ID   A0A0Q3U3L9_AMAAE        Unreviewed;       705 AA.
AC   A0A0Q3U3L9;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Protein Smaug homolog 1 {ECO:0000256|ARBA:ARBA00041183};
DE   AltName: Full=Sterile alpha motif domain-containing protein 4A {ECO:0000256|ARBA:ARBA00041298};
GN   ORFNames=AAES_07759 {ECO:0000313|EMBL:KQL60504.1};
OS   Amazona aestiva (Blue-fronted Amazon parrot).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX   NCBI_TaxID=12930 {ECO:0000313|EMBL:KQL60504.1, ECO:0000313|Proteomes:UP000051836};
RN   [1] {ECO:0000313|EMBL:KQL60504.1, ECO:0000313|Proteomes:UP000051836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FVVF132 {ECO:0000313|EMBL:KQL60504.1};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Synapse, synaptosome {ECO:0000256|ARBA:ARBA00034102}.
CC   -!- SIMILARITY: Belongs to the SMAUG family.
CC       {ECO:0000256|ARBA:ARBA00008232}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQL60504.1}.
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DR   EMBL; LMAW01000137; KQL60504.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0Q3U3L9; -.
DR   STRING; 12930.A0A0Q3U3L9; -.
DR   Proteomes; UP000051836; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043005; C:neuron projection; IEA:UniProtKB-KW.
DR   GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0030371; F:translation repressor activity; IEA:InterPro.
DR   GO; GO:0043488; P:regulation of mRNA stability; IEA:InterPro.
DR   CDD; cd09557; SAM_Smaug; 1.
DR   Gene3D; 1.25.40.170; Smaug, PHAT domain; 2.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR037093; PHAT_dom_sf.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR037634; Smaug_SAM.
DR   PANTHER; PTHR12515:SF8; PROTEIN SMAUG HOMOLOG 1; 1.
DR   PANTHER; PTHR12515; STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED; 1.
DR   Pfam; PF00536; SAM_1; 1.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Synapse {ECO:0000256|ARBA:ARBA00022599};
KW   Synaptosome {ECO:0000256|ARBA:ARBA00022599};
KW   Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT   DOMAIN          320..383
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|SMART:SM00454"
FT   REGION          238..257
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          278..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          418..480
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          559..592
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        288..320
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        438..453
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   705 AA;  77944 MW;  FABA613E76B18145 CRC64;
     MMFRDQVGVL AGWFKGWNEC EQTVALLSLL KRVSRTQARF LQLCLEHSLA DCTELHILEG
     EANNPGIINQ WQQESKDKVI SLLLTHLPLL KPGNIEAKVE YMKLLPKILA HSIEHNQHIE
     ESRQLLSYAL IHPATSLEDR SALAMWLNHL EDRTSGGFGS QSRGRSDSVD YGQTHYYHQR
     QNSDDKLNGW QNSRDSGISV SASSWQDKNL ACENGHLPLY SSSSVPTTIN TIGTSTSTIL
     SGQTHHSPLK RSVSLTPPMN VPNQPLGHGW MSHEDLRARG PQCIPSDHAP LSPQSSVASS
     GSGGSEHLED QPSARNTFQE EGSGMKDVPA WLKSLRLHKY AALFSQMTYE EMMALTECQL
     EAQNVTKGAR HKIVISIQKL KERQNLLKSL ERDILEGGNL RVPLQELHQM ILTPIKAYSS
     QNSSTEEHSR DADSHHPSSL IGSDSQGSDC KDSAAGGMQQ HHLPGCEGES GGAPLPEGDL
     PGQFTRVMGK VCTQLLVSRP DEENISSYLQ LIDKCLIHEA FTEIQKKRLL SWKQQVQKLF
     RSFPRKSLLE LSGYRQQRSR GFGQSNSLPT AGSAGAGLGR RNPRQFQIPS RNLPTARLGL
     LGPTGLLGTP QRSPAASPAI LKQGRQNLWF ANPGGSNSMP SRSHSSVQRT RSLPVHTSPQ
     TMLMFQQPEF QVPVTEPDIN NRLESLCLSM TEHALSDGVD RTSTI
//