ID A0A0Q2LR23_MYCGO Unreviewed; 255 AA.
AC A0A0Q2LR23;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Enoyl-CoA hydratase {ECO:0000313|EMBL:KQH78409.1};
GN ORFNames=AO501_03425 {ECO:0000313|EMBL:KQH78409.1};
OS Mycobacterium gordonae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1778 {ECO:0000313|EMBL:KQH78409.1, ECO:0000313|Proteomes:UP000051677};
RN [1] {ECO:0000313|EMBL:KQH78409.1, ECO:0000313|Proteomes:UP000051677}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CTRI 14-8773 {ECO:0000313|EMBL:KQH78409.1,
RC ECO:0000313|Proteomes:UP000051677};
RA Ustinova V., Smirnova T., Blagodatskikh K., Varlamov D., Larionova E.,
RA Chernousova L.;
RT "Mycobacterium gordonae draft genome assembly.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Could possibly oxidize fatty acids using specific components.
CC {ECO:0000256|ARBA:ARBA00002994}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O;
CC Xref=Rhea:RHEA:16105, ChEBI:CHEBI:15377, ChEBI:CHEBI:57318,
CC ChEBI:CHEBI:58856; EC=4.2.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00023709};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O;
CC Xref=Rhea:RHEA:20724, ChEBI:CHEBI:15377, ChEBI:CHEBI:58521,
CC ChEBI:CHEBI:137480; EC=4.2.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00023717};
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254, ECO:0000256|RuleBase:RU003707}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQH78409.1}.
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DR EMBL; LKTM01000223; KQH78409.1; -; Genomic_DNA.
DR RefSeq; WP_055578866.1; NZ_LKTM01000223.1.
DR AlphaFoldDB; A0A0Q2LR23; -.
DR STRING; 1778.A9W97_28730; -.
DR OrthoDB; 4284283at2; -.
DR Proteomes; UP000051677; Unassembled WGS sequence.
DR GO; GO:0004300; F:enoyl-CoA hydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR Gene3D; 1.10.287.2460; -; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR PANTHER; PTHR43802; ENOYL-COA HYDRATASE; 1.
DR PANTHER; PTHR43802:SF1; IP11341P-RELATED; 1.
DR Pfam; PF00378; ECH_1; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000051677}.
SQ SEQUENCE 255 AA; 26604 MW; 7C40AD5F59213787 CRC64;
MSDLVRVERD GPVTTVCINR PEARNAVNGP TAAALYTAFE RFDRDDTASV AVLCGEGGTF
CAGADLKAFG TPQANSVHRT GPGPMGPSRM MLSKPVIAAV DGYAVAGGLE LALWCDLRVA
EEDAVFGVFC RRWGVPLIDG GTVRLPRLIG HSRAMDMILT GRGVKADEAL AIGLANRVVP
KGQGRQAAQE LAAELAALPQ QCLRSDRLSA LHQWGLPESA AMDLEFASIS RVAAEALEGA
GRFAGGAGRH GAPAS
//
