ID   A0A0Q3M3K2_AMAAE        Unreviewed;      1086 AA.
AC   A0A0Q3M3K2;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   22-FEB-2023, entry version 22.
DE   RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
GN   ORFNames=AAES_127236 {ECO:0000313|EMBL:KQK77263.1};
OS   Amazona aestiva (Blue-fronted Amazon parrot).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX   NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK77263.1, ECO:0000313|Proteomes:UP000051836};
RN   [1] {ECO:0000313|EMBL:KQK77263.1, ECO:0000313|Proteomes:UP000051836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FVVF132 {ECO:0000313|EMBL:KQK77263.1};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ferlin family.
CC       {ECO:0000256|ARBA:ARBA00007561}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQK77263.1}.
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DR   EMBL; LMAW01002769; KQK77263.1; -; Genomic_DNA.
DR   STRING; 12930.A0A0Q3M3K2; -.
DR   Proteomes; UP000051836; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd04017; C2D_Ferlin; 1.
DR   CDD; cd04037; C2E_Ferlin; 1.
DR   CDD; cd08374; C2F_Ferlin; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 4.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR037723; C2D_Ferlin.
DR   InterPro; IPR037724; C2E_Ferlin.
DR   InterPro; IPR037725; C2F_Ferlin.
DR   InterPro; IPR012968; FerIin_dom.
DR   InterPro; IPR037721; Ferlin.
DR   InterPro; IPR012560; Ferlin_A-domain.
DR   InterPro; IPR012561; Ferlin_B-domain.
DR   InterPro; IPR006614; Peroxin/Ferlin.
DR   PANTHER; PTHR12546:SF44; DYSFERLIN; 1.
DR   PANTHER; PTHR12546; FER-1-LIKE; 1.
DR   Pfam; PF00168; C2; 3.
DR   Pfam; PF08165; FerA; 1.
DR   Pfam; PF08150; FerB; 1.
DR   Pfam; PF08151; FerI; 1.
DR   SMART; SM00239; C2; 3.
DR   SMART; SM00694; DysFC; 1.
DR   SMART; SM00693; DysFN; 2.
DR   SMART; SM01200; FerA; 1.
DR   SMART; SM01201; FerB; 1.
DR   SMART; SM01202; FerI; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 4.
DR   PROSITE; PS50004; C2; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051836}.
FT   DOMAIN          79..215
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          669..794
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   REGION          1061..1086
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1086 AA;  124037 MW;  1376EDC538E7CED7 CRC64;
     MLRCLLQRAT HLPNLEKGDK QSDPVASLTF RGHAFLRKWL LLSDPEDFSA GAKGYLKVSV
     FVLGPGDEAP LEKKEVSEDK EDIEGNLLRP TGVTLRGAHF CLKIFKAEDL PQMDDAVMDN
     VRQIFGFESN KKNLVDPFVE VSFAGKTLYS RILEKNANPQ WNQCLTLPAM FPSMCEKMRI
     RVTDWDRLTH NDVIGTAHLC MSKISAPGGE LEDEFPALSK PLKASDRTSP LASGFAVELG
     NGFGSGAPGA LDGKYLRRRK YSLFAAFYSA TMLQDVDDAI QFEVSIGNYG NKFDTTCLPL
     ASSTQYSRAV FDGCQYYYLP WGNVKPVVVL SSYWEDISYR TDAQNLLHHA ADRLEANLEK
     VHLALKANRS PSELDALCAQ LLDDTIADCS LTLPDVLAKP ASTHLDQNLN ISNCCGKNCG
     KLQTIFLKYP QEEVMGPKIP AQIRVQLWFG LSVDEKEFNQ FAEGKLSVFA ETYENQTKLA
     LVGNWGTTGL TYPKYSDVTG KIKLPKDSFR PSTGWTWAGD WFICPEKTLL HDVDAGHLSF
     VEEVFENQLR LPGGQWIHMT DAYTDVNGEK VLHKDEIECP PGWKWEDVEW DTDLNRAVDE
     KGWEYGITIP PDRKPKAWVP AEKMYHTNRR RRWVRLRRRD LAQMETMRKG GVTDDKSDDG
     KSISTLSFGV NRPTISCIFD CGNRYHLRCY MYQARDLIAM DKDSFSDPYA IVSFLHQSQK
     TVVIKNTLNP TWDQTLIFYE IEIFGDPQNV AESPPNIVVE LYDQDTYPAL HHIPGFENEL
     SSTLDECDPY VKISVGKKSI NDQDNYLPCT LEPVFGKMFE LSCTLPLEKD LKITLYDYDL
     LSKDEKIGET IIDLENRSGP NQWRDQLRPS QLLHLFSLQH NYKAPTYKSD RVIFREQEYV
     LSELEDGKAP NPHLGPVEER LALYVLRKQG LVPEHVETRP LYSPLQPEIE QLFMQRVWLC
     SWLVGHEENK QKTDVHYRSM GGEGNFNWRF VFPFDYLPAE QMCYIAKKEH FWSLDKTENK
     IPPQLIFQIW DNDKFSFDDY LVXGKCSMQG KLEMTLEIVA EQEHEERPAG MGRDEPNMNP
     KLEDPK
//