ID A0A0Q3QVZ6_AMAAE Unreviewed; 411 AA.
AC A0A0Q3QVZ6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE RecName: Full=Protrudin {ECO:0000256|ARBA:ARBA00015523};
DE AltName: Full=Zinc finger FYVE domain-containing protein 27 {ECO:0000256|ARBA:ARBA00032025};
GN ORFNames=AAES_128998 {ECO:0000313|EMBL:KQK77297.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK77297.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK77297.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK77297.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, growth cone membrane
CC {ECO:0000256|ARBA:ARBA00004460}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004460}. Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004337}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004337}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Recycling endosome membrane
CC {ECO:0000256|ARBA:ARBA00004195}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004195}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK77297.1}.
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DR EMBL; LMAW01002767; KQK77297.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3QVZ6; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032584; C:growth cone membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0071787; P:endoplasmic reticulum tubular network formation; IEA:InterPro.
DR GO; GO:0072659; P:protein localization to plasma membrane; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd15723; FYVE_protrudin; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR042405; Protrudin.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR14543; PROTRUDIN; 1.
DR PANTHER; PTHR14543:SF1; PROTRUDIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT TRANSMEM 93..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 344..410
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 411 AA; 45205 MW; D9EDE32F8431D27D CRC64;
MQAVERDGAA GSPEGAAAAG DAPPELPSPP PKAAAAAFDL LELVRSYRRL ELYLEPLRDA
AEGVRSLLRW QRPMCSLLVC LGLNFLLLTL GKAAWYSVLA LLVVVPALLG YVQETCRAQP
SEPELVRRRY HSVRREDLRK VQLSKQEAIA QVKSFLIQLE GFLSGMCCXC EAVYRVLYWE
NPTVSSQFYG ALLGTVCVLY LLPLCWVLAI LNSTLFLGNT QFYQVILELR ASIEQCVGAK
PLESTPEPAE PLPAAVPLDQ TPTPTSTEDL TPGSVEEAEE AEPDEEFKDA IEENQLLVME
DDESSQCSAD FDLSLPDNGF MSKNEVIRSK VSRLTERLRK RYPSNNFGSC TGCGATFSVL
KKRRSCSNCG NSFCSRCCSF KVPKAVMGAT APEAQRETVF VCALCNQVLI K
//
