ID A0A0Q3TVK2_AMAAE Unreviewed; 1059 AA.
AC A0A0Q3TVK2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Integrin alpha-11 {ECO:0000313|EMBL:KQK84758.1};
GN ORFNames=AAES_45888 {ECO:0000313|EMBL:KQK84758.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK84758.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK84758.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK84758.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK84758.1}.
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DR EMBL; LMAW01000980; KQK84758.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3TVK2; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0009986; C:cell surface; IEA:UniProt.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR048286; Integrin_alpha_Ig-like_3.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF21; INTEGRIN ALPHA-11; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR Pfam; PF20806; Integrin_A_Ig_3; 1.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 5.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 3.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51470; FG_GAP; 5.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003762};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU003762};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU003762}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT CHAIN 23..1059
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT /id="PRO_5005965347"
FT TRANSMEM 1013..1037
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 27..85
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 99..189
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REPEAT 199..250
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 310..371
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 372..430
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 461..521
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
SQ SEQUENCE 1059 AA; 118383 MW; C2C569EFB9C0AF76 CRC64;
MDLPSGMLLA CSLCLLPGFT DTFNIDTKRP KIIAGSKEAY FGYTVQQHDI GGKKWLVVGA
PYETNGXQKT GDVYKCLVTS DTHNNCTKLN LGTASEAFQK GGRKGAKRVM IVITDGESHD
SPDLEKVIED SEKDNVTRYA VAVLGYYNRR GINPEAFLNE IKFIASDPDD KHFFNVTXEA
ALKDIVDALG ERIFSLEGTN KNEISFGLEM SQTGFSSHVV EDGILLGAVG AYDWNGAVLK
ETSSGKVIPL RESYLQEFPE ELKNHGAYLG YTVSSVISTR HERIYVAGAP RFNHTGKVIL
FSMHNNRNLT IHQALKGEQI GSYYGXEINS LDVNGDGITD VLLVGAPMYF SEGRERGKVY
VYTLRENRFI PSGALLDLQS YQNSRFGSCI AAVPDLNQDS YNDLVVGAPL EDEHQGAIYI
FLGFKETILK KGLEEAGMAN PSFTGRDAPQ ETRLDSPFSF QRIAAADLAP GLMYFGCSIH
GQLDLNEDGL VDLAVGSLGN AVLLWSRSVV QVNASIRFEP PKINIFTKDC KRNGKDATCM
SAFICFTAVF LSAXFQTSSV ALRYNTTIDE RRYTPRAHLD DSGERHTQKE LVLLAGQEHC
DRLHFHVLDT ADYVKPVTFS IDYELEHLEN GPMLDDGWPT SLRVLVPFWN GCNEDEHCVP
DLVLDAKSDV PSAMEYCRRA LRRAPPDCSA FTLSFDTSVF XIESSRRRVA VEAVLENRGE
NAYSTVLNIS FSRNLQFASL IPKDDTDINI DCMTEDKNPN KKMCNVSYPF FRAKAKVAFR
LDFEFSKSIF LQTLEIYLVA NSDSEEKEST KEDNFAHLNF HLKYEADLLF TRASSLDYYE
IRSNSSLERY DSIGPPFHCT FKLQNLGFFP VEGVTIKLTI PVATRAGNRL LLLTEFLVDQ
ENTTCNTWGN TTDYRRTPGX EDLSRTPHLN HSNSDVVSID CNVKLAPNEE LSLHLRGNLW
MKSLKALKFK SLKLTMSAAL QRHFGSPFIF REEDPSRQIT FEISKPEESQ IPIWIILGST
LGGLLLLALL VLALWKLGFF KSGSRRRAAE XERSTQGLE
//
