ID A0A0Q3US41_AMAAE Unreviewed; 943 AA.
AC A0A0Q3US41;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Vascular cell adhesion protein 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=AAES_96359 {ECO:0000313|EMBL:KQK80194.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK80194.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK80194.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK80194.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK80194.1}.
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DR EMBL; LMAW01002543; KQK80194.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3US41; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0005178; F:integrin binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd15211; 7tmA_GPR88-like; 1.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR047012; ICAM_VCAM.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008424; Ig_C2-set.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR13771; INTERCELLULAR ADHESION MOLECULE; 1.
DR PANTHER; PTHR13771:SF14; VASCULAR CELL ADHESION PROTEIN 1; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR Pfam; PF05790; C2-set; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 2.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 902..923
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..302
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT DOMAIN 438..511
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 624..708
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 715..797
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 804..883
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 943 AA; 104122 MW; 380D124A365A267F CRC64;
MPNASSWSAS SPLLLLWEDS SGTRIFLSLL YAVLAISGTL SNVMVIYLVF SFKKLQTTSN
AFIVNGCAAD LSVCALWMPQ EAVLGLLPPN SSSLRSAEYR LLRGGLLGLG LTVSLASHLL
VAFNRYVLIT KLPSVYQALY QRRHTGCMIG LSWALALLLV PLLPGLWTPG SAQQPPLRQT
DGSSRYTALL LALAVLGQTA LLLHCYLGIV RRVRGSAKRV SVLNFHLLHQ LPFPAAPPPP
RRSQRRLSSV SVLLLCCVFL LGTQPLVWVS LLGFFLRPAP PALQAASWLL LCALSALNPL
LYTWRSEEFR RAARSMEFCS EMSSGCLESP PVLRQSQGRI KNAXTLQARA ASILMCPEAD
DVREERWHSE RNKNGIKCIV EMRYQVTMLP DILNTESHYR DDKLDVEYNC KFVSVLSVAV
KAFEMEIIPA NRIVKQVGET LRLTCNTTGC ASPSFSWRTQ MDNPLGGTVN NYRTYSTLTM
NPVSTVNSHD YLCTVFCGEK EKKEKKEKSV KVEIYSFPRD PVIEISPSSA AAEPVTVTCK
ILDVYPSHYL EVLLKKGDHI LHEKNFYEDE STNTENKTVT YSFNPTAEDI GKEITCVAKL
PIPNMDXEPK ERVTSEKLTA NFGPQNTVIT ASPGNWPMEG DTLNLTCVTE SNPPAQIVWT
KHLADESIQL LTKNNVLSIP DARFSDSGLY TCEATNVVTN KTQKAAVDIV IRDGPKNTVI
SVIPATPVKE GETVIMKCTS SGNPAPVISW KKKKSTGESE QIYTGATLTI KNIKSQDLGL
YECEAYNRFG KEEKDVKLLV QVPPQNITVL VYPSENVKEG ENITITCSAY SNPPSEMVLK
KLHQQKEIIL PSVNGTFILY NVTKNDTGRY LLDVFNEVGN NITVIEIAVV ERLEKPDQMI
PLVIAFSSVT AVAVPAVAIL IYVTRKAKIN GSYSLVKALG LKV
//
