ID A0A0Q3LYQ2_AMAAE Unreviewed; 3004 AA.
AC A0A0Q3LYQ2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Tetratricopeptide repeat protein 28 {ECO:0000313|EMBL:KQK75640.1};
GN ORFNames=AAES_142779 {ECO:0000313|EMBL:KQK75640.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK75640.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK75640.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK75640.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK75640.1}.
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DR EMBL; LMAW01002918; KQK75640.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3LYQ2; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR CDD; cd22666; FHA_CHK2; 1.
DR CDD; cd14084; STKc_Chk2; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 6.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR024983; CHAT_dom.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10098; RAPSYN-RELATED; 1.
DR PANTHER; PTHR10098:SF106; TETRATRICOPEPTIDE REPEAT PROTEIN 28; 1.
DR Pfam; PF12770; CHAT; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13424; TPR_12; 9.
DR Pfam; PF13176; TPR_7; 1.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SMART; SM00028; TPR; 25.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF48452; TPR-like; 7.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR PROSITE; PS50005; TPR; 11.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 90..152
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 197..462
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REPEAT 650..683
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 838..871
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 878..911
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 918..951
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1038..1071
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1118..1151
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1158..1191
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1401..1434
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1481..1514
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1521..1554
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1601..1634
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2532..2866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2887..2911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2939..3004
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1494..1521
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2555..2571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2605..2670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2698..2802
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2820..2856
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2943..2981
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3004 AA; 329931 MW; A70E5925A3D9A191 CRC64;
MSRESGSEAQ PPQGAPQSQS GASSSSGASQ GTSQSSSSSG TLSSXDTVPT QELPSIPEDQ
ESEELIPQPW GRLFALGKGF SNWDCVNDEY WFGRDKSCDY SFSKLGLSET GFYQNYSKKH
FRIFREMGPR SSYVAYIEDH SANGTFVNRE LIGKGKRLPL THNSEIALSV QTNKVFVFSD
PMVDDQLVFP REFREKYIMS KTLGSGACGE VKLAFEKSTC NKVAVKIINK RKFLASGIEA
NPAFNINTEI EILKKIDHPC LIKIKNFFEA EDYYIVLELM EGGELYDRLS RPVKMKEATC
KLYFYQMLLA VKYLHDNGII HRDLKPENVL LSSSEETCLI KITDFGQSKI LGETSLMKTL
CGTPTYLAPE VLNSLGTAGY SRAVDCWSLG VILFVCLCGY PPFNEQNTQL SLRDQITRGE
YTFISKEWKH VSHLALDLVK KLLVVDPSKR LTTEEALEHP WLQDEDMKST FQQLLAQTCG
SMNPPQASKM PIATRKRLYE NEEESGSSKR ALPSTSLQKM SLSVFSITCM VSTGMGRQCL
DAGCTSAVGR LRMRPAVPIS FFGSKSFGRK SPDSPMLSKA EFVEKVRQSN QACHDGDFHT
AIVLYNEALG ADPQNCILYS NRSAAYMKIQ QYDKALDDAI KARLLNPKWP KAYFRQGVAL
QYLGRHADAL AAFASGLAQD PKSLQLLVGM VEAAMKSPMR ESLEPTYQQL QKMKLDKSPF
VVVSVIGQEL LTAGHHGASV VVLEAALKIG TCSLKLRGSV FSALSSAYWS LGNTEKSTGY
MQQDLDVAKT LGDQTGECRA HGNLGSAFFS KGNYREALTN HRHQLVLAMK LKDREAASSA
LSSLGHVYTA IGDYPNALAS HKQCVLLAKQ SKDELSEARE LGNMGAVYIA MGDFENAVQC
HEEHLKIAKE LGNKREEARA YSNLGSAYHY RRNFDKAMSY HNYVLELAQE LAEKAIEMRA
YAGLGHAARC MQDLERAKQY HEEQLHIAES LQDQAAEGRA SSNLGIIHQM KGDYDTALRL
HKAHLSIAQE LSDYAAQGRA YGNMGNAYNA LGMYDQAVKY HRQELQISME VNDRASQAST
HGNLAVAYQA LGAHDRALQH YQNHLNIARE LRDIQSEARA LSNLGNFHCS RGEYVQAAPY
YEQYLRLSPE LQDMEGEGKV CHNLGYAHYC LGNYEEAVKY YEQDLALAKD LHDKLSQAKA
YCNLGLAFKA LMDFSKAEEC QKYLLSLAQS LNNSQAKFRA LGNLGDIFVC KKDVNGAIKF
YEQQLSLAHH VKDRRLEASA YAALGSAYRM VQKCDKALGY HTQELEVYQE LGDMLGECRA
HGHLAAVYMS LGKYTMAFKC YEEQLELGQK LKDPSIEAQV YGNMGITKMN MNVMEEAIGY
FEQQLAMLQQ LXGNESVLDR GRAYGNLGDC YEALGDFEEA IKYYEQYLSV AQSLNRMQDQ
AKAYRGLGNG HRAMGSLQQA LVCFEKRLVV AHELGEAFDK AQAYGELGSL HSQLGNYEQA
ISCLERQLNI AREMKDRALE SDAACGLGGV YQQMGEYDTA LQYHQLDLQI AEETNNPACQ
GRAYGNLGLT YESLGTYERA VVYQEQHLSI AAQMNDLVAK TVSYSSLGRT HHALQNYSQA
VMYLQEGLRL AEQLGRREDE AKIRHGLGLS LWASGNLEES QHQLYRASAL FETIRHEVQL
STDYKXSLFD LQTSSYQALQ RVLVSLGHHD EALAVAERGR TRAFADLLVE RQTGQQDSDP
YSPVTIDQVL ETVNGQRGLV LYYSLAAGYL YSWLLAPGAG ILKFHGCYLG DSLTEHAGDF
HEANSVTLQT VTNSALEQHI SSVREALGVE SYYTRACASS ETESEAGDIM DQQFEEMNNK
LNAMTDPTGF LRMVSRNNLL NRSCQSMSSL FSSTTSPVKD GTSSLPRRQT SFTKPPLRAL
YDLLIGPMEG GLMHSSGPVG RHRQLILVLE GELYLIPFAL LKGSSSNEYL YERFSLIAVP
SIQSLNPSSK SHARKNTSAY SSSTSMAAVI GNPKLPSAVM DRWLWGPMPS AEEEAYMVSE
LLSCQPLVGS AATKERVMSA LTQAECVHFA THVSWKLAAL VLTPNTDSTP VSSKNSFGNP
YTIPESLRMQ DDASDVESIS DCPPLQEFLL TAADVLDLRL PVKLVVLGSY QESNSKVTAD
GVIGLTRAFL AAGAQCVLVS LWPVPVAASK MFVHAFYSSL LNGMKASAAL GEAMKTVQGS
KQFSHPSNWA GFMLIGSDMK LNSPSSLVGQ ALTEILQHPD RARDALRVLL HLVEKSLQRI
QNGQHNSMYT SQQSVENKVG GIPGWQALLT AVGFRLDPPA SGLPAAVFFP TSDPGDRLQQ
CSTTIQSLLG LPNPALQALC KLITASETGE QLINRAVKNM VGMLHQVLVQ LQAGEKEQDF
SSAPIQVSIS VQLWRLPGCH EFLAALGFDL CEVGQEEVIL KTGKQANRRT VHFALQSLLA
LFDSTELPKR LSLDSSSSLE SLASAQSISN PIPQYQNPPF SPTCPDSIAS DAISVYSLSS
IASSMSFVSK PESMADGVGQ RGRQDYEKPK NIYPHRSAGQ SQLSPQSSTV VSKDEEEYEG
FSIISNEPLA SYQENIKPRF SPDHKQSKTG QTGGIKESVN SKGSISTPNS PVKMTLIPSP
NSPFQKVGKL ASSDTGESDQ SSTETDSTVK SQEDSNPKLD PQELAQKILE ETQSHLIAVE
RLQRSSSQIS KSNNSDDGAP SPAGASAFRS SETSAFSRPI SSSQKNQSSP LAMKPKPPTR
SSSLQKVSSG YNSPTTSEMS NKEGTGQYSG QPSPSCDSHA SLTEQPHFKL KYPXSPYSAH
ISKSPRNISP SSGHQSPGGS TPSPALSYSS AGSARSSPAD APDIDKLKMA AIDEKVQAIH
NLKMFWQSSP HHSPGPVKIL RGAPGTMTSK KDVLSLLNLS PRHSKEESVD KLELKDLSIE
QHLAASPQKN PPNGHXRSET ASAVTPTHSP APSSAPGTTR PVRLPSGNGY KFLSPGRFFP
SSKC
//
