ID A0A0Q3LSW9_AMAAE Unreviewed; 832 AA.
AC A0A0Q3LSW9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Zinc fingers and homeoboxes protein 2 {ECO:0000313|EMBL:KQK73728.1};
GN ORFNames=AAES_164126 {ECO:0000313|EMBL:KQK73728.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK73728.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK73728.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK73728.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the ZHX family. {ECO:0000256|ARBA:ARBA00007440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK73728.1}.
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DR EMBL; LMAW01003151; KQK73728.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3LSW9; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 4.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 4.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR041057; ZHX_Znf_C2H2.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR15467:SF5; ZINC FINGERS AND HOMEOBOXES PROTEIN 2; 1.
DR PANTHER; PTHR15467; ZINC-FINGERS AND HOMEOBOXES RELATED; 1.
DR Pfam; PF00046; Homeodomain; 3.
DR Pfam; PF18387; zf_C2H2_ZHX; 1.
DR SMART; SM00389; HOX; 4.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 4.
DR PROSITE; PS50071; HOMEOBOX_2; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 107..135
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 282..321
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 445..495
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 535..579
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 634..684
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 284..322
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 447..496
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 537..580
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 636..685
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 704..747
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..782
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 832 AA; 92538 MW; F9748D0B3DC5BA09 CRC64;
MASKRKSTTP CMVRTSEVVE QEGTEGVEVP KEKENGAPQQ DSQKNWPSES SVKDCEVVEE
KPPAESQSKK PQGGYECKYC PYSTQNLNEF TEHVDTQHPN VILNPLYVCA ECNFTTKKYD
SLSDHNTKYH PGETNFKLKL IKRNNQTVLE QSIETTANDV TVTSSGLETA ECDDSLHGGI
SANKTPMMKL GKPKGETRKG PKKTEEGVTE NHVDGTLPRI ITEATEAIAC INGDLLHDVL
AHVMPSVQLP PNINLVPKVP VPLNSTKYNS ALDTNATMIN SFNKFPYPTQ AELSWLTAAS
KHPEEQIRIW FATQRLKHGI SWSPEEVEEA RKKMXNGTIQ AVPQTITVLP APLATAKMPQ
PIIQTALPCQ ILGQTGLVLT PVSNGSTVSC SPITLAVAPN QGQKRAIQTL SSAPEAKRPH
VVQVPEMPAK LTAVPLTPAS ERKKTKEQIA ELKASFMASQ FPDDTEVYRL IEATGLSRSE
IKKWFSDHRY RSQRGIMHIP GDALVKDQIA PSAGRHSRSF HPYTDFAPQR FKEKTQEQLR
ALEESFLRCS FPTQGELDRL RVETKLSRRE IDSWFSERRK IRDSMXQAVL DSMGSYRKIK
EQGAPNGAIS QAELLSSSQL PXALSGSSAT FKKTQEQSHL LKSTFARTQW PSPQEYDQLA
SQTGLTRTEI VRWFKENRSS LRTGSLKWID QYQKQYVVDG HNEQSQKKGS KHTESAKNGN
EVSRQHYQEH KKLNEENGGK PVVRAKRDCE PLKDSLLGNQ VEGMGRLECN SHDGHGSEEN
EEPAEVNWVE VTVGEDDAAS DCTDSWSQTA PEGQAELADF DSESISGENA HV
//
