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Database: UniProt
Entry: A0A0P8D2C1_9ALTE
LinkDB: A0A0P8D2C1_9ALTE
Original site: A0A0P8D2C1_9ALTE 
ID   A0A0P8D2C1_9ALTE        Unreviewed;       350 AA.
AC   A0A0P8D2C1;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   08-MAY-2019, entry version 21.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=aroF-2 {ECO:0000313|EMBL:KPQ29860.1};
GN   ORFNames=HLUCCX14_04325 {ECO:0000313|EMBL:KPQ29860.1};
OS   Marinobacter excellens HL-55.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Marinobacter.
OX   NCBI_TaxID=1305731 {ECO:0000313|EMBL:KPQ29860.1, ECO:0000313|Proteomes:UP000050416};
RN   [1] {ECO:0000313|EMBL:KPQ29860.1, ECO:0000313|Proteomes:UP000050416}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HL-55 {ECO:0000313|EMBL:KPQ29860.1};
RA   Nelson W.C., Romine M.F., Lindemann S.R.;
RT   "Identification and resolution of microdiversity through metagenomic
RT   sequencing of parallel consortia.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KPQ29860.1}.
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DR   EMBL; LJZQ01000004; KPQ29860.1; -; Genomic_DNA.
DR   RefSeq; WP_044389192.1; NZ_JYNR01000001.1.
DR   EnsemblBacteria; KPQ29860; KPQ29860; HLUCCX14_04325.
DR   PATRIC; fig|1305731.5.peg.2961; -.
DR   OrthoDB; 853329at2; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000050416; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000050416};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:KPQ29860.1}.
FT   DOMAIN       54    346       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   350 AA;  37985 MW;  6002BE5C708E5638 CRC64;
     MNMPLKSETL DTHTVSACQH RQEATLPTAA ELRQQFPAGE PLTRAIAGYR DQIRSVLHGQ
     DPRTLIVMGP CSLHDEKAAL EYGARLKTLA DDVSDQFLIV MRAYLEKPRT TVGWKGLLYD
     PERTGQGDLK QGLERSRKLL LELSELGLPL ATEALSPFMM DYLGDLVSWT AIGARTTESQ
     IHREMVSGLP MPTGFKNGTD GGIAVATHAM QSASYPHHHL GISHAGAPVM VTTAGNPDTH
     LVLRGGRGVT NYDAGSIAKA VAELQKAGVS TAVMVDCSHD NACKQAERQL GIAREVMAQK
     RAGNTHIKGL MLESFLTFGR QDDGDDLIYG CSITDPCLAW EQTEALIRSL
//
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