ID A0A0P7YNK2_9BACT Unreviewed; 1761 AA.
AC A0A0P7YNK2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=HLUCCX10_07230 {ECO:0000313|EMBL:KPQ16949.1};
OS Algoriphagus marincola HL-49.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Algoriphagus.
OX NCBI_TaxID=1305737 {ECO:0000313|EMBL:KPQ16949.1, ECO:0000313|Proteomes:UP000050421};
RN [1] {ECO:0000313|EMBL:KPQ16949.1, ECO:0000313|Proteomes:UP000050421}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HL-49 {ECO:0000313|EMBL:KPQ16949.1};
RA Nelson W.C., Romine M.F., Lindemann S.R.;
RT "Identification and resolution of microdiversity through metagenomic
RT sequencing of parallel consortia.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPQ16949.1}.
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DR EMBL; LJXT01000035; KPQ16949.1; -; Genomic_DNA.
DR STRING; 1305737.GCA_000526355_02492; -.
DR PATRIC; fig|1305737.6.peg.2087; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG3899; Bacteria.
DR eggNOG; COG4191; Bacteria.
DR OrthoDB; 9806704at2; -.
DR Proteomes; UP000050421; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:KPQ16949.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:KPQ16949.1};
KW Transferase {ECO:0000313|EMBL:KPQ16949.1}.
FT DOMAIN 6..263
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1507..1760
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 1457..1498
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1761 AA; 198677 MW; B0B0CE9CBB00E666 CRC64;
MNIGEYLLKN KLYEDIETSV YEAVHHKTGV KVIIKVHSDD FPSPHKIERV KDEFKIGENI
SGDGLAKYLE LIRIGNGFAI VQEFFAGTSL DNFLKNNNRL SIEEFLKIAP KITHAVGEMH
RQKIVHRDIS SDNILVAKDF SSIRLIDFGV SATFLKISSE KIAGGKIHYL SPEQTGRINR
LTDYRTDFYS LGVLFYRLLS GFFPFDGEDS YQIIHKHIAS PPPPFKNYLS NIPSVLEKII
FKLLSKSADD RYQSAKGLEK DLMKCAELYD ELGEIPEFKL AEYDFSTIFR MPRQLFGREK
ELKELMDYWE NSLNKKETQL LLVNGSPGIG KSALIQELKK PVLEQNGFFL HGKFELLNQP
IPYSGLIQAF ESLLSQLLSE HKKALSFWKD RLINALGQNG KLLTDVFPTL EKIIGPQAEI
ESLSPLESQN RFEYVFAEFI KVFTSQPYPI TLFLDDLQWI DLASLNLLSQ LLKNNQNQAF
FIVGAFRDTE VSINHPLRRM FEDLKKSGIT INQLELGLLP IDEINKILAY CLMRNNAEVV
EFAKQIHEKT SGNPFYVHRF IESLHEKGLI YSDPKKGRWE WNEAEIAIES ATENVVDFLM
KQMEKLPENV RHYLGTGAAI GNHFSGSELA GLNGLKESTL REDLSPALND SFLFFDGTNY
FFVHDRIQQA AYLFLKNKEQ VHLEIGEFFK EYLDRGKEDW VFRVTNQLNR AKSLITDPES
QIELAKYNYE AGIKARDAVA FDESLKLLNL ASALLQDKKP WVNQYDLIWN ISFAQIEVEF
IAGDQNKALN LANEVLGYAN SNFEKALIYN QLIIFSTMKI QFQEALDFGR KGLELIGLTT
PPDSELEAAI GQGFGTIISL MQGKKPLDLL KNRTLSEDEI SSIKIKLIVN MLSPAFLGGQ
SNLWTYLVLA STANSIENGN VAESCTAFSS YGILCGMAFN DYQQGFDFGD LSYQLSIDLK
SLRQRSNTCF VLGAFLNIYA RHAKEGFRYL KEGLSSGLQS GELQFAGYNI SGLGQVTTTS
GSSLSVLDER MYEGLQIAEK TKNQFVKSTI LVFYQLIHDL GGPSSLKEFE SEENIYALLE
KEQNYFGRFY FSLYKGFSSY LLGDAKGAYE HLANAKNYLS AVPGSVVLAD YYIYLPLIAL
ELIDLSNPEE DLQNSIEESI TILEKWNSSI PDNFQFRIDL IKAIKKDKEG HVLEALELYD
AAIDQATKQE MLPLKAIALE KAGIMMLNHG KSRIGEVYLK DAYLTYLEYG AINKVNQLQE
IYPTLFQKGQ KQKSLTISET TRTIQSLEMF DSQTLIKASS AISQEVTLKG VLSKMMEVVL
ENAGAERGYF IMHSDDSWKI EAEGIVNPRS YKLLQGVPYP SNAIKLPEEI INYVLNSHKS
LLLEDAQNHP EFGVTPYLDS AKVKSILCLP VIHQGMLLAI LYLENSLSIG AFTVSHKELL
QTLSTQIAIS ISNAQLYDNL ERKVHQRTAE LQLQKEDLEQ TLKDLRKTQR QLVNSEKMAS
MGELASGIAH EIQNPLNFVN NFTEVSDELI DEILAEYGKS LENRDEKIIQ ELLSDVKSNF
ERIRKHGLQA DAIVKNMLEH SKQGQGKNEP TDLNALANGS LRISYHSFLA KYKNIISKDV
EIEMDISTDM NLPKVNVIPQ EIGKVIFNLL NNGFYAVLDR STKENSAEFK PLVKITTSLA
KDPVSGPQAV ISVIDNGIGI PESIKEKIFQ PFFTTKPTGS GTGLGLSLAY EIIQAHGGQL
LLESKEREGS TFRIVLPVST N
//
