ID A0A0Q0GBQ9_9GAMM Unreviewed; 383 AA.
AC A0A0Q0GBQ9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN Name=caiD {ECO:0000313|EMBL:KPZ53414.1};
GN ORFNames=AN393_02771 {ECO:0000313|EMBL:KPZ53414.1};
OS Pseudoalteromonas sp. P1-25.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Pseudoalteromonas.
OX NCBI_TaxID=1723758 {ECO:0000313|EMBL:KPZ53414.1, ECO:0000313|Proteomes:UP000050552};
RN [1] {ECO:0000313|EMBL:KPZ53414.1, ECO:0000313|Proteomes:UP000050552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1-25 {ECO:0000313|EMBL:KPZ53414.1,
RC ECO:0000313|Proteomes:UP000050552};
RA Jackson K.R., Lunt B.L., Fisher J.N.B., Gardner A.V., Bailey M.E.,
RA Deus L.M., Earl A.S., Gibby P.D., Hartmann K.A., Liu J.E., Manci A.M.,
RA Nielsen D.A., Solomon M.B., Breakwell D.P., Burnett S.H., Grose J.H.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPZ53414.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LKDW01000023; KPZ53414.1; -; Genomic_DNA.
DR RefSeq; WP_055018397.1; NZ_LKDW01000023.1.
DR AlphaFoldDB; A0A0Q0GBQ9; -.
DR PATRIC; fig|1723758.3.peg.2827; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000050552; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lyase {ECO:0000313|EMBL:KPZ53414.1}.
FT DOMAIN 27..364
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 383 AA; 41905 MW; 2DD18E2439E13DF2 CRC64;
MSNLTLLNNA DDPVLFETAI AENGSLIGLI TLNVPKALNA LNFDMIKLLE PQLRAWQDDD
AIAMVILKGA GDKAFCAGGD VVSLHHAMAQ GKPTSLVEEF FTLEYKLDYL IHTFDKPILV
WGNGIVMGGG LGLMAGASHR VVTETSRIAM PEQTIGLYPD VGGSYFLHKM PQGVGLFLGL
TSASINCEDA RFVSLADHFI DSTKYDAMLA QILAAKWGKT PSLNHERLTK LLTDLDNQSA
RMPKGYIKAN LATIQKLAEF NTLQEQVDYI LGLTIDDKWL QRAQKSLKHG CPLSCALVSE
QLKASKGQSL LTCFKMELGM SIRAGEVGEF QEGVRALLID KDGAPNWQYK SLSDVPQTII
DSFFANRFGE NHPLNGLHTP SHT
//
