ID A0A0P8ZJG4_DROAN Unreviewed; 8952 AA.
AC A0A0P8ZJG4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Uncharacterized protein, isoform L {ECO:0000313|EMBL:KPU74934.1};
GN Name=Dana\GF19006 {ECO:0000313|EMBL:KPU74934.1};
GN Synonyms=dana_GLEANR_20542 {ECO:0000313|EMBL:KPU74934.1};
GN ORFNames=GF19006 {ECO:0000313|EMBL:KPU74934.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:KPU74934.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:KPU74934.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr
CC protein kinase family. {ECO:0000256|ARBA:ARBA00006692}.
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DR EMBL; CH902646; KPU74934.1; -; Genomic_DNA.
DR RefSeq; XP_014759328.1; XM_014903842.1.
DR EnsemblMetazoa; FBtr0384833; FBpp0344846; FBgn0096018.
DR GeneID; 6501771; -.
DR KEGG; dan:6501771; -.
DR OrthoDB; 5303642at2759; -.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd00063; FN3; 39.
DR CDD; cd00096; Ig; 3.
DR CDD; cd05748; Ig_Titin_like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 78.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR14340:SF24; -; 1.
DR PANTHER; PTHR14340; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR Pfam; PF00041; fn3; 39.
DR Pfam; PF07679; I-set; 36.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 39.
DR SMART; SM00409; IG; 37.
DR SMART; SM00408; IGc2; 29.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 21.
DR SUPFAM; SSF48726; Immunoglobulin; 39.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50853; FN3; 39.
DR PROSITE; PS50835; IG_LIKE; 27.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 9..102
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 122..212
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 231..324
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 338..429
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 441..536
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 546..638
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 643..731
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1753..1845
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1848..1932
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2126..2223
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2226..2324
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2328..2418
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 2426..2521
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2527..2622
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2724..2821
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2827..2922
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 2926..3018
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3026..3121
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3127..3222
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3226..3315
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3323..3417
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3424..3519
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3523..3613
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3621..3714
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3720..3815
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 3819..3908
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 3912..4009
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4015..4110
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4114..4204
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 4212..4305
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4311..4410
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4511..4604
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4610..4705
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4709..4800
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 4806..4899
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 4905..4998
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5002..5092
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 5100..5195
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5201..5295
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5397..5490
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5496..5590
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5689..5783
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5789..5884
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 5983..6081
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6087..6182
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6186..6277
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 6284..6378
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6384..6478
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6484..6579
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6573..6670
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 6679..6773
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6779..6875
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 6975..7069
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7075..7170
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7176..7271
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7277..7355
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 7469..7564
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7570..7665
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 7670..7759
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 7764..7857
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 7862..7955
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 8012..8267
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 8335..8423
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 8460..8535
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 8651..8739
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 8759..8849
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 8858..8932
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 835..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1052..1220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1253..1276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1402..1491
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3206..3228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3995..4019
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4983..5002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6372..6395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6481..6506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6759..6783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8577..8635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..917
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 935..951
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..985
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1057..1075
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1076..1103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1254..1273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1456..1473
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8582..8618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 8041
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 8952 AA; 1002831 MW; 25E3CA1B0A37E94F CRC64;
MGVAEDFAPS FIKKPQLHQE DDGNRLIFEC QILSSPKPDI EWFRSDNKLV EDERTKFKIQ
PDGNNNYTVV LELDDVVEAD AGLYKVKAKN KSGEVSASIN LNFTQGMFSL HENEGQIDGF
APTFAKKPAI RQEEDGKRLL FECRVNADPI PIIKWVHNGT DVKESSRHKL TIDKDGHSYF
ATLEIMNVTV EDAGKYKVNA KNELGESNAT ISLNFDSDEA PIPESADGIK PTFTERPVIR
QSEDGGNVTF ECRCVGEPMP TVTWSHGETI LSEGNRYKMS LTMDQKLYYM ACLEISCVVS
TDQGEYRALA KNRHGSGVAA INLNFESGSK KIPDGKSPRF PKKPTIRQEE DILIMECILE
AHPMPEIVWY CSDTEIINNQ RTKMTRKVIT KDSYSLTLEI KNPTKDDGGS YRCNAINMYG
ESNANIALNF QGASDVNGFA PSFIEKPRII PNESGTLITM KCKCKAKPEP TVTWYRGQEV
VEKNQKIKIN IIVVAEDTYE LTLEIKDPGA SDGGTYRCNV KNEFGESNAN LNLNIEAEPE
LEGEGPTFIE KPRIVSENNG KLVIMECKVK ADPKPDIIWY RNGMAIQEIN KIKMSMEQRG
DQYYIKLELL DPQLDDSGIY KCNIKNSLGE LNANLTLNIE IVPVIKEKPK IIKIIKKRSV
VIECTVASKF QPKCTWYKEA NVVKESTRHV YLVEKIKDGE FAVKLEINDV EESDKGAYKV
VASNEKGEAV SQVVNLIDIP EEDRKPSKPE ILKKLVDQKV TESKMFELLI KLTQSDRKCK
VEWYKGNTLL RETKDITTTF DGTIARLTFS TAKSEHTSNY KVIVINEVGK DESSCKVTVE
KKDKKKDEKP KNNDASDANK ELKEEENKNK TPEVPEDNLE PASKAEEIKK MKSQESKEKT
KLEKEEDKTK IFETQNKADK PVTKLQPKII TKNTEKEVTN VKTDEGKESN EVSSAKIIPQ
SISKKVKSEI PEVNNQQSDL NKNKKTELSS STDTENEWNE PQAAEEKILK KAERKASIIS
VKEDDSLEVR RQSIINCKEE TSIEDSKIEE VRKSSLVVQE SKTGSRRSSI IEKNSLEQVD
TKKLDANKNP QEIKEEIPKL KPSALRRNSK PIEAQKPSED LPHLRKASIA QPKEESKPEA
PKAKTKPKAK SKPKYEELPE IPDYERPVLE KYEKSEFKPS DFGRDVEIPS KMEKPILDGN
KKEPQPESPK NDLLKKTAII EKTPEEKKEL KIGKGKLAYE DDGQDGVSLK PVIIEPQNDS
TDGNSQESKQ AERTSLLDTI KQRRRSSIRN LMTKEPIQNE SFLGVVLKPV IKDSKEQTLP
QQAKQLTKAN ILEKLSSTKA IKAHISDLKK PEAVATLIDD YEVPVLEKYD PVKLDNSKSE
VPTPGIITPD TKSSVVKVPV EFPKEEKPKM TKIQQPAAGE PPKIEVIREK RPSLAPEPPS
RRGSLIPPAD MGRRPSLIIN DEKKLRPGEV MDTRLLRPGE VGEGQRRRPS IDVRRPSVQD
LEDLINKPST PLRDVGDGGP PSIVDVQESY SVVEDSTAYL TVGVEGSPAP TFKFYKGVSE
ILEGGRYKFL TDGQTNTITL CMRKCKPNDE GKYKIVVSNI HGEDSAEMQL YVSDSSGMDF
RAMLKKRRYQ KWDKDEQDPN WGDLKETEKP LPALKKVERK VESFLSPLID QFAKEGKDKK
VIFEARFSKP NCKPKWLFRK DEVFTGSKFK FKQENDTYQL IIMTPKVEDT GKYTIEIGGV
SSTAFLNVEE ADPTYTFTKT LKKKLEGFTE HETTLECAVS SSMANVHWFK DNTKIESDDP
RYLISKDING NLKLIIKESL IEDSGLYRCQ LDKQSDKTEC NLRVVEYPYK FVKVLKSQQC
VEKDTVTLAC EIDDARGEVQ WFRNDEEIKA DKRIQIIKDG RKRKLVIKDC KVTDAGRFKC
TTNADKTEAE IIINYQNRFN KKLKDTDAVE REKLVLDIEL QDQTAPCNWK FNGDPIVPNE
RIEIKNLGGG KHQIIFNNLE MSDEGEIECE SGQITSKCHL SVRKGESRPN IDCPDEFTGP
ISAPVVIEVP FKVSGTKQSP VEAKLFKDGK PLPVKDVDVC IADDKVIFKI KKPSRDLSGP
YQIKLSNGQG EDSKDVHIIC QDVPQPPQDV DITDVYQTSC IVNFKPPTDD GGTPIIKYLI
ERQDISKKQG WEPVVEVLPS EPLVKKIDDL VPKKQYRFRL RAVNKIGPSD PATFKSSILA
KDPWDEPGKP QSVDLIDWDK DHADLKWEAP ENDGGDLITS YILEYKEKFS NDWVTSKEVD
GQTRAATVDG LKEGQQYEFR VRAVNRAGPG EPSDKTKSII AKCRFVKPFL VGDGLKNITV
KKGQTIRYDI KYDGEPEPTA TWLKGHDNIK FDNQRISLEQ LERNSSITVK KAVRKDTGRY
KLVLSNSSGT IESEAQVVVL DRPLAPGGPL EPDEIRANHI KMKWKHPEDD GGCEITGYTL
ERMDEETGRW IPAGEVGPNE NSFDFKGLTP NKKYKFRVKA INKEGESEPL ETSDAILAKN
PYDPPSPPSQ PIIDDYDNKS VSLKWNRPPS DGGRPITHYV VEMKDKFSPT WSEVAQTEDP
TPKCSVEGLK EKMIYQFRVR AVNKAGASEP SQPTDNHLCK HKNLKPQIDR STFKRVTIKS
GRTHKWSVDV IGEPVPTLCW SWRDDIPLNN GDRIKIENVD YHTDFAITNA LRKDSGFYTL
KAENCNGIDR ETVELVVLGK PSSPKGPLAV GDVSATGCKL QWKKPDDDGG VPIKEYVVEK
MDTATGKWIR VGRSPGEKEP PSFNVTGLSP GSEYMFRVSA VNEEGESEPL TSLVGVVAKD
PFDEPNKPGA PEVIDHDNES VSLKWMPPNN DGGAPIQKYI IEKKDKNKPE WEKAIEVSGD
KLEAKVGGLQ EYGEYQFRVI AVNKAGLSPP SDASVPQIVK YKKLKPRIDR TNLKPLLIRA
GKPIKYDINV RGEPAPTITW YQNDLELKPN ELPNNSEIKN IPYNTKISIL DAVRKNTGTY
KIKAVNEHGE DEATVEVNIL GPPGKPMGPL AVTDITKDSC KLKWKKPNDD GGVPITAYQV
EKFDKKQGRW VPVGRSSGND TEFDVKGLQE GHEYQFRVRA INEEGESEPL ETDGSIIAKN
PYDAASKPGT PIIDDYDEHM VKLRWEPPKS DGGVPIVGYI IEKKDKFSPI WDEVLTTNSP
APEAVVKELT EGNVYQFRVR AVNKAGASEP SDATGHHLSK PKNLKPSINR EKMNSIKVRA
GQAVKFDIDV KGEPAPSLTW IFKEKELLHT GKVRLENEDY NTKLTLLDTS RKDSGQYRLR
AENINGVDEA DVEVIILDKP SKPEGPLEVS AVHKEGCKLR WKKPKDDGGV PLTGYVVEKM
DTATGKWVPA GSVDSEKTDI EIKGLDPNHR YQFRVKAINE EGESESLETD SAITAKNPFD
VSAPPGLPEL EDWDENHVKL KWEPPIRDGG SPISCYIVEV MDKDTGEFVK ALETDSPICK
GIVKKLDEGQ QYKFRVRAVN QAGPSDPSEQ TNWHTAKPRY LKPHIDRTNL KPVIVKTGLS
ISLDIIIKGE PAPKVQWLFN GNPLINQKDG VQIDNIDYNT KFFVMRAERS QSGKYTIKAI
NEVGEDEAEL EISVLGKPAK PEGPLHVNDV TKHSCKLKWN KPKDDGGAPI DYYEIEKLDP
HTSQWLPCGK STEPEAKVIG LQEGKQYKFR VRAVNKEGES EDLETEKPII AKNPFDEPDK
PGRPDPTNWD KDFVDLAWDP PKNDGGAPIQ KYIIQMRDKS GRSWVDAATI AGDKTKGTVT
GVQEGHEYEF RVVAVNKAGP SDPSDVSKSV IAKPRHLKPH IDRKNLQKKI MRNGQLLHMD
ANVKAEPPAK ITWVYNGAEI KNSDKIKIEN EDYKTTFVIP KVKRTDCGIY TVTAKNDSGS
DTVQVELEVL CKPSKPKGPI AVSAVLAESV HLKWDKPEDD GGEPIEHYIV ERMDTETGRW
VPVQTTKTPE ADVTGLTEGK EYLFRVKAVN SEGESEPLVS DVPTKAKNPF DPADTPGKPQ
ITDWAANFCD LKWRAPEDDG GAPITSYIIE KKDPSTGKWQ KAFESNTPDC KARVNDLIEG
KKYQFRVKAV NKAGQSKPSE PSDQLIAKDR FAPPKIDRTH IKDVTIKAGQ PIRYDIKVSG
EPPATKAWLH NKARLNSDDT DYNIDIESYR TKLAVPFAKR LHSGKYTLKA ENESGRDEAS
FEVIVLDKPG TPEGPLRVSD VHKEGCMLKW NPPLDDGGLP IEYYIVEKMD TETGRWLSSG
RFKEPLAEVC NLEPGHEYKF RVLAVNTEGE SNPLIGEQPI IAKNPFDEPG KPGIPEASDW
DKNHVDLVWR PPINDGGSPI SSYIVEKREK GTDKWIKGAE VTAPELGEEC RASVNNLDEN
CEYEFRVKAV NAAGPGEPSD SSKFVITKPR KLGPKIDRRN IRTYNFRAGE PIFLDINISG
EPAPDVTWQQ NNKSVQSTSE YHIENIPYNT KYINNNPNRK DTGLYKIIAL NLYGQDQVEL
QINIISKPGK PEGPLEVSEI YKDGCKLKWK KPKDDGGEPI ECYLIEKFDS DTGIWLPVGK
TEVPEYNVDG LVSGNEYQFR VKAINKEGES EPLETFGSII AKDPFTVPSK PGVPEPTDWT
ANRVELSWLE PANDGGSPIT GYLIEVKDKY SPLWEKSLET SSPTPIATIP GLIEGNEYQF
RVVALNKGGQ SEPSDPSKTF IAKPRYLAPK IDRRNLRDVT ISSGTALKLD ANITGEPVPK
VEWKLSNYPL QSSKNVTIET PDYYTKLVIR PTQRSDSGEY LVTATNSSGK DSVLINVVIT
DKPTPPKGPL QISDVHKEGC HLKWKRPIDD GGTPIEYFQI DKLDSETGCW VPCCRSTEPQ
VDVSGLTPGN EYRFRVSAVN SEGESLPLLG EDAVVAKNPF DEPGKPENLR ATDWDKDHID
LAWTPPLADG GSPIIGFIIE KKDKYGKWEK AVEVPANQYE ARVPDLTEGQ AYEFRVSAVN
AAGPGEPSDA THSLTAKSRN KPPVIDRSNL IEVRIKAGQG FGFDCKVSGE PAPKTKWLLK
NKEIHTKENL KITHIDYNTK LKVNGATRSD SGLYTVEAEN ENGKDSANVK VTVIDKPSPP
NGPLKVTDVA AEGCTLHWNP PDDDGGQPID SYSLEKLDEV TGRWIPAGET DSPITNIRIK
GLTPGHKYKF RVRAKNRQGV SDPLTTPHVI EAKNPYDEPT KPGIPIITDF DKDFVDLEWT
RPDSDGGSPI TGYIIEKRDK YSPNFEQIVE INGDITNGHV PGLIEGVKYE FRVRAVNKAG
LGTPSDSTEP HLARSKNLPP NIDRNFMTDI KIKAGNVFEF NVPVSGEPIP SKEWSHDDSM
VINTDRVKIT NYNDRTKLRT IDAKRSDTGS YTLVARNING VDKHTVKLIV LDIPTAPEGP
LRHNDVSKSS AMLSWRPPRD DGGSEITHYV VEKMDNEAMR WIPVGESSST EIRADNLIEN
HEYNFRVRAV NKQGQSQPLV TSQLITAKDP YSHPDKPGQP IAVDWGKDYV QLEWTAPKKD
NGAPISSFIV EKRPKFGLWE RALMVPSNEL TAYIPELTDG GEYEFRIIAV NRAGPSDPSD
PSTPIICKPR FLAPYFDKNS LNDITVHAGK RLGWNLPIEA SPKPSIKWLH NGKETASTRG
ESSLFQNELT FEIASAIRGD EGRYTLILKN EHGCFDASAH VTVLDRPSPP KGPVDITKIT
RDGCHLAWNV PEDDGGSPIL HYVVEKMDLS RGTWSDAGMS THPVHDVSRL VHRKEYLFRV
KAVNAVGESE PMEAANSIIA KNEFDEPDAP GKPNIIDWDR DHVDLQWAEP KNDGGAPLEE
YIVQKKEKGY PYWTNVLHVP PNQNNAKVSE LTEGQEYEFR VIAVNQAGQS EPSEPSDLIK
AKARYLAPKI LSPLREIRIK AGLIFHIDID FIGEPAPEAI WTHNNNPLIS NDKSTITSIG
HHTVVHTVNC QRTNSGIYHL LLRNDSGIDE GSFELIVLDR PGPPDGPMQF EEITANSVTV
SWKPPKDNGG SEISSYIIEK RDLTHGGGWV PAVNYVNAKY NHAVVPRLLE GTKYEFRVMA
ENLQGRSDPL TSDHPIIAKN QYTVPGIPGK PEIADSDKDH ISIKWKQPIS NGGNSIIGYD
IERRDVNTGR WIKINGQPIP ITEYQDDRVS TNHQYQYRVS AINAAGNSKP SEPSSIFHAR
PLREKPKLYL DGLVGKRLKV RAGEPVNITI PISGAPTPTI EWKKDSQNLA EGKRVSSDTN
SERSVFRIDD SRRQDSGKYS IIASNDFGID KADIEIIVVD KPTPPEGPLC YTKTAPDHIS
LQWNPPKDDG GSEITGYVIE FSEFGTDDWK PVPGYCPKTN YTVKGLLEGR KYIFRVRAEN
IYGSSDALEG NPVISKSPFD PPGPPSQPSI TAYSPNSASL EWHPPDYCGG KPISGYIVER
RERGGEWIKC NNYPTPNASY TVPDLRDGVR YEFRVTAVNE AGPGQPSKPS DSVTAKLQCY
CPDPPEPPKP DRISKDSVTL SWRPPRNDGK SKIKGYYVEM RPKNGNDWKP VNELPINSTV
YVVPHLKEGE EYLFRVIAEN DVGRSSPSKP SQPIMIEEQP NKPSMELGSV RDIVCRAGDD
FSIHVPYMAF PKPNASWYSN DTILDDDNRV HQHLTDDAAS IVVKNSNRCD SGQYRLQLKN
PSGFDTATIN VKVLDRPGPP SNLRADEFSG DSLTLYWNPP KDDGGSPIQN YIIEKKEAHS
PTWNKVSSYC TVPFVRIRNL TINKEYDFRV IAENKYGQSD SANTSEPIKA RHPFDVPNAP
GIPRGIDSSE DSITISWSKP KHDGGSPISG YIIEKRLLSD DKWTKAVHAL CPDLTCKIPS
LIENAEYEFR VAAVNAAGQS AFSASSDLIF CRRPPNAPKI TSDLSIRDMT VIAGEEFHIT
VPYNANPRPT PSWTLNGIDV APNDRVHFNT DDYISVYYNK FAKRCETGAY TITLTNTKGA
DTASCHITVV DRPAPPQGPL NAYDITPDNC TLAWKTPLDD GGSPITNYVV EKLDPSGTWV
KVSSFVRNTH YDVMGLEPQH KYHFRVKAEN QYGLSDPLVL SDPIVAKHQF TVPDEPGQPK
VIDWDSGNVT LIWTRPTSDG GSRIQGYQIE YRDIVNDSSW NTYDFLIKDT KYQLYNLANG
TEYEFRIKAK NAAGLSKPSP PSLRFKLKGK VSAPSPPETP QVTKVGKNYV DLKWEKPLRD
GGSRITNYVI ERRDIGGALW VKCNDFNVLD TEYTVTSLIE MGDYEFRIFA VNSAGRSEPS
LCTMPVKVCE VIGGEKPEWI TRLQNRVVPH GKDCTLKCEA IGKPSPISRW LRNGKEIQMG
VSRFSCDSID GVYRLHISNV QAGDEGNYTC EATNSLGFVH TTGFLKIGSP PIINKCPKEL
YLPEGDNTKI KIYYSGDQPL SVKITKNNEV ISDDNDESHF KFTIFDEYAA LFIRDIVKND
AGLYQIEFTN DSGSAIGQFD VRITGIPSSP TGPMGVSNIN KHSCIVTWRQ PAHDGGLRVT
HYIVERKDVA SPHWITVSST CKDTSFNVQG LIENQEYIFR VMAVNENGMG PPLEGLNPIR
AKAPIDPPSP PGIPQILEIG GDFVHLEWTK PESDGGSHIQ GYWIDKREAG SDTWQRVNVT
ICSATQINCP HLIETRQYEF QVFAQNAAGI SKASSASQTV KIVDPKAASP PFVVKPLRDA
NCIQNHNAQF SCTISGIPRP TITWYKGARE ITNGARYHIY SEGDNHFLSI NDIFGEDADE
YVCRAVNKAG AKSTRAALVI MTAPKLNVPP RFRDTAYFDK GENVVIKIPF TGFPKPRINW
VKEGENIESG GHYAVEVKER HAVLIIRDGS RLDSGPYRIT AENELGSDTA IVQVQISDRP
DPPRFPLIEN IGTDSLSLSW KSPVWDGGSD ITNYYVERRE HPLASWIRVG NTRFTLMAVG
GLNAGKEYDF RIFADNVYGR SEPSNTSTLI KTKEAIKKKP TERKWELDAN GKKVRGKADG
QIKDYDSYVF DIYSKFVPQP VEISQQSVYD KYDILEEIGT GAFGVVHRCR ERSTGNIFAA
KFIPVSHLIE RDLIRREIDV MNQLHHQKLI NLHDAFDDDD EMVLILEFLS GGELFERITV
EGYVMTEAEV INYMRQICEG LKHMHERNII HLDIKPENIM CQTRSSTNVK LIDFGLATRL
DPNEVVKITT GTAEFAAPEI VNREPVGFYT DMWSTGVLAY VLLSGLSPFA GDNDVQTLKN
VKACEWDFDE QSFNNISDDG KDFIRKLLVA NKEKRMTAHE CLLHPWLTGD HSNMTQAITR
DRYLAYREKI RRKFEDFEKY LLPIGRLSEY SSLRKLLMEK YKIHDTVFDR RQAAPRFVIR
PSSQFCYEGQ SVKFYCRCIA IATPTLTWTH NNIELRQSVK FMKRYSGDDY YFIINRVKLD
DRGEYIIRAD NHYGSREEVV FLNVQPLPKE QPRYRTESTP IRRRDPLPYT FWQEESESAP
SFTFLLRPRV MQARDTCKLL CCLSGKPVPS VKWYKDGREL SKYEYAMTHS DGVVTMEIID
CKPSDSGKYI CKATNCHGFD ETECVVIVEG EWVTPEQAEL AHNFLYSGDR KYIEQPLKPA
PPQIVTSRQL TSTSMQETSE TKNDENSNQS NLSNKKKYAA SSLKAPGSPS RSRSATKELI
LPPDDSLMFK PEFIVPLHDL NIHDGEQLVL SCHVKGDPEP QITWSKNGKS ISSSDIIDLK
YRNGVATLTI NEVFPEDEGI FTCTATNSIS AVETKCKLTI KALGKNISNL RVASKDNAPK
VVSHLESRYV KDGDAVTLAC RIIGAEHFDV VWLHNNKEIK PSKDFQYSKE ANIYRLQIAE
IFPEDGGTYT CEAFNDVGES FSSCTINVSV PGDEPKHPAF VRFPISVSIQ EGENVIFDCE
LDSEILNLIW VKDGKPIDET LSRYSFTKEN NIYSFSVSKC NMDDVGQYQA KAIARKGESI
CAFSVNIYNS EL
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