ID A0A0Q3M9U3_AMAAE Unreviewed; 567 AA.
AC A0A0Q3M9U3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=E3 ubiquitin/ISG15 ligase TRIM25 {ECO:0000313|EMBL:KQK79461.1};
GN ORFNames=AAES_103906 {ECO:0000313|EMBL:KQK79461.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK79461.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK79461.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK79461.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK79461.1}.
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DR EMBL; LMAW01002589; KQK79461.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0Q3M9U3; -.
DR STRING; 12930.A0A0Q3M9U3; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19842; Bbox1_TRIM25-like_C-IV; 1.
DR CDD; cd19776; Bbox2_TRIM25_C-IV; 1.
DR CDD; cd16597; RING-HC_TRIM25_C-IV; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF40; E3 UBIQUITIN_ISG15 LIGASE TRIM25; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Ligase {ECO:0000313|EMBL:KQK79461.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 15..56
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 371..565
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 567 AA; 63875 MW; 2E3CA2E2747BB159 CRC64;
MAEPGLSALE EELTCSICLC LFSSPVTVPC GHNFCASCLQ LSWAGVSKNF SCPQCRATFM
DRPQLQKNTV LCRVVQQLQG GTGAEEEKEK EEEEEETGPV LCDTCLQAPA VRTCLTCTAS
FCEEHLQPHQ ESRAFRDHQL CPPLRDLQQR KCPQHNKLFE FFCSHHGSCI CSLCLLGHKL
CNTTPLELAK ANAEVSGGGS QLLLGWSSPL VPESLVALKK RLTELHNQNE KAAWAMNTVR
MNQGQAAEKI SRKKDLILSE FSEIKALIEE REIQILKAIA DEENRVSNKF ESIYGILGSK
KNEIQSLSDQ IDMALTEVDD LLFLKRATAL QRTSIKDAFV PVVEIDQNMI DSSYQSAINL
KDTVKLSMTL PEEKNVEEEK KKSAKVDAAN VTLDYNTAHN KVILSDRHTK MSVSDTPMKY
NQLPQRFTDC YQVLGFQSFK RGVHYWEVEM QQNNFCGIGI CYGSMERHGP ESRLGRNSRS
WCIEWFNNKI SSWHNDVEKC LPNTKATRIG VLLHCEAGFV IFLAVGEKHN LIYKYKTEFT
EAVYPAFWLF SSGTVLTLCQ LKNSSLN
//
