ID A0A0P8Y2Z0_DROAN Unreviewed; 557 AA.
AC A0A0P8Y2Z0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 28-JUN-2023, entry version 34.
DE SubName: Full=Uncharacterized protein, isoform B {ECO:0000313|EMBL:KPU81705.1};
GN Name=Dana\GF20504 {ECO:0000313|EMBL:KPU81705.1};
GN Synonyms=dana_GLEANR_2941 {ECO:0000313|EMBL:KPU81705.1};
GN ORFNames=GF20504 {ECO:0000313|EMBL:KPU81705.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:KPU81705.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:KPU81705.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH902621; KPU81705.1; -; Genomic_DNA.
DR RefSeq; XP_014761340.1; XM_014905854.1.
DR AlphaFoldDB; A0A0P8Y2Z0; -.
DR EnsemblMetazoa; FBtr0382897; FBpp0343073; FBgn0097510.
DR OrthoDB; 3107655at2759; -.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR CDD; cd00112; LDLa; 6.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 7.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24270:SF5; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 4; 1.
DR Pfam; PF00057; Ldl_recept_a; 7.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00192; LDLa; 7.
DR SUPFAM; SSF57424; LDL receptor-like module; 7.
DR PROSITE; PS01209; LDLRA_1; 4.
DR PROSITE; PS50068; LDLRA_2; 7.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..557
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006154305"
FT DISULFID 233..248
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 254..266
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 261..279
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 273..288
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 293..305
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 300..318
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 312..327
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 362..377
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 384..396
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 391..409
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 403..418
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 429..441
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 436..454
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 448..463
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 493..508
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 557 AA; 62608 MW; 0CA3B67FF92E62EA CRC64;
MYLSEFSIFL LVSLLWLCSG LCEITKFKME TRLDRYEKNG KKSFERLEDN KDTTFQSGGN
FKHLEGFNDS GDHQISNLFK TIASKLNSDL KVSSYHNEFS RKIPIDPTKT ISPDNINQHE
IPKFRNIGAQ KSLIEITGIK DSDRLSARGR DGLIGISKNK QMPFKLNLAV LVQDDPSQPG
ETYSNCPSQN ESDVSACKKV EDIMPKLQKD CEKMGSHVMC PRTYRCISKY WLCDGDDDCG
DYSDETHCGV RTNCTDDQFE CLNGFCIPST WQCDGENDCK DFSDEAHCNQ TSCTDEHFTC
LDGFCISLAF RCDGEPDCID NSDEHKCAAV INSCPDGEFK CREGLGGSGG PSGHCVLNRF
RCDGDNDCGD WSDEENCSRK PSLCTTNEYK CADGTCIPKR WKCDREQDCD GGEDENDCGA
VNSSHSLSCG NDEFTCKNGR CILRTWLCDG YPDCTSGEDE VECHLQCDLG QFLCPTIQNE
TNHKICVHQK HICDGYRDCP SGEDELNCPK QQKCLDPMQC EQLCIKTSLG IDECACRLGY
LMDQNRIKWT YVLVRLG
//
