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Database: UniProt
Entry: A0A0Q3T152_AMAAE
LinkDB: A0A0Q3T152_AMAAE
Original site: A0A0Q3T152_AMAAE 
ID   A0A0Q3T152_AMAAE        Unreviewed;      1384 AA.
AC   A0A0Q3T152;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   05-JUN-2019, entry version 20.
DE   SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 {ECO:0000313|EMBL:KQK74262.1};
GN   ORFNames=AAES_159358 {ECO:0000313|EMBL:KQK74262.1};
OS   Amazona aestiva (Blue-fronted Amazon parrot).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX   NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK74262.1, ECO:0000313|Proteomes:UP000051836};
RN   [1] {ECO:0000313|EMBL:KQK74262.1, ECO:0000313|Proteomes:UP000051836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FVVF132 {ECO:0000313|EMBL:KQK74262.1};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KQK74262.1}.
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DR   EMBL; LMAW01003067; KQK74262.1; -; Genomic_DNA.
DR   Proteomes; UP000051836; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd04385; RhoGAP_ARAP; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   Gene3D; 1.10.555.10; -; 1.
DR   Gene3D; 2.30.29.30; -; 4.
DR   Gene3D; 3.30.40.160; -; 1.
DR   InterPro; IPR037278; ARFGAP/RecO.
DR   InterPro; IPR001164; ArfGAP_dom.
DR   InterPro; IPR038508; ArfGAP_dom_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR037858; RhoGAP_ARAP.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   Pfam; PF01412; ArfGap; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00788; RA; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   Pfam; PF07647; SAM_2; 1.
DR   SMART; SM00105; ArfGap; 1.
DR   SMART; SM00233; PH; 5.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   SUPFAM; SSF48350; SSF48350; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   SUPFAM; SSF57863; SSF57863; 1.
DR   PROSITE; PS50115; ARFGAP; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 3.
DR   PROSITE; PS50200; RA; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000051836};
KW   GTPase activation {ECO:0000256|SAAS:SAAS01175775};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT   DOMAIN       19     49       SAM. {ECO:0000259|PROSITE:PS50105}.
FT   DOMAIN      147    239       PH. {ECO:0000259|PROSITE:PS50003}.
FT   DOMAIN      255    344       PH. {ECO:0000259|PROSITE:PS50003}.
FT   DOMAIN      341    482       Arf-GAP. {ECO:0000259|PROSITE:PS50115}.
FT   DOMAIN      643    741       PH. {ECO:0000259|PROSITE:PS50003}.
FT   DOMAIN      750    926       Rho-GAP. {ECO:0000259|PROSITE:PS50238}.
FT   DOMAIN      955   1048       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   REGION     1197   1221       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A0Q3T152}.
FT   REGION     1244   1384       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A0Q3T152}.
FT   COILED      325    345       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS   1203   1218       Polyampholyte. {ECO:0000256|MobiDB-lite:
FT                                A0A0Q3T152}.
FT   COMPBIAS   1330   1344       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0Q3T152}.
SQ   SEQUENCE   1384 AA;  156422 MW;  1E2E54A5E5566063 CRC64;
     MSSPCGPDSD IADWLATIHL ESDRLQQLGI TATGHRKRIL NLVQQTRGAG ISSDQSYEAV
     SELDLEREAC RTSSECSSEG RNEDEEARSR LIDRIIQNDT EGYSTVEAPQ ADGTPFILPA
     HLYPDEVLDD LTISPYASFT SLSEPRPTML SGWLDKLSPQ GNYVFQRRYV RFDGKNLMYF
     SSEKEPYPKG VIPLSVIEMA RCTKDNKFQV ITSHRIFVFR AENEAQRNEW CSTLQKKVTE
     QRLVGSRPRP ANTAHCQKSG TLELKGQKSK VFATLSLPEM WLYKSEQFFK MGIGICVIEM
     RGSTIREAKN RSXELITPSK IFSFVAESER EKREWMEALQ EAIAEMLYDY EVAEKIWSNK
     ANKHCADCWA PSPDWASINL CVVICKQCAG QYISHGVPWV WVRGAAWGQH RSLGSNISKV
     QSLKLDTSVW SNEIVQLFIM LGNDRANRFW AARLPATEAL HPDASAEQRR DFISCKYREG
     RYRLPHPHYT TQEDVLQEPG LEGVYNEITQ PVAHSGYLYR ATAPHKLPGT KKSKEDFQRT
     WCSLERALLF FETEKCTEPL GHIEXGDLLS MGVSRAQAVT SPGPTERFRF TLELFLTGEK
     VQQLGTDGPE TLQAWASAIG KLTSRSILQW FTPVSCHCLL GYEFQRVGQL RYKCMLNPER
     WQQAFFILQK AHLFICPAED DGAEDSINLR RLQELSLVPP TETPEKKELL ILVEMGRTFY
     LQGLSRADSA AWYSDIQASA GGRGNALRDQ QLSRADIPII VDSCIAFITQ YGLRHEGIYR
     KNGAKSRIKV LMEEFRRDAR NVKLRISDNF IEDVTXVLKR FFRELEDPVF TLELHPQWKE
     AAEIPSKPQR LERYKELIQR LPRLNHKTLA ALIGXLYRVQ KCADLNQMST KNLSLLFAPS
     LFQTDGKGEH EVKVMEDLID NYVSIFNIDE DQVSQMDLEN SLITTWKDTQ LSQAGDLIIE
     VYLEQKLPDC CVTLKVSPTM TAEELTNHVL EMRNVAASLD IWLTFEALEN GELERPLHPK
     EKVLEQALQW CKLPEPSAAY LLVKKVPIGE GSCLFTGVKR ETPKCGLLKC REEPPKLLGN
     KFQERYFVIR DRRLLLLKEK RSAKPEREWP LDAAKVYMGI RKKLKPPAQY LVCSGQAELW
     DWTTSILKAQ HDDLRPVVLR RHSSSDLAKQ KFGTMPLVPL HGDSTDATML SANQTLPMKV
     HQDSLEEQQE KEADADPVYE EVGNFPELAT LELGQGLLAD LSAVPPMDRS KKPSLFSEHP
     PATALRSSLP ASPAQRMAGP SVTKALSLER GLNLESDKAP AQGLRPTKTA SLERNVESSL
     ALGRDWEQAA TPGSSPSADT TMEMPRKRSI QPPSPISDKL IQELSSVILR KNEGQPPGPG
     QPVT
//
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