ID A0A0P8XYQ0_DROAN Unreviewed; 1624 AA.
AC A0A0P8XYQ0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Uncharacterized protein, isoform C {ECO:0000313|EMBL:KPU79745.1};
GN Name=Dana\GF17001 {ECO:0000313|EMBL:KPU79745.1};
GN Synonyms=dana_GLEANR_18269 {ECO:0000313|EMBL:KPU79745.1};
GN ORFNames=GF17001 {ECO:0000313|EMBL:KPU79745.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:KPU79745.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:KPU79745.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH902617; KPU79745.1; -; Genomic_DNA.
DR RefSeq; XP_014766227.1; XM_014910741.1.
DR STRING; 7217.A0A0P8XYQ0; -.
DR EnsemblMetazoa; FBtr0386000; FBpp0345910; FBgn0094020.
DR GeneID; 6499790; -.
DR InParanoid; A0A0P8XYQ0; -.
DR OrthoDB; 5477417at2759; -.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:EnsemblMetazoa.
DR GO; GO:0005819; C:spindle; IEA:EnsemblMetazoa.
DR GO; GO:0050811; F:GABA receptor binding; IEA:EnsemblMetazoa.
DR GO; GO:0055059; P:asymmetric neuroblast division; IEA:EnsemblMetazoa.
DR GO; GO:0098722; P:asymmetric stem cell division; IEA:EnsemblMetazoa.
DR GO; GO:0000132; P:establishment of mitotic spindle orientation; IEA:EnsemblMetazoa.
DR GO; GO:0045938; P:positive regulation of circadian sleep/wake cycle, sleep; IEA:EnsemblMetazoa.
DR GO; GO:0061172; P:regulation of establishment of bipolar cell polarity; IEA:EnsemblMetazoa.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00063; FN3; 1.
DR CDD; cd17117; RA_ANKFN1_like; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR039269; ANKFN1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000159; RA_dom.
DR PANTHER; PTHR21437; UNCHARACTERIZED; 1.
DR PANTHER; PTHR21437:SF1; WIDE AWAKE; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF00788; RA; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00314; RA; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50200; RA; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000007801}.
FT REPEAT 510..535
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 627..730
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1508..1609
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 34..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..295
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1244..1315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1386..1407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1471..1502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..213
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1273..1315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1388..1407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1477..1502
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1624 AA; 175679 MW; A77A42670B091B45 CRC64;
MEETAAGPAK KSGTTLSVDR AAFLLLRVRK VFKKKRQQRK ERQAQQSGAA AGGAGGGGGS
GSQSRTGSRK LPPPLLRSRT LPAIIVPGLP VVSLHTDKQT FQLEERLLGS KSRSGSASGH
RWSSLLTRGT NHSSGSGGGV GSGISGGNNA SSNNNNNNSH LANNNNTLMV KSLNLPKDDS
NLVYRRKSSG STPHHHQASH HHHHAHHQQH LQQQHAHLQH MQHLGDSSLF QLSDDFECHA
DGSLLLRIPA PHVVAARAYR LAARKRAAAS SESSTPLSRD PTLHEVPLAE ASGSGSSTTF
TRLAKLLHQS TALAGRSSLQ PPPAGDNVVH SLGLGLGLGL GEEAPRRLSW ERRKDSSALQ
RSASIDSFAE IVFSDLPRSS LAVTAPGGSV AGGPSPFSKR PSASSLYSTS TGCSFGSQAQ
AQLNVNYCDS AAGSGSSGGT GTGHHTAGGN GGSGGSGSRR ESMLSPSSTR RSKLTRIINA
LFSAVEHGHL EKARTILEST DVDVNSINSD GLSALDLAVL SNNRSMTRML LQHGAIEGSQ
FSVDTIGTKL NGLLKDAESR IHDLSGPEGL CPPIFASRPS ISSIIIGNSS ASVTGCTGSE
VEKQIGIWER RVKGLRRLQL GWDQARPPDA PASVVVDVTG DNSISVQILE PFEGAIGTKF
KVQWSTRADF NNVVGESELL EWVSFHGTMG AQCHISGLTQ GRRYFLRAAC GNVKGWGAYR
NSVPASVVPS TWRDLDNRED RFVGRHRILD NLFTAVRLAR PADVSELTLD PTSGQRRNPK
KKTTIKQLFS VTSKFQKTLR RGIYFSCIVQ CDDKVLVTSE DFPPVIEVDE TYPSALYMDY
YWLMKVACTW DDVKSLRTDM ERNLTSAVHF RTKLLSAVCQ MQSALGFTDL GQLYYKPLRD
AQGTVVLTCV QSVKSQKAVS ILNSRWLPVS KLQKKLGALH EDYTINELLI SSIGDQLHYQ
QAALQRLEPG LYLGYLKMQC SMDQIQVVVP VKTPNVLPHC KVRENSHITA EEWQVLHRCN
GDPLRLPLDF SAQEKEAAGG AATTEVQRLF LYDLTNAMHK LFASMNIKAA DAATHRLYDV
EVIEHSPDIS FLVVCPSAEA SCAVPGQSEL LLQRDDLASL SIQAFEMIHL RTYQPAIIQK
YARLSCILEL DTGLATHSLR EAFSSSELQA AKERLATLQE LSTSLNLVWK SVRWLMDVVA
YARNKSAQPS LAMREILDFT QQRQEESAVT NSASKQLLQL PIRESKFTKA GTGRGSWPGP
GTSEDQAQAK PEHSKSEQNL GLTAITPVEP SAKQMQHPQQ QQQPPQTLQQ QQQLLQVSTT
SEYAGSMCSD VSLRKNSGDS ISSTYTARSF YSAVDSASDG NSTNSVFAIP PSRSDDTLAD
ALRHSQTVAA QRKRTSSNIG SHPTPLITVH SSSSAPYLAG SSVSLRSGNG AFATDLEHKP
LKPATKAASS ANLREGGPYL KSTLAELRAV GGEEPVASTS KASSTKSLSR QSSEEDTASC
SSLNTEQTSG IIQVYTAYNT GLASGTSLKL HVTPKTTARE VINLVVKQLN MAVVLKGNNG
PIYGPETLEN FCLVAVIGAR ERCLRDDFKP LQLQNPWKKG RLYVRKKHEL LAAIEHSNRK
SHLI
//
