ID A0A0P9CIL3_9BACL Unreviewed; 372 AA.
AC A0A0P9CIL3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=AN477_15895 {ECO:0000313|EMBL:KPV42862.1};
OS Alicyclobacillus ferrooxydans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae;
OC Alicyclobacillus.
OX NCBI_TaxID=471514 {ECO:0000313|EMBL:KPV42862.1, ECO:0000313|Proteomes:UP000050482};
RN [1] {ECO:0000313|EMBL:KPV42862.1, ECO:0000313|Proteomes:UP000050482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TC-34 {ECO:0000313|EMBL:KPV42862.1,
RC ECO:0000313|Proteomes:UP000050482};
RA Hemp J.;
RT "Draft genome sequence of Alicyclobacillus ferrooxydans DSM 22381.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPV42862.1}.
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DR EMBL; LJCO01000069; KPV42862.1; -; Genomic_DNA.
DR RefSeq; WP_054970188.1; NZ_LJCO01000069.1.
DR AlphaFoldDB; A0A0P9CIL3; -.
DR STRING; 471514.AN477_15895; -.
DR PATRIC; fig|471514.4.peg.4865; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000050482; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000050482}.
FT DOMAIN 20..358
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 372 AA; 41266 MW; F4B066F766D768A5 CRC64;
MTVFGTRPEA VKMAPLVKVL EQNPFIESLV CVTAQHREML DQVLEVFNVH PDDDLDIMEP
SQSLGTITRK ALEGLETVIA QRKPDIVLVH GDTTTTLAAA LAAFYQQVKI GHVEAGLRTY
DKYSPFPEEM NRQLADVLTD LFFAPTSWAA GNLYREAKPE ENVFITGNTA VDAMATTVRQ
QYHHEVLDSI PDGTRIVYMT SHRRENLGEP LGNICRAARR LVDAHPDVHL IYPMHLNPSV
RETAVSVLGG HDRIHLIEPL GVIDNHNFMS RSTLILTDSG GIQEEAPSLG VPVLVMRDTT
ERPEGVEAGT LRLVGTDEEA IYNNGYELLN DEAVYQDMAG RKNPYGDGHA SERIAEAILY
HFGMGEKPAT FE
//
