ID A0A0Q3GK59_BRADI Unreviewed; 192 AA.
AC A0A0Q3GK59;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=DNA topoisomerase I DNA binding eukaryotic-type domain-containing protein {ECO:0000259|Pfam:PF02919};
GN ORFNames=BRADI_2g60537v3 {ECO:0000313|EMBL:KQK11496.1};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK11496.1};
RN [1] {ECO:0000313|EMBL:KQK11496.1, ECO:0000313|EnsemblPlants:KQK11496}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK11496.1,
RC ECO:0000313|EnsemblPlants:KQK11496};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK11496.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK11496.1};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK11496}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK11496};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
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DR EMBL; CM000881; KQK11496.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0Q3GK59; -.
DR STRING; 15368.A0A0Q3GK59; -.
DR EnsemblPlants; KQK11496; KQK11496; BRADI_2g60537v3.
DR Gramene; KQK11496; KQK11496; BRADI_2g60537v3.
DR InParanoid; A0A0Q3GK59; -.
DR Proteomes; UP000008810; Chromosome 2.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003917; F:DNA topoisomerase type I (single strand cut, ATP-independent) activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 2.170.11.10; DNA Topoisomerase I, domain 2; 1.
DR InterPro; IPR013030; DNA_topo_DNA_db_N_dom2.
DR InterPro; IPR008336; TopoI_DNA-bd_euk.
DR InterPro; IPR036202; TopoI_DNA-bd_euk_N_sf.
DR PANTHER; PTHR10290:SF23; DNA TOPOISOMERASE 1; 1.
DR PANTHER; PTHR10290; DNA TOPOISOMERASE I; 1.
DR Pfam; PF02919; Topoisom_I_N; 1.
DR SUPFAM; SSF56741; Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008810}.
FT DOMAIN 131..192
FT /note="DNA topoisomerase I DNA binding eukaryotic-type"
FT /evidence="ECO:0000259|Pfam:PF02919"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..115
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 192 AA; 21367 MW; 4EF87A919F50B5AE CRC64;
MNERHRRHNR CPGRVDYDLR RRSPSLMSGA PEEEDGRSRA RRPALCTAAA RDGPASGSSR
RKRGIRRCAA AFMPPSDQRP HASSVRRCAP LFSLANHGAS PPPPTEPPLP LPLAPVPISG
RGSRRWRSPP DPEKKALPEG KLKQEEKFMW AVVDGTREKV GTFRVEPPGL FRGRGEHPKM
GKLKQRILPS DI
//
