ID A0A0Q3PJ58_AMAAE Unreviewed; 876 AA.
AC A0A0Q3PJ58;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN ORFNames=AAES_139853 {ECO:0000313|EMBL:KQK76276.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK76276.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK76276.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK76276.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the beta type-B retroviral polymerase family.
CC HERV class-II K(HML-2) pol subfamily. {ECO:0000256|ARBA:ARBA00010879}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK76276.1}.
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DR EMBL; LMAW01002867; KQK76276.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3PJ58; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR013057; AA_transpt_TM.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR33064:SF29; LRRGT00076; 1.
DR PANTHER; PTHR33064; POL PROTEIN; 1.
DR Pfam; PF01490; Aa_trans; 2.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 434..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 513..533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 632..653
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 673..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 707..728
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..777
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 789..814
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 820..843
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 855..875
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..133
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 876 AA; 98724 MW; 5E0A51764BA5CD9D CRC64;
MLELQYELES KVAKWDATTD IANAFCSIPL AAECRPQFAF SWRGIQYTWN RLPQGWKHSP
TICHGLIQTA LEQGQAPEHL QYIDDIIVCG DTAEGVFEKG RKTLQILLKA SFDIKQSKVK
GSAQEIQFWG IKQQDRCCQI PTDVINKITA MSPPTNKKGT QAFLDVVGFW RMHIPNYSLI
VSPLYHETRK NNDFKWGPEQ QQAFEQIKRE IAHAVALGPV RTGPDVKHVL YTAAMENGPT
WSLWQKAPRE TRGRPLGSWS RGYRGSEASY TPTEKEILAA YEGARAASES EQHSEFLLTQ
KTSESRQNLE EGGTFTNMEE DTKPLLVPVG GDESNYGIMN IQFNPEDFKC KRPFHVEPTN
IVSVNDDMQR VTDEASAMNK RIHYYSRLTS PADRALIAPD HVLPAPDEIY VYSPLGTAFK
VDSCTDGYGK NSSIVTIFMI WNTMMGTSIL SIPWGIKQAG FTSGIILILL MGILTLYCCY
RVVKSRKMIP LLDTSNWEFP DVCKYYFGSF GQWSSLLFSM VSLVGAMVVY WVLMSNFLFN
TGKFIYNFVH DVNVTDIVPG TNGSNKVICP SAASSHPPQN RSVMFSSGND TGFELFEKWW
NKSQTVPFYL VAILLPLLNL KSPSFFAKFN VLGTVSVVYL VLLVTVKAAR LGIHLEYNWF
TENDFFVPEF RIQFPQLTGV LTLAFFIHNC VITLLQNNRN QENNVRDLSI AYFLVGLTYL
YVGVIIFASF PSPPLSKECI EQNFLDNFPS DDIMSFVARI FLLFQMMTVY PLLGYLARVQ
LLRQFFGNAY PSIFHVLILN IAIVGAGVAM AIFYPNIGGI IRYSGATCGL AFVFVYPSLI
YLISQHRAGR LTGPALIIHI FIILLGLANL IXQFLL
//
