ID A0A0Q3P5G5_AMAAE Unreviewed; 450 AA.
AC A0A0Q3P5G5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Serine/threonine-protein kinase TOR {ECO:0000256|RuleBase:RU364109};
DE EC=2.7.11.1 {ECO:0000256|RuleBase:RU364109};
GN ORFNames=AAES_256155 {ECO:0000313|EMBL:KQK75907.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK75907.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK75907.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK75907.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|RuleBase:RU364109};
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family.
CC {ECO:0000256|RuleBase:RU364109}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK75907.1}.
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DR EMBL; LMAW01002900; KQK75907.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3P5G5; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024585; mTOR_dom.
DR PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR PANTHER; PTHR11139:SF9; SERINE_THREONINE-PROTEIN KINASE MTOR; 1.
DR Pfam; PF11865; DUF3385; 1.
DR SMART; SM01346; DUF3385; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU364109};
KW Kinase {ECO:0000256|RuleBase:RU364109};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU364109};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Serine/threonine-protein kinase {ECO:0000256|RuleBase:RU364109};
KW Transferase {ECO:0000256|RuleBase:RU364109}.
FT DOMAIN 99..269
FT /note="Serine/threonine-protein kinase mTOR"
FT /evidence="ECO:0000259|SMART:SM01346"
SQ SEQUENCE 450 AA; 50980 MW; 3FD2220DC672A567 CRC64;
MLGHLVSNAP RLIRPYMEPI LKALIVKLKD PDPDPNPGVI NNVLATIGEL AQVSGLEMRK
WVDELFIIIM DMLQDSSLLA KRQVALWTLG QLVASTGYVV EPYRKYPTLL EVLLNFLKTE
QNQGTRREAI RVLGLLGALD PYKHKVNIGM IDQSRDASAV SLSESKSSQD SSDYSTSEML
VNMGNLPLDE FYPAVSMVAL MRIFRDQSLS QHHTMVVQAI TFIFKSLGLK CVQFLPQVMP
TFLNVIRVCD GAIREFLFQQ LGMLVSFVRS HIRPYMDEIV TLMRDFWVMN NSIQSTIILL
IEQIVVALGG EFKLYLPQLI PHMLRVFMHD NSQSRIVSVK LXNAXQLFGA NLDDYLHLLL
PPIVKLFDAP DVPMVARKAA LETVDRLTES LDFTDYASRI IHPIVRTLDQ SPELRTTAMD
TLSSLVFQLG KKVXLFLDLK AHKRRDCHKD
//
