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Database: UniProt
Entry: A0A0P9E0N4_9ARCH
LinkDB: A0A0P9E0N4_9ARCH
Original site: A0A0P9E0N4_9ARCH 
ID   A0A0P9E0N4_9ARCH        Unreviewed;       175 AA.
AC   A0A0P9E0N4;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   10-APR-2019, entry version 13.
DE   RecName: Full=Nicotinamide-nucleotide adenylyltransferase {ECO:0000256|HAMAP-Rule:MF_00243};
DE            EC=2.7.7.1 {ECO:0000256|HAMAP-Rule:MF_00243};
DE   AltName: Full=NAD(+) diphosphorylase {ECO:0000256|HAMAP-Rule:MF_00243};
DE   AltName: Full=NAD(+) pyrophosphorylase {ECO:0000256|HAMAP-Rule:MF_00243};
DE   AltName: Full=NMN adenylyltransferase {ECO:0000256|HAMAP-Rule:MF_00243};
GN   ORFNames=AOA65_0890 {ECO:0000313|EMBL:KPV64674.1};
OS   Candidatus Bathyarchaeota archaeon BA1.
OC   Archaea; Candidatus Bathyarchaeota.
OX   NCBI_TaxID=1700835 {ECO:0000313|EMBL:KPV64674.1, ECO:0000313|Proteomes:UP000050312};
RN   [1] {ECO:0000313|EMBL:KPV64674.1, ECO:0000313|Proteomes:UP000050312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BA1 {ECO:0000313|EMBL:KPV64674.1};
RX   PubMed=26494757; DOI=10.1126/science.aac7745;
RA   Evans P.N., Parks D.H., Chadwick G.L., Robbins S.J., Orphan V.J.,
RA   Golding S.D., Tyson G.W.;
RT   "Methane metabolism in the archaeal phylum Bathyarchaeota revealed by
RT   genome-centric metagenomics.";
RL   Science 350:434-438(2015).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + beta-nicotinamide D-ribonucleotide + H(+) =
CC         diphosphate + NAD(+); Xref=Rhea:RHEA:21360, ChEBI:CHEBI:14649,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:57540; EC=2.7.7.1; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00243};
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from
CC       nicotinamide D-ribonucleotide: step 1/1. {ECO:0000256|HAMAP-
CC       Rule:MF_00243}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00243}.
CC   -!- SIMILARITY: Belongs to the archaeal NMN adenylyltransferase
CC       family. {ECO:0000256|HAMAP-Rule:MF_00243}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KPV64674.1}.
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DR   EMBL; LIHJ01000033; KPV64674.1; -; Genomic_DNA.
DR   EnsemblBacteria; KPV64674; KPV64674; AOA65_0890.
DR   KEGG; barc:AOA65_0890; -.
DR   PATRIC; fig|1700835.3.peg.731; -.
DR   KO; K00952; -.
DR   UniPathway; UPA00253; UER00600.
DR   Proteomes; UP000050312; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000309; F:nicotinamide-nucleotide adenylyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.620; -; 1.
DR   HAMAP; MF_00243; NMN_adenylyltr; 1.
DR   InterPro; IPR004821; Cyt_trans-like.
DR   InterPro; IPR006418; NMN_Atrans_arc.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   Pfam; PF01467; CTP_transf_like; 1.
DR   TIGRFAMs; TIGR01527; arch_NMN_Atrans; 1.
DR   TIGRFAMs; TIGR00125; cyt_tran_rel; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00243};
KW   Complete proteome {ECO:0000313|Proteomes:UP000050312};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00243};
KW   NAD {ECO:0000256|HAMAP-Rule:MF_00243};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00243};
KW   Nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_00243,
KW   ECO:0000313|EMBL:KPV64674.1};
KW   Pyridine nucleotide biosynthesis {ECO:0000256|HAMAP-Rule:MF_00243};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00243,
KW   ECO:0000313|EMBL:KPV64674.1}.
FT   DOMAIN        6    137       CTP_transf_like. {ECO:0000259|Pfam:
FT                                PF01467}.
SQ   SEQUENCE   175 AA;  20204 MW;  DEB64909D9B3C99B CRC64;
     MVRRGVFVGR FQPLHNGHMG AIKDMLEKVD ELVIVVGSSQ YSHRMENPFT VGERITMIRE
     ALKEEGIPTS RCWIVPVPDV HIHMIWVAQV VGYTPKFDIV YTNEPLTRRL FIEAGFKVEP
     VPFHEREVYS ATEIRKRIMN GEDWEELVPK CVAQFIKEVG GVERLRDLAK TDKIT
//
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