GISWLNIDYI DNSGCISLIC KKPTGLFHLL
DEECNFPQAT NQTLLDKFKR QHDGNSYIEF PAVMEPAFII RHYAGKVKYG VKDFREKNTD
HMRPDIVALL KSSRSAFIGS LISIDPVATF RWAVLRAYYR AAVAFREAGR RRSEKKSGRE
DAVPCAALKS VDTFSFLLHP VHQRSLEILQ RCKEEKHSIA RKSPRTPLSD LQGANTLNEK
SWGQESASST WSGRGTRSSR LNPSGQQLEE DGIMVNSTSS KLLERAQGIL MRNKNYKPKP
SLPKHLLDVK SVKYLSGLTL HDRITKSLLH LHKKKKPPSI SAQFQASLNK LMETLEQSEP
YFVKCIRSNA DKLPLRFSDS LVLRQLRYTG MLETVRIRQS GYSIKYSHED FAQHFRVLLA
EGTKPNQLSI QEFMRKADLS PGGFQVGRTM VFLREAERQR LQDLLHREVL RRIVALQRRF
RALRERKSFV SMRLAACVIQ RWWRSCRQKH MSAGGGSDHN RQQGAALQLQ AVWRGYRAHR
KFLQWREGAL VIQRRWRKWQ KRRNRAACTI QTAWRRHKER QSYCTLRSSI LLFQAACRGY
LARHRYGAAR AGFGSMHNCL SRVCMSMRTL AGLPWIRVNG RREMLSVYRF KDLKEQRLNE
KCLNGQSGPT PEKEQVHSIV GLDLCSWEDH SYKERAKKLE ALGTSLDSLR HGPEREAHLK
DAGHEWVRER SRTLEEPNLK TRAKRENRRM RELEQAKFSL EMLKVRSTGK ASPSEERQWS
LELIPKSTSS PKGVPDSKSL STDHHPQSKP GSSTVKEGSA PGEVPSDSPR SNGPPELLTS
SEFSTSPRTK MENLAPLPRI ENHLPIFYVP PKVPPAVASE STSKPCREKK STSRRPVVVV
ISMQRDALME DAMVVAPEVR DGSVQTDLSP VQPTVLAQTP PTAPSQDQPK SPSRASPIAT
PQTPPSAMPV DTPPTPATFS TSPLSNDQAV LERLERLQED SEEQRQQRQS EREMMEQIRG
QKLQLEKERV ALAQLERDRL ERKRSEALQR IQQSQQASGP AFPGPTLGAT SRAAGLEETG
PTTCQLPAIS HTKGREVSAL GPEPKEGMLL DTPPKKSHTH TISISMTDRS TNMFFIPRDN
KVSFSKSDKD LANQERSMAF KKDEASSSCR PPKGLKGREV VRPGRRKKAR MGRTRSDFMT
RGSSLEGEGD RESEEDEYDE VLLIHSQSPS PPLPEQDAEG GVEQACHSDS EMSSSFAGEQ
RKMHKAMSSG DLGKVDSLRK ASQADGRVRT RMRFWGKPKL GEKKGLREKS ASMGDSQEGD
GVDAGMHVGE RPLSPLQSLD LAPERSRESK ENKEPSPRAR RRRSVKISSV ALDAAPWQND
SLHMLTSVGD FRSMIDFLMK KISDLESEDS KKDTLVDVVF KKSLKEFRLN IFNSYSAALA
MDDGKSVIRY KDLHALFEHI LEKSMRQEQR DWGESPVRVW VNTFKVFLDE FMTECKPLET
TTGKVPKPER KKRRKKESDI VEEHNGHIFK STQYNIPTYC EYCSSIIWIM DRACVCKLCR
YACHRKCCLK TTTKCSKKFG VELSRLTSDD RPVPQVVEKL ISYIEMHGLY TEGIYRKSGS
TNKIKELKQG LDTDVDXMNL DDYNIHVIAR VFKQWLRDLP NPLLTFELYE EFLRAMGLQD
KREVIRGVYS VIDQLSRTHL STLERLIFHL VRIALQEETN RMSANALAIV FAPCILRCPD
SIDPLQSVQD ISKTTACVEL IIGEQMNKYK ARLKDITSLE YAENKARSRL TFIRRSMGKG
RLRRAASHTP SPPMSPRSAS RGEVPEESAG DEGVVGSDLS EQQQAALQQE ERVLAEQIEN
LQREKEELTF EILSLELRAS DDETLESEAS IGTADSFENL HVDSEGANIP GELSVWACPW
VTLLCGVPGG GRIRGKIRHP PHPLRPLCLP FLGRPPVATR PKRSDGKPRR PLRKQADSLD
SVDSSTSSAS SHHQPATYRF RFRSSSPPHS APPSHLIRAG VTSEAASAVA PEREAEERQQ
FPSYAPLSPE KGKQRLKSPP RWCDPPESSG RRGEPDFGSA QPLMLYSSNE FMV
//
