ID A0A0Q0UX32_9SPHI Unreviewed; 777 AA.
AC A0A0Q0UX32;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Mechanosensitive ion channel protein {ECO:0000313|EMBL:KQB98883.1};
GN ORFNames=AQF98_21020 {ECO:0000313|EMBL:KQB98883.1};
OS Pedobacter sp. Hv1.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=1740090 {ECO:0000313|EMBL:KQB98883.1, ECO:0000313|Proteomes:UP000050543};
RN [1] {ECO:0000313|EMBL:KQB98883.1, ECO:0000313|Proteomes:UP000050543}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hv1 {ECO:0000313|EMBL:KQB98883.1,
RC ECO:0000313|Proteomes:UP000050543};
RA Ott B.M., Beka L., Graf J., Rio R.;
RT "Draft Genome Sequence of a Pedobacter sp. Strain Hv1, an Isolate From
RT Medicinal Leech Mucosal Castings.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQB98883.1}.
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DR EMBL; LLWP01000012; KQB98883.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0Q0UX32; -.
DR STRING; 1740090.AQF98_21020; -.
DR Proteomes; UP000050543; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050543};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 230..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..538
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 558..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..608
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 603..668
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 679..757
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 777 AA; 87586 MW; 7C7841CE7FB07DE4 CRC64;
MQEFAKRSAQ QSAADFKADK TQLVQEQVFV EIKKILQKAK LYLKTSIDTV QAQKELLSIQ
ADAEIAGDGV FNNTGTAHTY RNLTATSKIL SALLKRGQSQ KNSLDNHKQQ LSNLKYKLDS
LSSIKELFEF PTDSVQLSKY MQGLRVLAYE VTPIDSALTK AISSTQLLQN QTNLELFKLE
NSHDEANLYL KGISGQLSKK EFANIWESTG YFRPIDQIFK QAIAKGKLNL LYFVQSNVTI
IGCTLLLFII CFTYLRSLKK MYEERELLKD DLEGQLVLRY PFLSALVIIT NLSQFLFGSS
PFIFSLIFWV VSALSLSILF RGFITKYWMM VWLLLLSLFM LAALDNLILQ ATRLERWLMI
VLALMGVITG LIVFKTGKRN ELKEKLILYS IGLMFFLELI SLIANVFGSY NFAKALLVAG
YLNVVIAIMF LWTVRLINEG IKLAFSIYTK QDKKLFYVNF ERVGQDAPIL LYLLLVIGWF
ILFGRNFPEY SFLIEPLRGF FSDERTLGSY TFTINNLLLF VLILSISVLV SKVVSFFATD
QRTSSKQDHN TRKGLGSWIL LIRIAIIVLG LFLAFASAGI PMDKIAIVLG ALGVGIGFGL
QSLVNNLVSG LIIAFEKPVN LGDMVEIAGK DGTVKSIGFR SSIISTYDGA EIVMPNGDLL
NSHLVNWSTG AHKRRTAIVL QLTHDSDLEK IRDILLKLLA TDERVLSHPE PLVLFQDFKD
NRIEMKLFYW TKQLKDVAEV KSDLIVGINK VFAKHAIVLS LPQQDIYIHG ADGKKST
//
