ID A0A0Q3JGS7_BRADI Unreviewed; 335 AA.
AC A0A0Q3JGS7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=poly(A)-specific ribonuclease {ECO:0000256|ARBA:ARBA00012161};
DE EC=3.1.13.4 {ECO:0000256|ARBA:ARBA00012161};
GN ORFNames=BRADI_1g32130v3 {ECO:0000313|EMBL:KQK17035.2};
OS Brachypodium distachyon (Purple false brome) (Trachynia distachya).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Stipodae; Brachypodieae; Brachypodium.
OX NCBI_TaxID=15368 {ECO:0000313|EMBL:KQK17035.2};
RN [1] {ECO:0000313|EMBL:KQK17035.2, ECO:0000313|EnsemblPlants:KQK17035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK17035.2,
RC ECO:0000313|EnsemblPlants:KQK17035};
RX PubMed=20148030; DOI=10.1038/nature08747;
RG International Brachypodium Initiative;
RT "Genome sequencing and analysis of the model grass Brachypodium
RT distachyon.";
RL Nature 463:763-768(2010).
RN [2] {ECO:0000313|EMBL:KQK17035.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bd21 {ECO:0000313|EMBL:KQK17035.2};
RG The International Brachypodium Initiative;
RA Lucas S., Harmon-Smith M., Lail K., Tice H., Grimwood J., Bruce D.,
RA Barry K., Shu S., Lindquist E., Wang M., Pitluck S., Vogel J.P.,
RA Garvin D.F., Mockler T.C., Schmutz J., Rokhsar D., Bevan M.W.;
RT "WGS assembly of Brachypodium distachyon.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:KQK17035}
RP IDENTIFICATION.
RC STRAIN=cv. Bd21 {ECO:0000313|EnsemblPlants:KQK17035};
RG EnsemblPlants;
RL Submitted (AUG-2018) to UniProtKB.
CC -!- FUNCTION: Ubiquitous transcription factor required for a diverse set of
CC processes. It is a component of the CCR4 complex involved in the
CC control of gene expression. {ECO:0000256|ARBA:ARBA00025148}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage of poly(A) to 5'-AMP.; EC=3.1.13.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001663};
CC -!- COFACTOR:
CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC Evidence={ECO:0000256|ARBA:ARBA00001968};
CC -!- SUBUNIT: Component of the CCR4-NOT complex, at least composed of CRR4
CC and CAF1 proteins. {ECO:0000256|ARBA:ARBA00011757}.
CC -!- SIMILARITY: Belongs to the CAF1 family.
CC {ECO:0000256|ARBA:ARBA00008372}.
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DR EMBL; CM000880; KQK17035.2; -; Genomic_DNA.
DR AlphaFoldDB; A0A0Q3JGS7; -.
DR STRING; 15368.A0A0Q3JGS7; -.
DR EnsemblPlants; KQK17035; KQK17035; BRADI_1g32130v3.
DR Gramene; KQK17035; KQK17035; BRADI_1g32130v3.
DR InParanoid; A0A0Q3JGS7; -.
DR Proteomes; UP000008810; Chromosome 1.
DR GO; GO:0030015; C:CCR4-NOT core complex; IBA:GO_Central.
DR GO; GO:0000932; C:P-body; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IBA:GO_Central.
DR GO; GO:0043928; P:exonucleolytic catabolism of deadenylated mRNA; IBA:GO_Central.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR039637; CNOT7/CNOT8/Pop2.
DR InterPro; IPR006941; RNase_CAF1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10797; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT; 1.
DR PANTHER; PTHR10797:SF37; POLY(A)-SPECIFIC RIBONUCLEASE; 1.
DR Pfam; PF04857; CAF1; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000008810};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
SQ SEQUENCE 335 AA; 36544 MW; B635E40DDE6FABDE CRC64;
MASSRPNDGG ERQLPVFSSR FFAPPPPRPA LSFQLPPQQR AVVPRRRHCH ADAAPSAVRI
MPVTAWNLDA AMELMASLLP LFPYVAVDTE YPGVVHHHSH SPNAAAAATA EERYAVAKAN
VDELPIVQLG ITLCDDQGRL PVFQDHLTGC HVEVSWEINF TDFDAGVHRH APESVNFLRS
QGVDFDLARA QGVTSNAFGH KFVSMLSSPS SNANKLTWAM FGGMYDLGYL FKILTGGQPL
PERKEMFVRE VKARLGGGRL FDAKYMAERC GRGDLRGVGL KRVAANLGVP RHYPEPPCLA
GPKSILACRI FTALRRSVFS PDGGACLEGC IDGMQ
//
