ID A0A0Q3WDJ2_BRECH Unreviewed; 1997 AA.
AC A0A0Q3WDJ2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=AN963_17995 {ECO:0000313|EMBL:KQL46794.1};
OS Brevibacillus choshinensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=54911 {ECO:0000313|EMBL:KQL46794.1, ECO:0000313|Proteomes:UP000051063};
RN [1] {ECO:0000313|EMBL:KQL46794.1, ECO:0000313|Proteomes:UP000051063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 8552 {ECO:0000313|EMBL:KQL46794.1,
RC ECO:0000313|Proteomes:UP000051063};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Lan J., Che J., Ge C.,
RA Shi H., Pan Z., Liu X.;
RT "Genome sequencing project for genomic taxonomy and phylogenomics of
RT Bacillus-like bacteria.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQL46794.1}.
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DR EMBL; LJJB01000010; KQL46794.1; -; Genomic_DNA.
DR RefSeq; WP_055745892.1; NZ_LJJB01000010.1.
DR STRING; 54911.AN963_17995; -.
DR PATRIC; fig|54911.3.peg.1637; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000051063; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:KQL46794.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:KQL46794.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 10..273
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1855..1989
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 1997 AA; 228181 MW; 058B028FE1F1F5D6 CRC64;
MSGKLLVPGY RITEFVSNHV NMGVYRAFRI VDNLPVIIKT QQKGIPRNDS IWKLKHEYRI
LESIQSEAVE AIVELVHNDR ETLLITEDHG GLPLSLLMKM RELSIREILT IALGVAHAMK
KVHQSRVVHK DINPANILVH PDTFDVKLIN FGLSTRLYQE YQSAMNPKEW QGNLRYVSPE
QTGRMNRTVD YRSDFYSFGI SLYEMLTGRP PFLSTDALEL VHAHMARKPV PPNQSHPSIP
AVLSDLVLKC LSKNVEDRYL SSSGLIADLE KCLDLLQVDG SINPFPLGIQ DRTNQLHISE
KLYGREQELV LLTESFEQIS NGATRLVMLS GNAGVGKSAL VREAQKAFLQ GKGRFISGKF
DQYKQSVPYS AILLAFQDLI RQILTGNERE LHMWSETILE ALQGLGQVIV DVIPQLEMII
GKQPVVPELP ATEAKNRFQM VMQRFVRIWA KPEHPLVLFL DDLQWADPSS LFLIQEMISD
LQVSHFLLLC AYREQEGSLM NPLMSALIEL GSQNRILRQI SLHPLEVDEI AQLLADTIQA
VPESTQPLAL IVHRKTAGNP FFTRQFLKSL YDKGLMKYVT DPGDWIWSLE EIEKLDTADN
VADFLVERMR LLPMLTQKLL AYAACLGNHF YLHMVAKARN QKESETIRHI WPAVEEGLLY
PLEGDSYLAY AALEEEDAAI HMKVHFTFLH DRIQQAAYSL LSEVEREMVH LKLGRMMREL
THSYESELLF EICNHMYQGA ELIDDHTERM HVGHCHLLAG QRAKLSTAFD AALRFFRQGT
EVLREEGWEL NRQLAVELYT MRAEAEYLCN NFDTAESLFA LVKQYAQTNA EQVRILEIQV
HMYTSLAKFP LVVDIANQAL QLLGVSIPNK PGKLDIIKEM WQIKRKLKGR KADELLYMPN
VPDENYRMAM NIISYAGPSS YFVDMNWFAL TILRVLHLSL VHGNDVASAN GYTGYGIVQA
AQFGKYQEGY DYGLLACSVA DSFHDPIAMT KAYGAFAIMI NHWRDHAKTN IPLLKKAIQH
GLESGGNIYV AYNAHGLLEA MLYCGSPIDE LRQQIGLYAD LIRQLKVVDH DDRLLLLKQA
LHCFTRTEAG DPTAFCEENF DEEAYVKGLQ TDGTNYKRYM YHYYKSMVHF LFGNYREAAE
MTTEAEQWME TVSGQILVSE HVFIQTLALT GLYPQASWAD KRKYAKKIKS NLSKMKKWAT
HCVENFHHKY LLMRAEWIRV SGDPQAATPF YEQAIQSAKK YGFLQKEAIA YELAAKHYLS
MGMETVSTFY LSEAHFGYMQ WGAVAKAQAI EAQNHFSTER IGSHQAITDI TVTGHTPDMV
DLMTVIKASQ MIASEIKLDK LLATMLRTVM SNAGAQRGFI ILKNESEWFI EAAGSIDEDI
EILQSIPYEQ GSLLSVATVN YVMRTEEILV LHEAYVEAIF FKDPYITKNM PKSILCAPLW
QQGKMVGVVY LENNESTHVF NEGRTELLRL LFSQIATFIE NARLYHQLEQ WNQSLEKIVA
ERTDKIETLL RANKNLLNNA GQGFLSFCRN LLIHSEYSQE CVRMFGRELA GLSIPELLYP
DSKEDQVFIE SLLNKYFELE NGAQRELYLS LFPTEIMVNH LPLKVECKPI DEGSGEYSGG
LMLILTDLSE QRALENKVEQ EWQSLKMVVT VAISLDLFET VLQSFRSFVT SEWKHIWAEK
GEGAEKLYQL ISRLHQFKGD FSQFYLIHTP AQLHEMESIL VHLAKNKVIA PDVEREIQSG
IDSICSAIQQ DLEIVKQQLG TDFLEKKEKA VSFSKDRWNA FSGQLTTYLQ GEGQEHLLHE
FSRLRNRPFT ELLSRYDEYM AKVSARLDKR IYPLQIDAED VWVDPQRFGN FVSCLVHVFS
NALDHGIEDE VERVAQQKER WGTIRCQIKQ EGSMLHLTIS DDGKGVDLER LKMVGQEKGW
DDTKSEQEWL NELFKEDVST KIEVASELSG RGVGLSIVKR EVERLGGTVD ISTQKGKGTR
FHFRIPLKEE ESYLRHV
//
