ID A0A0P8Y6V2_DROAN Unreviewed; 8866 AA.
AC A0A0P8Y6V2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Uncharacterized protein, isoform F {ECO:0000313|EMBL:KPU77129.1};
GN Name=Dana\GF11157 {ECO:0000313|EMBL:KPU77129.1};
GN Synonyms=dana_GLEANR_11226 {ECO:0000313|EMBL:KPU77129.1};
GN ORFNames=GF11157 {ECO:0000313|EMBL:KPU77129.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:KPU77129.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:KPU77129.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR EMBL; CH902619; KPU77129.1; -; Genomic_DNA.
DR RefSeq; XP_014762550.1; XM_014907064.1.
DR EnsemblMetazoa; FBtr0381826; FBpp0342089; FBgn0088197.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd21189; CH_PLEC-like_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR CDD; cd00176; SPEC; 18.
DR Gene3D; 1.20.58.60; -; 30.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 1.
DR Gene3D; 3.90.1290.10; Plakin repeat; 11.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF02187; GAS2; 1.
DR Pfam; PF00681; Plectin; 1.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF00435; Spectrin; 17.
DR Pfam; PF21020; Spectrin_4; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00243; GAS2; 1.
DR SMART; SM00250; PLEC; 31.
DR SMART; SM00150; SPEC; 37.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF143575; GAS2 domain-like; 1.
DR SUPFAM; SSF75399; Plakin repeat; 14.
DR SUPFAM; SSF46966; Spectrin repeat; 31.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS51460; GAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 160..283
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 295..400
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 954..1012
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 8425..8460
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8461..8496
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8501..8573
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2887..2912
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2938..2963
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3003..3037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3147..3277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3316..3339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3363..3459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5624..5685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8272..8365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8600..8633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8645..8866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 511..595
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1094..1121
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5300..5331
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5446..5473
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5706..5769
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6005..6032
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6329..6465
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6549..6576
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6869..6896
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 7604..7669
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 22..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3016..3037
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3151..3184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3316..3331
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3363..3382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3384..3415
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3417..3440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5657..5685
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8302..8316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8317..8338
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8339..8353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8600..8630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8648..8673
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8681..8790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8800..8853
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 8866 AA; 997494 MW; 37E9FB567552A3FF CRC64;
MTSHSYYKDR LGFDPNEQQN EHSHLHSSNS NSNSNSMKRS SSRQTTHHHQ SYHHATTSSS
QSPARISVSP GGNPGNNGTL EYHQVQREQR DRELYSNNHH HSHHHQQQSH HHRHSSGNTS
SPLYESSPAA PKKAKHSSTQ PQPQGGYEDA LTQFKDERDA IQKKTFTKWV NKHLKKTYTM
LHVCVTTNGI PCCSQSANRR VVDLFEDLRD GHNLLSLLEV LSGEHLPREK GKMRFHMLQN
AQMALDFLRY KKIKLVNIRA EDIVDGNPKL TLGLIWTIIL HFQISDIVVG KEDNVSAREA
LLRWARRSTA RYPGVRVNDF TSSWRDGLAF SALVHRNRPD LLDWRKARND RPRDRLETAF
HIVEKEYGVT RLLDPEDVDT NEPDEKSLIT YISSLYDVFP EPPSIHPLFD MESQRRVHEY
RDLAQQFIYW CREKTAYLQE RSFPPTLIEM KRLLSDLQRF RSEEVSARKR EKSKLIQIYK
ELERYFETVG EVDVEAELRP DAIEKAWYRM NTALQDREVI LQQEIERLER LQRLADKVQR
EIKHVDQKLT DLETRIVEEG RRIERLHPVD AKSIVEALET EIRHLEEPIQ DMNQDCHVLN
EGRYPHVSEL HKKVNKLHQR WAQLRTNFHT NLVQKLSGLK YPVHETTVTR QTRMVVESRQ
IDTNPHFRDL QEHIEWCQNK LKQLLAADYG SDLPSVKEEL DRQQHEHKII DQFHSKILND
ERQQTKFSGD ELALYQQRLN QLQKVYAELL STSTKRLSDL DSLQHFLGQA SAELQWLNEK
EQVEISRDWA DKQLDLPSVH RYYERAFGNG DENLMSELEK REMHFATILD RGEALLNQQH
PASKCIEAHL TALQQQWAWL LQLTLCLEVH LKHATEYHQF FGEIKDAEQW LAKRDEILNS
KFSQSDFGLD QGETLLRGMQ DLREELNAFG ETVATLQRRA QTVVPLNKRR QPVNRQGPVQ
AICAYKQQGQ LQIEKGETVT LLDNSGRVKW RVRTSKGQEG SIPGACLLLP PPDQEAIDAA
ERLKRLFDRS VALWQKKHLR LRQNMIFATI RVVKGWDFDQ FLAMGPEQRT AIRRALNDDA
DKLLSEGDPN DPQLRRLRRE MDEVNRLFDE FEKRARAEEE SKQASRIFTE ECIAIKSKLE
DMARELDQII LAPLPRDLDS LEHVLEIHAD YERRLHLLEP ELKHLQETFR TIALKTPVLK
KSLDNLMELW KELNTQSGLH KDRLKLLEAS LAGLEDNEHV ISELENELAK HQDLPSTAEG
LQQVFKQLTH MQDVITQQQP QMDKMNDAAD QLGRMGVPTK VLGDLKRLHS NVERLNTRWS
AVCNQLAERM RSCETAIGLM KNLQSSVQVE ESWVDGTTER LSAMPTATSA YELDKLLGAA
IERKPKIENV NVAGGRLIRE AKIYDSKCLR FVDWLLEARP SFSPPRRDLR PADSDPGATQ
YYSQRLDNLN TKYDRLLEQL SQRLKTAIEV NGSDGLQYAE SLQKPLKTFR VDFSAGSVPT
GDGYAARPED LYTTTYSTTQ FSSTKTTKSS TKSVYSSDGL DAASQEVITS NLPPSQIQFN
EIRTLKRSQQ LGGNSVLDIA GIRDPRTGRV LTIGEAIQLR ILDVRTGEML VGDRRISLEQ
AAEQGLIDAQ LARQLLQPGA GRDASGRELS LLEVIQREIN EAESGYETAE KRIKVNSTVT
VESTGSPENP RNIADAITAG SVDTKTGLYR VKSGQTISLA EAYERGYLIR HESVTIKSNA
LCLSDAIAHG LVDGAGWIAD RNSGDKFRLD SAIANQLIDA GVREVVDAKR DTKITLQEAL
QSGVLNAKTG RYVNEVTKEK LTFAEARNRQ LIVKPYTLKD ICDLNLLDKQ AQITSPMRRE
KLSIMQAIEA GVLDGNNLKC ITKRKGELVT LQEAIADGIV LPAECKYRDF MTGELISIPE
AVERGLISSV AQRSIFDIDG FKDLRSSDYV SFNVALSRDL LRRKSTGFAL ETGRDSLVPL
EVAVGEGLVR QEVYEMFNRG IGVQNASGQE LSVFDLVYHN LIDPKTGYLL DPKTGETVPL
DTAIERKFIT AEGALLLSSL LNITLTTETV TRTINRYVTI RAGSQEPGDQ VLLTFTEAVR
QGFIDEERQL FKDPKTGNIY SVQQALNYGL LVPDSNQTVP EPTNRKKTKS TITIVTKQII
PEAEPIKLNT QHTKYVEKSV EIPISQELIK PQRVVSDFIN MEKSSYIEQN VTERQIMELP
PGGWRLKDAI EQRIFNPDTG VFHVQGTDRL VNFEECINKQ IINNLSVSII DPSTGDKISV
QSAFERDILD SYGNYTNSRK QVLGMRSAID EGKIILETVP ATRGSSQKTI LRITRVNNMP
DVLEVSTPLK DAPPKFVEVS TCQRELASPE PLQIAPGAIY DPSTALVIFT QSGETENIFD
AARQGLIDEQ LIKIVDPRTK QPISVTEAIA RSIYDPKTET ILDAEGQPVD LITATKLGLL
SVVGAPLVAA EGALRTVRFV TDPRTGEQIP VEVAYERGIV SRDQLQRGRS FDSEPSTTTV
EEKVVVLQRM RKIILKPKDA LRKGIIDEET CKILEDTNNF TNPQGEVVNI TEALNTGMID
GRRGKIIDPQ SNRVLNLRQA VEQKILDPEQ TNHILMPLAK SLSVPRLAAQ GLVDPKTQTI
VHPESGYPLS IHEAIVCEVL DPHSTLRKPE KCTLEAAIKK GIVDADESIF KYKNKNLNIS
EAIEARLFDP SYDQQKSKVD IPPVGMIFPV AVEKSLVEPS KRVVLHPSTK NALPIKQAID
ENFIMSIPYA PKKDAIEVVA AMERDLIDVA AQTITVPTTG ERLPLRQAME NGVLVVKQLS
DFVVTQKPIP KTEIMETVRA VHTVTTKTIE LMQGYVLISN NEVQNVNTGE VVSLEEAKEL
GILREESTTR ETKAAAGESP EAVQNLPTSS DQTVVVEERT QTVVVSSDTH KQEMQVISTT
QSTKENPAIP TVSEAETKVG KEPSKTLQNV KDAAKMGALG VIAAPVLAGG ALVSGVKSLI
KSVKSPAEDA KTTTQKPEKP QSSFIEQERR NVPEPQQVPS EVDNLLNETE NFISSTTANF
IINEQQQEKP QEVSRQEVES TNTLTTTTVT TITTSKTTTE TGDAEPVVVE DVKTTTTVET
TPVEPEIAKK PEDKPVDVQV TETITTVTRE ETISEPEKPT TKEPTPEKIV EKKPVEKPAK
KETTPAPVTK ETTPAPVTKE PTPEPIQKEK TPEPAPREAA QVPTKPEPQP RTAVKEEVPA
FEPPFTAPLA PFEEPKAETK ITEVTTEVQE PVSSTETITT ITTTVTTIDQ QPKEVTEVDK
SEPAKITEVE VEKPAVQEPI KDDKPSEILD EVSEEPTSSI VVEERVITVE EPTITESTVT
TTITTTTTTT SSEEQQPQET VVTEIVKEEP KKDTPQPEKT VVTEELVKEE PAKDASQPIT
EPTQTTETVT TTTTIIQEEK PQQPGDLEQI VQPPTSTNKH QSVVDFIQAE KNTQPSEGSK
VLQNVKDAAK LGALAIVGAP VLAGKALVDA LTSDKATKTG QPTTHVVTEI VEELPADISR
TTSTIVTKVT TTTTTTTTTG EGSPEDEARD VVELPISSAE PTIKREVPKT LPIGDAISQK
LISPDECQVI VDGEQQSQTV STLLKEEQLS PLDEVQIIDD KLIILQQISY LVDVDTELTP
EKLSELNIYD PENQYFIDPT TGQKISFQTL VFDMNIFNPE TILVKNFSTG KYETLTAALE
RPLLDRHTGH MVDPKTGKKI PFFECIERQW IIRADPEEQK PTGMENVTID PQTGQVILDD
GRVCSIVEAI NSGKLDIQSI SVRDPVSGEV IPLRMAIELG VVDMQAGTVI DIQTLKEIPM
ELAFQLGFLV PGARKPISLE AAVRKGLYDP ETGKLFDSES QNQVDVQKSI EIGLVDPKIS
LIVDTVTKKE VKLDCAIEDE LVVPSTGQIK DNKNNTLVPF DVGVQQRLVK TDSVTWSLPE
VLQREYYTPS TGKVLNPVTG EEILLQQAIE MGFVELDTTL VKDADHDKIV PGKEAAKVGL
LDTVRGTLSS PNISLDEAFV KGYLISTKKP LSLVDCLLRG LYDPSTAKFT IDDKQLDLKS
AIAQKLINPE ELVLLDPKTE SIISLTEAIA KGYLDPIGGY VINPYTSTKL SLHEALENRI
LIPPKRKRSL PDAVYRGLYD PKTGQFSNTV TREKLTTERA IRRGILDPDS TVVNVGSGQI
IPFGVATETG IVDSRQGTVK DQDDKSIDFK EAFDRGVLVE AKKPLRLIEA VVKNVYDEVD
GHFVDPKSGE KLNFAEALNT NLLDEHSVQI RDFKTGLYKQ LNLTHAKDSG VIDAQNSKLL
YNNQTMTLKH AFDIGILMDV NAPISIQRAI HQGLFDDKTG KLSDPRSGRQ ITLLEGMRSF
VINPHLSCYF DEQTETMYSL SETCRNGIIN RREGVFREPG SSSFVPLGEA LSLGLIVDIE
NAGFGLYELL SMGFYDTPTR KVLHPVTNRK LNLNEACVED VVSLSSSLVK HHETGKYLRL
ANAIKEQLID DNRGCYNLGN EQLDLQAARA RGFIVSNRRL LSLELVLRQQ LYRPETGKFC
DPTTGEYLDL IEAIHSGFID PATTVFKNQL TGKELPLGEA IENGDIDVSK GRVFDPKSKS
AYNYDVALAR GILVTVARPL TDRSEVVRRQ DSVELLGQTP VSVVISKPRE MSLEEAIRYN
IIDPKTALVR DFDSFKFLPY SVAVERGLVD TTKRTLVDPK ALYFAFDPTL IVYVREPITF
DQAAESKCLD LQTGILTYVP VSSATGNESA PAGDDSANDS LTVIETPKVY TLKEAASAGV
VDPDSALVKD LAKAKLVRLP EAFRKGLMDA NKANVLNTQT SKLCTLQEAY ESGLICTPKR
SFGLLEAITF NLYNPTNGCL VDPFQMHPDI IRRRKFTLAE AIGSGLVDPS STVVRDPSSG
VIVPLTAAIG SGLIDAAEGR LTDASDPKNN IDLVKAAEKG LLLPAEQRQA VFEKFNMCEE
NVNDLLKWVT TVEQKISSVG GPREKIDELR NQINALKQIK DEIESQQRPV ATCLEQIRQI
VLTGGDVLSA PEVTTLENSG RELRSRVDRV NDRTVRLLRR LEAGRDELTK LRSELDVFSD
WLQVARRTLE DKERSLSDLT RLPSQADSVR EFVSDVIGHQ ADLRFITMAA QKFVDESKEF
LAILNDFRTS LPERLPHVEP LSSAESPIRQ EVSLVSAQYK DLLNRVNALQ DRVSGLGGRQ
REYQDALDKA NEWLRSIAPR VSRIIAEPIA GDPKGVQDQM NEAKALHNEL LSSGRLVDNA
QQALDNLLRS LGGQLSPMEI NQLELPIADL KNNYQQLLDN LGEHCKNLDK TLVQSQGVQD
ALDSLVGWVN QAEDKFKLNL RPASLIKERL QEQIREHKVL LADLQSHQAS IDSVQISAKH
LLASASNARI AKKVESNLND VTGKFEKLYE KANKRGEFLD DVYNRLGRYL DDISNVEQRM
ASLQEALDSR ETSLLSTEEL ARRMNDLSRE KDHLAPQFED CVRNGKDLIG LRDVTDTGVL
RDRIKALESQ WRNINISIDE RAKLSKQKAE QQLAYEGLKD QVLSWLASTE ARVNGLPPVA
IDLDRIKQQH DELKPICKDY RDYAPTIDKI NDIGAQYDAL IRPESPARKR STYSPIKRAS
PLRRMSGDAR SPSPTKGGIL SPLSTGSSGF GSRRSSQDGF QLSELSPVQQ QLSEINNRYG
LIGVRLNDRQ HELDNLSEEL RKQYDNLKGL AQFLERIQRQ VPKESVSNKD EAERCIKQAR
KILEDMYEKQ SLLDTTKAQI KDILRRKSDV PGAEQLRLEN ENIQEKWKNL NDICKNRIAF
SEKLRDFLDT HGNLKSWLDS KERMLTVLGP ISSDPRMVQS QVQQVQVLRE EFRTQQPQLK
HFQELGHDVV DHLAGTPDAQ AVEVKLKDIL GKWEDLVGKL DDRANSLGGA ADSSKEFDAA
VNRLREALQN ISDNLDALPT DGDHQENLRK IENLERQLEG QRPLLADVEQ SAATLCNILG
DPASRADVNS RVAALEKQYL ALQKKLDTKK AETEASLRDG RHFAENCSKT LGWLGGELSN
LTDRLLVSAH KPTLQHQIDT HEPIYREVMA REHEVIMLIN KGKDLSDRQQ DRGVKRDLDR
IQQQWEKLRR EAVDRHTRLQ TCMEHCKKYS QTSEQFLAWL RTAEDKLSDL TPGVLSKAKL
ETRLRDLQTF RSEVWKHSGE FENTKGLGET FLTSCDIDKE PIKAELQDIR DRWERLNNDL
IARAHEIENC SRRLGDFNDE LRNLDHSLGR CEDRLAAHDA LGGAAKDPKL LERVKAIREE
LTNLSKPLQS LKALAKDISA EARAAGGDAD HLTSEVDGLA DRMSELQGRL DDRCGELQSA
ATAVSQFNEQ MKSLGIDLND LETEIEKLSP PAREIKIVQQ QLDDVGKIQH KLDRLVGRLE
DAERAADVLV DAGFAADTTQ TREQISTLRK TLGRLDNRVR DHEDNLQATL KALREFYDNQ
STTLDDIQDV SEEFKRMKPV GSELDQIRRQ QEDFRNFRER KVEPLAVNVD KVNVAGRDLV
RSAGSGVSTT AIEKDLEKLN DRWNDLKERM NERDRRLDVA LLQSGKFQEA LAGLSKWLSD
TEEMVANQKP PSSDYKVVKA QLQEQKFLKK MLLDRQNSMG SLANLGKEVA NHCEPAERAS
IEKQLNDLMK RFDALTDGAE QRELDLEEAM EVAKRFHDKI SPLELWLDNT ERAVKSMELI
PTDEEKIQQR IREHDRLHDE ILGKKPDFTD LADVAAQLMH LVSDEEAVNL GEKVRGVTER
YTGLVDASDN IGALLSESRQ GLRHLVLSYQ DLVAWMESME AELKRFKSVP VYAEKLLEQM
DHLLELNENI AGHASNVEST VESGAELMKH ISNDEAIQLK DKLDSLQRRY GDLTNRGGDL
LKSAQNALPL VQQFHEAHNR LVEWMQSAEA ALAPSEPRQS DVLRLEGELA DMRPILDTIN
LIGPQLCQLS PGEGAATIES IVTRDNRRFD SIVEQIQRKA ERLHLSNQRA KEVTGDIDEL
LEWFREMDTT LREADPPAME PKLVRAQLQE HRSINDDISS QKGRVRDVTA ASKKVLRESP
QSENTATLRE KLDDLKEIVD TVAQLCSERL GILEQALPLS EHFADSHQGL TAWLDDMEQQ
ISRLSMPALR PDQITLQQDK NERLLQSIAE HKPLLDKLNK TGEALGALVA DEDSAKINEI
LDTDNARYAA LRLELRERQQ ALESALQESS QFSDKLEGML RALANTVDQV NQLDPLSALP
QKIREQIEDN DALMDDLDKR QDAFSAVQRA ANDVIAKAGN KSDPAVRDIK AKLEKLNNLW
NDVQNATKKR GSSLDDILSV AEPFWKQLNS VMKTLKDLEE TLSCQEPPAA QPQDIKKQQV
ALQEIRHEID QTKPEVEQVR RHGSNLMNMC GEPDKPEVKK HIEDLDNAWD NITALYAKRE
ENLIDAMEKA MEFHETLQNL LKFLTKAEDK FAHLGAVGSD IDAVKRQIEQ LKSFKDEVDP
HMVEVEALNR GLQRQAVELT ERTSPEQAAS IREPLSVVNR RWEALLRGMV ERQKQLEHAL
LHLGQFQHAL NELLVWINKT DGTLDQLKPI PGDPQLLEVE LAKLKVLAND IQAHQNSVDT
LNDAGRQLIE TEKGSLEAST TQEKLRKLNN EWKQLLQKAS DRQHELEEAL REAHGYIAEV
QDILGWLGDV DAVIGASKPV GGLPETATEQ LERFMEVYNE LEENRPKVET IQAQGQEYIK
RQNQMKVSSS NLQHTLRTLK QRWDAVVSRA SDKKIKLEIA LKEATEFHDT LQAFVEWLTQ
AEKLLSNAEP VSRVLETIQA QMEEHKVLQK DVSTHREAML LLDKKGTHLK YFSQKQDVIL
IKNLLVSVQH RWERVVSKAA ERTRALDHGY KEAREFNDAW SGMMQYLQET EQVLDQIIEE
ATASKEPQKI KKYIGKLKET HRQLGAKQSV YDGTMRTGKN LMERAPKGDR PVLDKMLLEL
KEQWTRVWSK SIERQRKLEE ALLLSGQFSD ALGELLDWLK KAKSRLNENG PVHGDLETVQ
GLCEHHKHIE QDLQKRAAQM QGVLKTGRDL ERSGNNPEVG RQLDEMQSIW EEVKNAVAKR
GDRLQVALVD AEKLNARVQA LFDWLDHAEH KLRYAKNAPD DEKVSREMMD IHMEFMKDLR
VREREKTETF EYAEDIIGKA YPDAIPIIKN WLSIIQQRWE EVRQWAINRE SKLEQHLQSL
KDLDDTIEEL LAWLSGLEGT LLNLKHERLP DEIPPVEKLI EDHKEFMENT ARRQNEVDRA
CKPRQLPPGA RKPSRSGKTP VRGSSHDLRE TSPDGTLRRQ SFKGSRDQGL NARKGSRVTP
TRDTPDRDRL PHYGPRFSPS TAGPELEFRS PRAKLLWTKW RDVWMLSWER QRLLYDHLLY
LKDVERARNF SWDDWRKRFL KYMNHKKSRL TDLFRKMDKD NNGMIPRDVF IDGILNTKFD
TSGLEMKAVA DLFDRNGEGL IDWQEFIAAL RPDWQERKPA TDSDKIHDEV KRLVMLCTCR
QKFRVFQVGE GKYRFGDSQK LRLVRILRST VMVRVGGGWV ALDEFLQKND PCRAKGRTNI
ELREQFILAD GVSQSMAAFT PRRSTPNAAA TASSSPNAQN GGSSNLPPYM SGQGPIIKVR
ERSVRSIPMS RPSRSSLSAS TPDSLSDNEG SHGGPSGRYT PRKVTYTSTR TGLTPGGSRA
GSKPNSRPLS RQGSKPPSRQ GSTLSLDSTD DHTPSRIPQR KPSTASTTSG TTPRPARLSV
TSTTPGSRLN GTSTITRKTA SGSASPAPTS RPSRIPIKIP SFDSKSTSPT SSTTNPTSLG
RNISGSSTPS GMQTPRKSSA EPTFSSTMRR TSRGTTPTEK REPFRL
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