ID A0A0Q3USU5_AMAAE Unreviewed; 670 AA.
AC A0A0Q3USU5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Peflin {ECO:0000256|ARBA:ARBA00041025};
DE AltName: Full=PEF protein with a long N-terminal hydrophobic domain {ECO:0000256|ARBA:ARBA00041490};
DE AltName: Full=Penta-EF hand domain-containing protein 1 {ECO:0000256|ARBA:ARBA00042606};
GN ORFNames=AAES_80923 {ECO:0000313|EMBL:KQK81450.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQK81450.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQK81450.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQK81450.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, COPII-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00037873}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00037873}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQK81450.1}.
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DR EMBL; LMAW01002359; KQK81450.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3USU5; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048306; F:calcium-dependent protein binding; IEA:UniProt.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro.
DR CDD; cd16184; EFh_PEF_peflin; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR008077; GPCR_2_brain_angio_inhib.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR PANTHER; PTHR46212; PEFLIN; 1.
DR PANTHER; PTHR46212:SF3; PEFLIN; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13405; EF-hand_6; 1.
DR PRINTS; PR01694; BAIPRECURSOR.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 500..535
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 567..602
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 149..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 245..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 73991 MW; ADD1DB0368BC49CF CRC64;
MLVGIIVFNK LMSRDGISDK SKKQRAGASL WSSCVVLPLL ALTWMSAVLA MTDRRSILFQ
VLFAVFNSVQ GFVIITVHGF LRREVQDVVK CQMGGCRSEE NENSPDSCKN GQVQILTLKR
TLTWRVRQEV NTCNPATITG TLSRISLDGD EDPKLNTTSE GGLGFSSLPG NIPPSSILVQ
VPKMTPNVVA GLGELGDTPT QQLSLEAPGP VYLCTESSLR PLEXGWLRAP EPPRESDYMM
LPRRTSSLKP FPRDESTEEG VPGGTXRPAA EGDAYPSFVA VDHVNVNLNQ PYGTVKAPYG
LQFKQHPTVR QILASELSER SRTMPRTVPG SAMKVGSLER KRLRYSDLDF EKVMHTRKRH
SELYHELNQK FHTLXRYRAP AAGSSKREKR WSVSSGGGEK SMANDAASTK EQQLQAPAAP
PKPWSTFKAM TLGSLPSAQW DRLELRCADW GGPCAGLDVA DGDFQTEVLG SRGRAAPGAA
RAPPEGGGEG GGAPGNXLPG VDPEAFSWFQ AVDADHXGYI SVKELKQALV NSNWSTFNDE
TCLLMINMFD RTRSGRIDVY GFSALLRFIQ QWKNLFQQYD RDQSGSISFS ELQQAFSQMG
YNLSPQFSQL LLARYAQRSP SPSIQLDRFI QICMQLQSTT DAFREKDTGL VGNVRLSYED
FLTMVVTRML
//
