ID A0A0Q3WU25_AMAAE Unreviewed; 505 AA.
AC A0A0Q3WU25;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Solute carrier family 41 member {ECO:0000256|RuleBase:RU369007};
GN ORFNames=AAES_31377 {ECO:0000313|EMBL:KQL51979.1};
OS Amazona aestiva (Blue-fronted Amazon parrot).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX NCBI_TaxID=12930 {ECO:0000313|EMBL:KQL51979.1, ECO:0000313|Proteomes:UP000051836};
RN [1] {ECO:0000313|EMBL:KQL51979.1, ECO:0000313|Proteomes:UP000051836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FVVF132 {ECO:0000313|EMBL:KQL51979.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a magnesium transporter.
CC {ECO:0000256|RuleBase:RU369007}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU369007}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU369007}.
CC -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC {ECO:0000256|ARBA:ARBA00009749, ECO:0000256|RuleBase:RU369007}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQL51979.1}.
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DR EMBL; LMAW01000447; KQL51979.1; -; Genomic_DNA.
DR STRING; 12930.A0A0Q3WU25; -.
DR Proteomes; UP000051836; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022890; F:inorganic cation transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030001; P:metal ion transport; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 2.
DR InterPro; IPR006667; SLC41_membr_dom.
DR InterPro; IPR036739; SLC41_membr_dom_sf.
DR InterPro; IPR045349; SLC41A1-3.
DR PANTHER; PTHR16228; DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41; 1.
DR PANTHER; PTHR16228:SF23; SOLUTE CARRIER FAMILY 41 MEMBER 1; 1.
DR Pfam; PF01769; MgtE; 2.
DR SUPFAM; SSF161093; MgtE membrane domain-like; 2.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU369007};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|RuleBase:RU369007};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU369007};
KW Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU369007};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU369007};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU369007}.
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369007"
FT TRANSMEM 182..204
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369007"
FT TRANSMEM 216..243
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369007"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369007"
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369007"
FT TRANSMEM 319..339
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369007"
FT TRANSMEM 401..419
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369007"
FT TRANSMEM 431..451
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369007"
FT TRANSMEM 471..496
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369007"
FT DOMAIN 141..275
FT /note="SLC41A/MgtE integral membrane"
FT /evidence="ECO:0000259|Pfam:PF01769"
FT DOMAIN 355..487
FT /note="SLC41A/MgtE integral membrane"
FT /evidence="ECO:0000259|Pfam:PF01769"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 63..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 54008 MW; D3246A98D564929C CRC64;
MSSKPEQKET HQANGAALPI VPVDCLASPE RGQLVEPSDF LGPDGAGVEV VVLESRANAK
GVREEDALLE NGSQSNESDD TSTDRGPEPA SPLKETSFSI GLQVLFPFLL AGFGTVAAGM
VLDIVQHWDV FKYVTEVFIL VPALLGLKGN LEMTLASRLS TAANIGQMDT PKELWKMITG
NMALIQVQAT VVGFLASIAA VVFGWIPDGH FSIDHAVLLC ASSVATAFIA SLVLGMIMIG
VIIGSRKMGI NPDNVATPIA ASLGDLITLA LLSGISWGLY KELESKAYVN PLVCAFFIAL
LPIWIIIAKK NAATREVLYS GWEPVIIAMA ISSVGGLILD RTVSDPNFAG MAVFTPVING
VGGNLVAVQA SRISTYLHMS GMPGELPCTT FFSSDVNSRS ARVLFLLVVP GHLVFLYTIS
SMQGGHTTLT LIFXVFYMTA ALLQVLILLY IADWMVHWMW GRDLDPDNFS IPYLTALGDL
IGTGLLALSF HVLWLIGDRD SDVGD
//
