ID A0A0P7XF69_SCLFO Unreviewed; 666 AA.
AC A0A0P7XF69;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Protein numb-like {ECO:0000313|EMBL:KPP74171.1};
GN ORFNames=Z043_106684 {ECO:0000313|EMBL:KPP74171.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP74171.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP74171.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP74171.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in the process of neurogenesis.
CC {ECO:0000256|PIRNR:PIRNR017607}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP74171.1}.
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DR EMBL; JARO02001872; KPP74171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7XF69; -.
DR STRING; 113540.ENSSFOP00015009896; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR GO; GO:0050769; P:positive regulation of neurogenesis; IEA:UniProtKB-UniRule.
DR CDD; cd01268; PTB_Numb; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016698; Numb/numb-like.
DR InterPro; IPR010449; Numb_domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR47368; NUMB; 1.
DR PANTHER; PTHR47368:SF5; PROTEIN NUMB HOMOLOG; 1.
DR Pfam; PF06311; NumbF; 1.
DR Pfam; PF00640; PID; 1.
DR PIRSF; PIRSF017607; Numb/numb-like; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|PIRNR:PIRNR017607};
KW Neurogenesis {ECO:0000256|PIRNR:PIRNR017607};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805}.
FT DOMAIN 37..162
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 182..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 574..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..236
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..626
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 71782 MW; 5E30D61D03695FC7 CRC64;
MNKLRKSIRR KKDIYVPESS RPHQWQTDEE AVRTGKCSFA VKYLGHVEVE ESRGMHICED
AVKRLKMAGK KAVKAVLWVS ADGLRVVDDK TKDLILDQTI EKVSFCAPDR NFERAFSYIC
RDGTTRRWIC HCFMAIKDSG ERLSHAVGCA FAACLERKQK REKECGVTAT FDANRTTFTR
EGSFRVTTAT EQAEREEVMR QIQDTKRETE AKLSAPVPAS PATSLPGPPS PSSPPIPLIT
AVAAQDSNPH VIPRRHAPVE ALARQGSFRG FPNLSQKTSP FKRQLSLRMN ELPSTMQRKS
DFPIRNSVLE VEAEGDSISL LCTQITSAFS GQPEDPFSSA PMPKLVSPQS PAIPAVNGSA
AVFAPAANPS AAATPALPPP LPARDTNPWA KTSAGPVGYS PAQPDWTSPT RSRSGPVAPT
ASIPSTPTTL ASHKRTPSEA DRWLDEVSKS VRAQQPTPTT GTPAPVAHPF PTTIPSSIAS
GAPVAFMSAL PPAVPIVPPR QPAYHAQAPT SYPMANGLPY AQPSMPIVGI TPSQMVANVF
GTATQPQGLP PQGPPPQTQS QIFPATQVTI PQYDTLTPFS KPPQASTVAP ASLPTNGSTT
LNGDDSWAPP FLPPPSSPPP PLPAQPQEDA FEAQWAALEN RARQHTSPSP TNPFSNELHK
TFEIQL
//
