ID   A0A0P7ZX78_9CYAN        Unreviewed;       476 AA.
AC   A0A0P7ZX78;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
GN   Name=norM-2 {ECO:0000313|EMBL:KPQ35006.1};
GN   ORFNames=HLUCCA11_12615 {ECO:0000313|EMBL:KPQ35006.1};
OS   Phormidesmis priestleyi Ana.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales; Leptolyngbyaceae;
OC   Phormidesmis.
OX   NCBI_TaxID=1666911 {ECO:0000313|EMBL:KPQ35006.1, ECO:0000313|Proteomes:UP000050465};
RN   [1] {ECO:0000313|EMBL:KPQ35006.1, ECO:0000313|Proteomes:UP000050465}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ana {ECO:0000313|EMBL:KPQ35006.1};
RA   Nelson W.C., Romine M.F., Lindemann S.R.;
RT   "Identification and resolution of microdiversity through metagenomic
RT   sequencing of parallel consortia.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPQ35006.1}.
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DR   EMBL; LJZR01000015; KPQ35006.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0P7ZX78; -.
DR   STRING; 1666911.HLUCCA11_12615; -.
DR   PATRIC; fig|1666911.3.peg.4675; -.
DR   Proteomes; UP000050465; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   CDD; cd13131; MATE_NorM_like; 1.
DR   InterPro; IPR002528; MATE_fam.
DR   InterPro; IPR048279; MdtK-like.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR   PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR   Pfam; PF01554; MatE; 2.
DR   PIRSF; PIRSF006603; DinF; 1.
PE   4: Predicted;
KW   Antiport {ECO:0000256|ARBA:ARBA00022449};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        68..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        107..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        144..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        173..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        248..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        290..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        367..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        438..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   476 AA;  51520 MW;  C36479D43D8D3C17 CRC64;
     MNWSVLQSRA KSRLTASGVV PEGRAFLGLA VPLATAQVAQ FAVGFVDTLM MGHLNTASLA
     AGGLASTTFQ MLLTIVSGFV MSVGVLAAEA YGSEKKKRLT GLARQGLWLT LLLAVPLTLL
     LLQMSPILEF LGQSEQVRQL SQHYFSWISI GVLPALGFAM LRGYVSAFSL ANVVTVIVML
     GTGFNIGCNY VLGFGKLGFP RMELAGFGLG SSLSLWLMFG LFAAYILRHP ELNQYRFWRG
     RQHPDMAILR RLVAIGLPMA VTFTLELGLF LAVSYMAGSL GTEVLAAHQI AFQTMALIFM
     VPIGMSQAVT TRVGLWHGRK SRRGVRRAGL VAIAAAVLFL AGCAIALSHY RAFMVGLFID
     MRDPQNAPVI AIAMSLLLIA AIGQTLDGIQ RVAMSALYGL QDTRVPMIMS AIAFWGIGLP
     IGYLLGFRLG WGAAGLWVGQ YMGVAIAGII FLWRFCKLTS HKRRSQTLIT NADHKR
//