ID A0A0P8XRF5_DROAN Unreviewed; 8701 AA.
AC A0A0P8XRF5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Uncharacterized protein, isoform U {ECO:0000313|EMBL:KPU77143.1};
GN Name=Dana\GF11157 {ECO:0000313|EMBL:KPU77143.1};
GN Synonyms=dana_GLEANR_11226 {ECO:0000313|EMBL:KPU77143.1};
GN ORFNames=GF11157 {ECO:0000313|EMBL:KPU77143.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:KPU77143.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:KPU77143.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR EMBL; CH902619; KPU77143.1; -; Genomic_DNA.
DR RefSeq; XP_014762564.1; XM_014907078.1.
DR EnsemblMetazoa; FBtr0385904; FBpp0345819; FBgn0088197.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd21189; CH_PLEC-like_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR CDD; cd00176; SPEC; 18.
DR Gene3D; 1.20.58.60; -; 30.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 1.
DR Gene3D; 3.90.1290.10; Plakin repeat; 11.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF02187; GAS2; 1.
DR Pfam; PF00681; Plectin; 1.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF00435; Spectrin; 17.
DR Pfam; PF21020; Spectrin_4; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00243; GAS2; 1.
DR SMART; SM00250; PLEC; 31.
DR SMART; SM00150; SPEC; 37.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF143575; GAS2 domain-like; 1.
DR SUPFAM; SSF75399; Plakin repeat; 14.
DR SUPFAM; SSF46966; Spectrin repeat; 34.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS51460; GAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 37..160
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 172..277
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 823..881
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 8290..8325
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8326..8361
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8366..8438
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 2756..2781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2807..2832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2872..2906
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3016..3145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3184..3208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3232..3328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5493..5554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8137..8230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8465..8498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8510..8701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 388..472
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 963..990
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5169..5200
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5315..5342
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5575..5638
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5874..5901
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6198..6334
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6418..6445
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6738..6765
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 7469..7534
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2885..2906
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3020..3053
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3184..3200
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3232..3251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3253..3284
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3286..3309
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5526..5554
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8167..8181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8182..8203
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8204..8218
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8465..8495
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8513..8538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8546..8688
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 8701 AA; 979248 MW; A2EA00191EE1E471 CRC64;
MMDRESLSEW AKDKPLSILQ LDPADRAVLR IADERDAIQK KTFTKWVNKH LKKTYTMLHV
CVTTNGIPCC SQSANRRVVD LFEDLRDGHN LLSLLEVLSG EHLPREKGKM RFHMLQNAQM
ALDFLRYKKI KLVNIRAEDI VDGNPKLTLG LIWTIILHFQ ISDIVVGKED NVSAREALLR
WARRSTARYP GVRVNDFTSS WRDGLAFSAL VHRNRPDLLD WRKARNDRPR DRLETAFHIV
EKEYGVTRLL DPEDVDTNEP DEKSLITYIS SLYDVFPEPP SIHPLFDMES QRRVHEYRDL
AQQFIYWCRE KTAYLQERSF PPTLIEMKRL LSDLQRFRSE EVSARKREKS KLIQIYKELE
RYFETVGEVD VEAELRPDAI EKAWYRMNTA LQDREVILQQ EIERLERLQR LADKVQREIK
HVDQKLTDLE TRIVEEGRRI ERLHPVDAKS IVEALETEIR HLEEPIQDMN QDCHVLNEGR
YPHVSELHKK VNKLHQRWAQ LRTNFHTNLV QKLSGLKYPV HETTVTRQTR MVVESRQIDT
NPHFRDLQEH IEWCQNKLKQ LLAADYGSDL PSVKEELDRQ QHEHKIIDQF HSKILNDERQ
QTKFSGDELA LYQQRLNQLQ KVYAELLSTS TKRLSDLDSL QHFLGQASAE LQWLNEKEQV
EISRDWADKQ LDLPSVHRYY ENLMSELEKR EMHFATILDR GEALLNQQHP ASKCIEAHLT
ALQQQWAWLL QLTLCLEVHL KHATEYHQFF GEIKDAEQWL AKRDEILNSK FSQSDFGLDQ
GETLLRGMQD LREELNAFGE TVATLQRRAQ TVVPLNKRRQ PVNRQGPVQA ICAYKQQGQL
QIEKGETVTL LDNSGRVKWR VRTSKGQEGS IPGACLLLPP PDQEAIDAAE RLKRLFDRSV
ALWQKKHLRL RQNMIFATIR VVKGWDFDQF LAMGPEQRTA IRRALNDDAD KLLSEGDPND
PQLRRLRREM DEVNRLFDEF EKRARAEEES KQASRIFTEE CIAIKSKLED MARELDQIIL
APLPRDLDSL EHVLEIHADY ERRLHLLEPE LKHLQETFRT IALKTPVLKK SLDNLMELWK
ELNTQSGLHK DRLKLLEASL AGLEDNEHVI SELENELAKH QDLPSTAEGL QQVFKQLTHM
QDVITQQQPQ MDKMNDAADQ LGRMGVPTKV LGDLKRLHSN VERLNTRWSA VCNQLAERMR
SCETAIGLMK NLQSSVQVEE SWVDGTTERL SAMPTATSAY ELDKLLGAAI ERKPKIENVN
VAGGRLIREA KIYDSKCLRF VDWLLEARPS FSPPRRDLRP ADSDPGATQY YSQRLDNLNT
KYDRLLEQLS QRLKTAIEVN GSDGLQYAES LQKPLKTFRV DFSAGSVPTG DGYAARPEDL
YTTTYSTTQF SSTKTTKSST KSVYSSDGLD AASQEVITSN LPPSQIQFNE IRTLKRSQQL
GGNSVLDIAG IRDPRTGRVL TIGEAIQLRI LDVRTGEMLV GDRRISLEQA AEQGLIDAQL
ARQLLQPGAG RDASGRELSL LEVIQREINE AESGYETAEK RIKVNSTVTV ESTGSPENPR
NIADAITAGS VDTKTGLYRV KSGQTISLAE AYERGYLIRH ESVTIKSNAL CLSDAIAHGL
VDGAGWIADR NSGDKFRLDS AIANQLIDAG VREVVDAKRD TKITLQEALQ SGVLNAKTGR
YVNEVTKEKL TFAEARNRQL IVKPYTLKDI CDLNLLDKQA QITSPMRREK LSIMQAIEAG
VLDGNNLKCI TKRKGELVTL QEAIADGIVL PAECKYRDFM TGELISIPEA VERGLISSVA
QRSIFDIDGF KDLRSSDYVS FNVALSRDLL RRKSTGFALE TGRDSLVPLE VAVGEGLVRQ
EVYEMFNRGI GVQNASGQEL SVFDLVYHNL IDPKTGYLLD PKTGETVPLD TAIERKFITA
EGALLLSSLL NITLTTETVT RTINRYVTIR AGSQEPGDQV LLTFTEAVRQ GFIDEERQLF
KDPKTGNIYS VQQALNYGLL VPDSNQTVPE PTNRKKTKST ITIVTKQIIP EAEPIKLNTQ
HTKYVEKSVE IPISQELIKP QRVVSDFINM EKSSYIEQNV TERQIMELPP GGWRLKDAIE
QRIFNPDTGV FHVQGTDRLV NFEECINKQI INNLSVSIID PSTGDKISVQ SAFERDILDS
YGNYTNSRKQ VLGMRSAIDE GKIILETVPA TRGSSQKTIL RITRVNNMPD VLEVSTPLKD
APPKFVEVST CQRELASPEP LQIAPGAIYD PSTALVIFTQ SGETENIFDA ARQGLIDEQL
IKIVDPRTKQ PISVTEAIAR SIYDPKTETI LDAEGQPVDL ITATKLGLLS VVGAPLVAAE
GALRTVRFVT DPRTGEQIPV EVAYERGIVS RDQLQRGRSF DSEPSTTTVE EKVVVLQRMR
KIILKPKDAL RKGIIDEETC KILEDTNNFT NPQGEVVNIT EALNTGMIDG RRGKIIDPQS
NRVLNLRQAV EQKILDPEQT NHILMPLAKS LSVPRLAAQG LVDPKTQTIV HPESGYPLSI
HEAIVCEVLD PHSTLRKPEK CTLEAAIKKG IVDADESIFK YKNKNLNISE AIEARLFDPS
YDQQKSKVDI PPVGMIFPVA VEKSLVEPSK RVVLHPSTKN ALPIKQAIDE NFIMSIPYAP
KKDAIEVVAA MERDLIDVAA QTITVPTTGE RLPLRQAMEN GVLVVKQLSD FVVTQKPIPK
TEIMETVRAV HTVTTKTIEL MQGYVLISNN EVQNVNTGEV VSLEEAKELG ILREESTTRE
TKAAAGESPE AVQNLPTSSD QTVVVEERTQ TVVVSSDTHK QEMQVISTTQ STKENPAIPT
VSEAETKVGK EPSKTLQNVK DAAKMGALGV IAAPVLAGGA LVSGVKSLIK SVKSPAEDAK
TTTQKPEKPQ SSFIEQERRN VPEPQQVPSE VDNLLNETEN FISSTTANFI INEQQQEKPQ
EVSRQEVEST NTLTTTTVTT ITTSKTTTET GDAEPVVVED VKTTTTVETT PVEPEIAKKP
EDKPVDVQVT ETITTVTREE TISEPEKPTT KEPTPEKIVE KKPVEKPAKK ETTPAPVTKE
TTPAPVTKEP TPEPIQKEKT PEPAPREAAQ VPTKPEPQPR TAVKEEVPAF EPPFTAPLAP
FEEPKAETKI TEVTTEVQEP VSSTETITTI TTTVTTIDQQ PKEVTEVDKS EPAKITEVEV
EKPAVQEPIK DDKPSEILDE VSEEPTSSIV VEERVITVEE PTITESTVTT TITTTTTTTS
SEEQQPQETV VTEIVKEEPK KDTPQPEKTV VTEELVKEEP AKDASQPITE PTQTTETVTT
TTTIIQEEKP QQPGDLEQIV QPPTSTNKHQ SVVDFIQAEK NTQPSEGSKV LQNVKDAAKL
GALAIVGAPV LAGKALVDAL TSDKATKTGQ PTTHVVTEIV EELPADISRT TSTIVTKVTT
TTTTTTTTGE GSPEDEARDV VELPISSAEP TIKREVPKTL PIGDAISQKL ISPDECQVIV
DGEQQSQTVS TLLKEEQLSP LDEVQIIDDK LIILQQISYL VDVDTELTPE KLSELNIYDP
ENQYFIDPTT GQKISFQTLV FDMNIFNPET ILVKNFSTGK YETLTAALER PLLDRHTGHM
VDPKTGKKIP FFECIERQWI IRADPEEQKP TGMENVTIDP QTGQVILDDG RVCSIVEAIN
SGKLDIQSIS VRDPVSGEVI PLRMAIELGV VDMQAGTVID IQTLKEIPME LAFQLGFLVP
GARKPISLEA AVRKGLYDPE TGKLFDSESQ NQVDVQKSIE IGLVDPKISL IVDTVTKKEV
KLDCAIEDEL VVPSTGQIKD NKNNTLVPFD VGVQQRLVKT DSVTWSLPEV LQREYYTPST
GKVLNPVTGE EILLQQAIEM GFVELDTTLV KDADHDKIVP GKEAAKVGLL DTVRGTLSSP
NISLDEAFVK GYLISTKKPL SLVDCLLRGL YDPSTAKFTI DDKQLDLKSA IAQKLINPEE
LVLLDPKTES IISLTEAIAK GYLDPIGGYV INPYTSTKLS LHEALENRIL IPPKRKRSLP
DAVYRGLYDP KTGQFSNTVT REKLTTERAI RRGILDPDST VVNVGSGQII PFGVATETGI
VDSRQGTVKD QDDKSIDFKE AFDRGVLVEA KKPLRLIEAV VKNVYDEVDG HFVDPKSGEK
LNFAEALNTN LLDEHSVQIR DFKTGLYKQL NLTHAKDSGV IDAQNSKLLY NNQTMTLKHA
FDIGILMDVN APISIQRAIH QGLFDDKTGK LSDPRSGRQI TLLEGMRSFV INPHLSCYFD
EQTETMYSLS ETCRNGIINR REGVFREPGS SSFVPLGEAL SLGLIVDIEN AGFGLYELLS
MGFYDTPTRK VLHPVTNRKL NLNEACVEDV VSLSSSLVKH HETGKYLRLA NAIKEQLIDD
NRGCYNLGNE QLDLQAARAR GFIVSNRRLL SLELVLRQQL YRPETGKFCD PTTGEYLDLI
EAIHSGFIDP ATTVFKNQLT GKELPLGEAI ENGDIDVSKG RVFDPKSKSA YNYDVALARG
ILVTVARPLT DRSEVVRRQD SVELLGQTPV SVVISKPREM SLEEAIRYNI IDPKTALVRD
FDSFKFLPYS VAVERGLVDT TKRTLVDPKA LYFAFDPTLI VYVREPITFD QAAESKCLDL
QTGILTYVPV SSATGNESAP AGDDSANDSL TVIETPKVYT LKEAASAGVV DPDSALVKDL
AKAKLVRLPE AFRKGLMDAN KANVLNTQTS KLCTLQEAYE SGLICTPKRS FGLLEAITFN
LYNPTNGCLV DPFQMHPDII RRRKFTLAEA IGSGLVDPSS TVVRDPSSGV IVPLTAAIGS
GLIDAAEGRL TDASDPKNNI DLVKAAEKGL LLPAEQRQAV FEKFNMCEEN VNDLLKWVTT
VEQKISSVGG PREKIDELRN QINALKQIKD EIESQQRPVA TCLEQIRQIV LTGGDVLSAP
EVTTLENSGR ELRSRVDRVN DRTVRLLRRL EAGRDELTKL RSELDVFSDW LQVARRTLED
KERSLSDLTR LPSQADSVRE FVSDVIGHQA DLRFITMAAQ KFVDESKEFL AILNDFRTSL
PERLPHVEPL SSAESPIRQE VSLVSAQYKD LLNRVNALQD RVSGLGGRQR EYQDALDKAN
EWLRSIAPRV SRIIAEPIAG DPKGVQDQMN EAKALHNELL SSGRLVDNAQ QALDNLLRSL
GGQLSPMEIN QLELPIADLK NNYQQLLDNL GEHCKNLDKT LVQSQGVQDA LDSLVGWVNQ
AEDKFKLNLR PASLIKERLQ EQIREHKVLL ADLQSHQASI DSVQISAKHL LASASNARIA
KKVESNLNDV TGKFEKLYEK ANKRGEFLDD VYNRLGRYLD DISNVEQRMA SLQEALDSRE
TSLLSTEELA RRMNDLSREK DHLAPQFEDC VRNGKDLIGL RDVTDTGVLR DRIKALESQW
RNINISIDER AKLSKQKAEQ QLAYEGLKDQ VLSWLASTEA RVNGLPPVAI DLDRIKQQHD
ELKPICKDYR DYAPTIDKIN DIGAQYDALI RPESPARKRS TYSPIKRASP LRRMSGDARS
PSPTKGGILS PLSTGSSGFG SRRSSQDGFQ LSELSPVQQQ LSEINNRYGL IGVRLNDRQH
ELDNLSEELR KQYDNLKGLA QFLERIQRQV PKESVSNKDE AERCIKQARK ILEDMYEKQS
LLDTTKAQIK DILRRKSDVP GAEQLRLENE NIQEKWKNLN DICKNRIAFS EKLRDFLDTH
GNLKSWLDSK ERMLTVLGPI SSDPRMVQSQ VQQVQVLREE FRTQQPQLKH FQELGHDVVD
HLAGTPDAQA VEVKLKDILG KWEDLVGKLD DRANSLGGAA DSSKEFDAAV NRLREALQNI
SDNLDALPTD GDHQENLRKI ENLERQLEGQ RPLLADVEQS AATLCNILGD PASRADVNSR
VAALEKQYLA LQKKLDTKKA ETEASLRDGR HFAENCSKTL GWLGGELSNL TDRLLVSAHK
PTLQHQIDTH EPIYREVMAR EHEVIMLINK GKDLSDRQQD RGVKRDLDRI QQQWEKLRRE
AVDRHTRLQT CMEHCKKYSQ TSEQFLAWLR TAEDKLSDLT PGVLSKAKLE TRLRDLQTFR
SEVWKHSGEF ENTKGLGETF LTSCDIDKEP IKAELQDIRD RWERLNNDLI ARAHEIENCS
RRLGDFNDEL RNLDHSLGRC EDRLAAHDAL GGAAKDPKLL ERVKAIREEL TNLSKPLQSL
KALAKDISAE ARAAGGDADH LTSEVDGLAD RMSELQGRLD DRCGELQSAA TAVSQFNEQM
KSLGIDLNDL ETEIEKLSPP AREIKIVQQQ LDDVGKIQHK LDRLVGRLED AERAADVLVD
AGFAADTTQT REQISTLRKT LGRLDNRVRD HEDNLQATLK ALREFYDNQS TTLDDIQDVS
EEFKRMKPVG SELDQIRRQQ EDFRNFRERK VEPLAVNVDK VNVAGRDLVR SAGSGVSTTA
IEKDLEKLND RWNDLKERMN ERDRRLDVAL LQSGKFQEAL AGLSKWLSDT EEMVANQKPP
SSDYKVVKAQ LQEQKFLKKM LLDRQNSMGS LANLGKEVAN HCEPAERASI EKQLNDLMKR
FDALTDGAEQ RELDLEEAME VAKRFHDKIS PLELWLDNTE RAVKSMELIP TDEEKIQQRI
REHDRLHDEI LGKKPDFTDL ADVAAQLMHL VSDEEAVNLG EKVRGVTERY TGLVDASDNI
GALLSESRQG LRHLVLSYQD LVAWMESMEA ELKRFKSVPV YAEKLLEQMD HLLELNENIA
GHASNVESTV ESGAELMKHI SNDEAIQLKD KLDSLQRRYG DLTNRGGDLL KSAQNALPLV
QQFHEAHNRL VEWMQSAEAA LAPSEPRQSD VLRLEGELAD MRPILDTINL IGPQLCQLSP
GEGAATIESI VTRDNRRFDS IVEQIQRKAE RLHLSNQRAK EVTGDIDELL EWFREMDTTL
READPPAMEP KLVRAQLQEH RSINDDISSQ KGRVRDVTAA SKKVLRESPQ SENTATLREK
LDDLKEIVDT VAQLCSERLG ILEQALPLSE HFADSHQGLT AWLDDMEQQI SRLSMPALRP
DQITLQQDKN ERLLQSIAEH KPLLDKLNKT GEALGALVAD EDSAKINEIL DTDNARYAAL
RLELRERQQA LESALQESSQ FSDKLEGMLR ALANTVDQVN QLDPLSALPQ KIREQIEDND
ALMDDLDKRQ DAFSAVQRAA NDVIAKAGNK SDPAVRDIKA KLEKLNNLWN DVQNATKKRG
SSLDDILSVA EPFWKQLNSV MKTLKDLEET LSCQEPPAAQ PQDIKKQQVA LQEIRHEIDQ
TKPEVEQVRR HGSNLMNMCG EPDKPEVKKH IEDLDNAWDN ITALYAKREE NLIDAMEKAM
EFHETLQNLL KFLTKAEDKF AHLGAVGSDI DAVKRQIEQL KSFKDEVDPH MVEVEALNRQ
AVELTERTSP EQAASIREPL SVVNRRWEAL LRGMVERQKQ LEHALLHLGQ FQHALNELLV
WINKTDGTLD QLKPIPGDPQ LLEVELAKLK VLANDIQAHQ NSVDTLNDAG RQLIETEKGS
LEASTTQEKL RKLNNEWKQL LQKASDRQHE LEEALREAHG YIAEVQDILG WLGDVDAVIG
ASKPVGGLPE TATEQLERFM EVYNELEENR PKVETIQAQG QEYIKRQNQM KVSSSNLQHT
LRTLKQRWDA VVSRASDKKI KLEIALKEAT EFHDTLQAFV EWLTQAEKLL SNAEPVSRVL
ETIQAQMEEH KVLQKDVSTH REAMLLLDKK GTHLKYFSQK QDVILIKNLL VSVQHRWERV
VSKAAERTRA LDHGYKEARE FNDAWSGMMQ YLQETEQVLD QIIEEATASK EPQKIKKYIG
KLKETHRQLG AKQSVYDGTM RTGKNLMERA PKGDRPVLDK MLLELKEQWT RVWSKSIERQ
RKLEEALLLS GQFSDALGEL LDWLKKAKSR LNENGPVHGD LETVQGLCEH HKHIEQDLQK
RAAQMQGVLK TGRDLERSGN NPEVGRQLDE MQSIWEEVKN AVAKRGDRLQ VALVDAEKLN
ARVQALFDWL DHAEHKLRYA KNAPDDEKVS REMMDIHMEF MKDLRVRERE KTETFEYAED
IIGKAYPDAI PIIKNWLSII QQRWEEVRQW AINRESKLEQ HLQSLKDLDD TIEELLAWLS
GLEGTLLNLK HERLPDEIPP VEKLIEDHKE FMENTARRQN EVDRACKPRQ LPPGARKPSR
SGKTPVRGSS HDLRETSPDG TLRRQSFKGS RDQGLNARKG SRVTPTRDTP DRDRLPHYGP
RFSPSTAGPE LEFRSPRAKL LWTKWRDVWM LSWERQRLLY DHLLYLKDVE RARNFSWDDW
RKRFLKYMNH KKSRLTDLFR KMDKDNNGMI PRDVFIDGIL NTKFDTSGLE MKAVADLFDR
NGEGLIDWQE FIAALRPDWQ ERKPATDSDK IHDEVKRLVM LCTCRQKFRV FQVGEGKYRF
GDSQKLRLVR ILRSTVMVRV GGGWVALDEF LQKNDPCRAK GRTNIELREQ FILADGVSQS
MAAFTPRRST PNAAATASSS PNAQNGGSSN LPPYMSGQGP IIKVRERSVR SIPMSRPSRS
SLSASTPDSL SDNEGSHGGP SGRYTPRKVT YTSTRTGLTP GGSRAGSKPN SRPLSRQGSK
PPSRQGSTLS LDSTDDHTPS RIPQRKPSTA STTSGTTPRP ARLSVTSTTP GSRLNGTSTI
TRKTASGSAS PAPTRRNISG SSTPSGMQTP RKSSAEPTFS STMRRTSRGT TPTEKREPFR
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