ID   A0A0Q3RBE4_AMAAE        Unreviewed;       819 AA.
AC   A0A0Q3RBE4;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Enhancer of filamentation 1 {ECO:0000313|EMBL:KQK82729.1};
GN   ORFNames=AAES_67418 {ECO:0000313|EMBL:KQK82729.1};
OS   Amazona aestiva (Blue-fronted Amazon parrot).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX   NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK82729.1, ECO:0000313|Proteomes:UP000051836};
RN   [1] {ECO:0000313|EMBL:KQK82729.1, ECO:0000313|Proteomes:UP000051836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FVVF132 {ECO:0000313|EMBL:KQK82729.1};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC       {ECO:0000256|ARBA:ARBA00004246}.
CC   -!- SIMILARITY: Belongs to the CAS family. {ECO:0000256|ARBA:ARBA00007848}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQK82729.1}.
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DR   EMBL; LMAW01001747; KQK82729.1; -; Genomic_DNA.
DR   STRING; 12930.A0A0Q3RBE4; -.
DR   Proteomes; UP000051836; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   CDD; cd11550; Serine_rich_NEDD9; 1.
DR   CDD; cd12002; SH3_NEDD9; 1.
DR   Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 1.
DR   Gene3D; 1.20.120.830; Serine-rich domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR021901; CAS_C.
DR   InterPro; IPR037362; CAS_fam.
DR   InterPro; IPR035746; NEDD9_SH3.
DR   InterPro; IPR014928; Serine_rich_dom.
DR   InterPro; IPR038319; Serine_rich_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR10654; CAS SCAFFOLDING PROTEIN; 1.
DR   PANTHER; PTHR10654:SF20; ENHANCER OF FILAMENTATION 1; 1.
DR   Pfam; PF12026; CAS_C; 1.
DR   Pfam; PF08824; Serine_rich; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          1..59
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          241..261
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          351..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          572..608
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        586..605
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   819 AA;  91440 MW;  7D24E288D8BD09D6 CRC64;
     MARALYDNVP ECAEELAFRK GDILTVIEQN TEGLEGWWLC SLHGRQGIVP GNRVKLLIGP
     VVQDSPPGQD MSSSGHMIRQ SFNXQKIYXV PSSHASARDP VYQVPPSHQG XYQIPTGHGL
     AGQDIYQVPP SMQRCIDSPA LTNKVITPVR SGQGYVXEFP PKYQKDTYDI PPVRPLQGIY
     DIPPTSVKGP ALPVPMGEAK AFGVYXIPPA KAVXATHPSA CRDDTGLREN VQDFSSAVGH
     SARPEGVYDX PPPITKATGK ELNKFPPESF LLSDGVPQKH GVYDIPMNHQ NHFLGQQIAP
     QKDVYDTPRG VAFPGQQTGL NERLIPEGRE GVYDVPPPVL QDTKGLQDVT DGINRLSFSS
     TGSTRSNMST SSTTSKDSSF SASTAQDKRL ILDPDTAIER LYRLQQMVET AVNNLMAFVT
     ADWRSYGYME KHINEIHTAV DKVEQSLLEY LQFAKGSAAN ASCLSEFSLL NKMRREVQRL
     EDSHQILTQT SHDLNSYNWS LNVLAVNRLQ NKCDDLDRFV MVARTVPDDA KELTTTISVN
     AEMLFKQALS SSRFKNVPES ITNIPDYVYD NPHMQRHGEK AQNHCTSLPP LLSKGQHPHN
     TTSESSEKSW MDDXDYVHLQ GKEEFERQQK ELLEKENIMK QSKMELEHHQ ISQFQRLEQE
     ITKPVENDIS KWKPPQALQT ANSAATSRDS QLLLFYSDQC ETHFNSLLNA IDAFFSCVNA
     SQPPRIXVAH SKFVILSAHK LVFXGDMLTR QVTTQDIRNK VMNSSNLLCE LLRSVVLATK
     TAALHYPNTA ALQKMVDQVT ELSRHAQLFK LSLVQMASL
//