ID A0A0Q3MPA6_AMAAE Unreviewed; 428 AA.
AC A0A0Q3MPA6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 08-NOV-2023, entry version 27.
DE SubName: Full=Bone morphogenetic protein 2-like protein {ECO:0000313|EMBL:KQK84343.1};
GN ORFNames=AAES_53087 {ECO:0000313|EMBL:KQK84343.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK84343.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK84343.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK84343.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK84343.1}.
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DR EMBL; LMAW01001114; KQK84343.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3MPA6; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR PANTHER; PTHR11848:SF277; TGF_BETA_2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..428
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006205914"
FT DOMAIN 242..361
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 428 AA; 48315 MW; 05868521D57C7FC6 CRC64;
MAGLELALAL ALALAGLLGL PAARGLPLRP GPRDDVLAAA LQRLQEVFDI EELPPDVLPR
KKPPQFMIDL FNKVADANGI TRGPGLLESD VVRSFEDXVH VDQYHFYFDI SAMEKGEQML
KAEFRVFKLK RTHVSMRSDV KHFCKVSKWV GNSSSNHGFL ITATHIXNNR IEHNLVRFAK
SHGTLQESRN ALLVLFTNSN KRRSPSSIPS ATKLEMKPAK NDASHVSXET QVIESRNAGM
NRRPRAAEIP STKSQVTVCH RRELYVDFHA IGWSGWIIYP XGYNAFYCEG SCLFPLGESL
NATNHATVQS IVHTLKLSQD ISTPCCVPGE LKSLNLLYFD DKENVVLKNY KDMVATRKWD
IYVFYLKDPW KIHSPGGLLP EKRGEXLSAY HEFQDFPTDT KPSRLPPDLL RSHMQIYTGS
KRNMFRDS
//
