ID A0A0Q0XX06_9FLAO Unreviewed; 317 AA.
AC A0A0Q0XX06;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=AAU57_04300 {ECO:0000313|EMBL:KQC34505.1};
OS Nonlabens sp. YIK11.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Nonlabens.
OX NCBI_TaxID=1453349 {ECO:0000313|EMBL:KQC34505.1, ECO:0000313|Proteomes:UP000051409};
RN [1] {ECO:0000313|EMBL:KQC34505.1, ECO:0000313|Proteomes:UP000051409}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIK11 {ECO:0000313|EMBL:KQC34505.1,
RC ECO:0000313|Proteomes:UP000051409};
RA Kwon Y.M., Kim S.-J.;
RT "Complete genome of flavobacterium.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQC34505.1}.
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DR EMBL; LBMJ01000001; KQC34505.1; -; Genomic_DNA.
DR RefSeq; WP_055413668.1; NZ_LBMJ01000001.1.
DR AlphaFoldDB; A0A0Q0XX06; -.
DR STRING; 1453349.AAU57_04300; -.
DR PATRIC; fig|1453349.3.peg.895; -.
DR Proteomes; UP000051409; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..317
FT /note="beta-lactamase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006186844"
FT DOMAIN 69..117
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
FT DOMAIN 119..274
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 317 AA; 35807 MW; 38BFFEA43BA2EA7B CRC64;
MLNRILIFLF LAASWNMSAA DDDAPLVNLA LNNKDVKTFQ NTTLQLNLKA QLMANPDWRK
LIQQKRMSVS LVDLNDAENI KYASINGSNM MYAASLPKIA VLYAAMDAIE NGELKDTPKV
RDDMWLMISK SNNAASTRMI DRVGFQKIED LMCDPSNPFY DKDGVGGLWV GKRYAAQGKR
NPEPIRGLSH AATTDAVAKF YYQLATGQLI NKTRSKEMLD IMENPSLHHK FVNTLDRIAP
DARLFRKSGS WKNWHSDSIL VWGEDGRKYI LVALIEDPNG EQIIRNLVQP AELALRKSVI
LPVELEQENE VVVRQDT
//
