ID   A0A0Q3WU78_AMAAE        Unreviewed;       205 AA.
AC   A0A0Q3WU78;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   22-FEB-2023, entry version 18.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 20 {ECO:0000256|ARBA:ARBA00019690, ECO:0000256|RuleBase:RU364152};
DE   AltName: Full=Mediator complex subunit 20 {ECO:0000256|RuleBase:RU364152};
GN   Name=MED20 {ECO:0000256|RuleBase:RU364152};
GN   ORFNames=AAES_31962 {ECO:0000313|EMBL:KQL52036.1};
OS   Amazona aestiva (Blue-fronted Amazon parrot).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Amazona.
OX   NCBI_TaxID=12930 {ECO:0000313|EMBL:KQL52036.1, ECO:0000313|Proteomes:UP000051836};
RN   [1] {ECO:0000313|EMBL:KQL52036.1, ECO:0000313|Proteomes:UP000051836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FVVF132 {ECO:0000313|EMBL:KQL52036.1};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator involved in
CC       the regulated transcription of nearly all RNA polymerase II-dependent
CC       genes. Mediator functions as a bridge to convey information from gene-
CC       specific regulatory proteins to the basal RNA polymerase II
CC       transcription machinery. Mediator is recruited to promoters by direct
CC       interactions with regulatory proteins and serves as a scaffold for the
CC       assembly of a functional preinitiation complex with RNA polymerase II
CC       and the general transcription factors. {ECO:0000256|ARBA:ARBA00025687,
CC       ECO:0000256|RuleBase:RU364152}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364152}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU364152}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 20 family.
CC       {ECO:0000256|ARBA:ARBA00010743, ECO:0000256|RuleBase:RU364152}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQL52036.1}.
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DR   EMBL; LMAW01000447; KQL52036.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0Q3WU78; -.
DR   STRING; 12930.A0A0Q3WU78; -.
DR   Proteomes; UP000051836; Unassembled WGS sequence.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR013921; Mediator_Med20.
DR   PANTHER; PTHR12465:SF0; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20; 1.
DR   PANTHER; PTHR12465; UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49; 1.
DR   Pfam; PF08612; Med20; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364152};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364152};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051836};
KW   Transcription {ECO:0000256|RuleBase:RU364152};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364152}.
SQ   SEQUENCE   205 AA;  22935 MW;  FB4D1E02201B977C CRC64;
     MRRDSRASTV QQTVERLTRK LEVLGAEKQG TFCVDCETYH TAASTIGTQG QTGKLMYVMH
     NSEYPLSCFA LFESGPCLIA DANFDILMVK LKGFFQNAKA NKIETRGTRY QYCDFLVKVG
     TVTMGPSARG ISVEVEYCPC VIANDCWSLL MEFMQSFMGS HAPGLPSVFG TKHDSIYSPS
     DTMVQYMELF NKIRKQQQVP VAGMR
//