ID A0A0P7ZKZ6_9GAMM Unreviewed; 315 AA.
AC A0A0P7ZKZ6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:KPQ02771.1};
DE EC=1.1.1.95 {ECO:0000313|EMBL:KPQ02771.1};
GN Name=serA {ECO:0000313|EMBL:KPQ02771.1};
GN ORFNames=HLUCCO02_07865 {ECO:0000313|EMBL:KPQ02771.1};
OS Idiomarinaceae bacterium HL-53.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Idiomarinaceae.
OX NCBI_TaxID=1298881 {ECO:0000313|EMBL:KPQ02771.1, ECO:0000313|Proteomes:UP000053932};
RN [1] {ECO:0000313|EMBL:KPQ02771.1, ECO:0000313|Proteomes:UP000053932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HL-53 {ECO:0000313|EMBL:KPQ02771.1};
RA Nelson W.C., Romine M.F., Lindemann S.R.;
RT "Identification and resolution of microdiversity through metagenomic
RT sequencing of parallel consortia.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPQ02771.1}.
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DR EMBL; LIHO01000011; KPQ02771.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7ZKZ6; -.
DR STRING; 1298881.Ga0003345_0039; -.
DR PATRIC; fig|1298881.4.peg.1216; -.
DR Proteomes; UP000053932; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:UniProtKB-EC.
DR CDD; cd12172; PGDH_like_2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719,
KW ECO:0000313|EMBL:KPQ02771.1}.
FT DOMAIN 33..311
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 114..286
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 315 AA; 34519 MW; D3BC919CF0EF3148 CRC64;
MKRVLVTCPP MLGMFEQFIE PAKELGLELV PAQTTQVLSE EELIKLLPDY DGWIIGDDPA
TRQVFAAAKS GKLVAAVKWG IGVDNVDFEA CKDLGIPIIN TPNMFGTEVA DVAMAYLLGL
ARQTYFIDRE IRQNHAWPKP AGMSLTGKHI GVVGFGDIGY NVAKRLMGFD VTVTAYDPGV
EGNRDLQYVQ RKSWPEGLAK LDFLVFTCAL NKHNFHMLNA ETLSQLKAGT HIVNVARGPL
IDEKALIDAL ESGHITAAGL DVFEVEPLPK ESPLRKMPQC IFGSHNSSNT REGVIRASHK
ALSEIARFFN EVSAG
//
