ID   A0A0P8CLM2_9EURY        Unreviewed;       428 AA.
AC   A0A0P8CLM2;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Trypsin {ECO:0000313|EMBL:KPQ44142.1};
GN   ORFNames=MPEBLZ_01281 {ECO:0000313|EMBL:KPQ44142.1};
OS   Candidatus Methanoperedens sp. BLZ1.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Candidatus Methanoperedenaceae; Methanoperedens.
OX   NCBI_TaxID=1719120 {ECO:0000313|EMBL:KPQ44142.1, ECO:0000313|Proteomes:UP000050360};
RN   [1] {ECO:0000313|EMBL:KPQ44142.1, ECO:0000313|Proteomes:UP000050360}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Arshad A., Speth D.R., De Graaf R.M., Op Den Camp H.J., Jetten M.S.,
RA   Welte C.U.;
RT   "A metagenomics-based metabolic model of nitrate-dependent anaerobic
RT   oxidation of methane by Methanoperedens-like archaea.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the peptidase S1B family.
CC       {ECO:0000256|ARBA:ARBA00008764}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPQ44142.1}.
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DR   EMBL; LKCM01000106; KPQ44142.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0P8CLM2; -.
DR   PATRIC; fig|1719120.3.peg.1375; -.
DR   Proteomes; UP000050360; Unassembled WGS sequence.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 2.60.120.380; -; 1.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR007280; Peptidase_C_arc/bac.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR008256; Peptidase_S1B.
DR   InterPro; IPR000126; V8_ser_AS.
DR   PANTHER; PTHR15462; SERINE PROTEASE; 1.
DR   PANTHER; PTHR15462:SF8; SERINE PROTEASE; 1.
DR   Pfam; PF04151; PPC; 1.
DR   Pfam; PF13365; Trypsin_2; 1.
DR   PRINTS; PR00839; V8PROTEASE.
DR   SUPFAM; SSF89260; Collagen-binding domain; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR   PROSITE; PS00673; V8_SER; 1.
PE   3: Inferred from homology;
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          348..408
FT                   /note="Peptidase C-terminal archaeal/bacterial"
FT                   /evidence="ECO:0000259|Pfam:PF04151"
SQ   SEQUENCE   428 AA;  46840 MW;  6556EA23A72AC0AB CRC64;
     MSDGKNDLIK KLNSFEADQL LGELKSRPKK VRSSGPFQDV DSATIAKVLK DKQKAIYGVD
     DRKDLFLVDD QGILNDADCV VSLFQNREVV DNGDGTSTLA VKNFGTEYNL CNNERFREQP
     TGAFCSGFLV APDLVATAGH CVNPSNVTNI LFVFGFRMVD ETTPHTNIDN NEIYRGLKVI
     DRKEISDGSD WAVVKLERAV ANHRITDFRR TGIIQNNQAV HVIGHPCGLP TKFAGGARVR
     DNTSGEFFVA NLDTYGGNSG SPVFNSDTHQ VEGILVRGAT DFASSNGCDV SLVCPSSGCR
     GEDCTKTTEF SYLFGQENGP EVILLDTTIS SMLPDKDSIK EYVIKGIESG KKLIINLEGP
     EGQDFDLYVK FGSLAKVDDW DSRGYTSDPN EEVTIDPTEQ GDYYITVHAF AGKGNFNLKA
     NTMSSEND
//