ID A0A0Q3X1G1_9BACI Unreviewed; 327 AA.
AC A0A0Q3X1G1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=2-oxoisovalerate dehydrogenase {ECO:0000313|EMBL:KQL55554.1};
GN ORFNames=AN964_17705 {ECO:0000313|EMBL:KQL55554.1};
OS Heyndrickxia shackletonii.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Heyndrickxia.
OX NCBI_TaxID=157838 {ECO:0000313|EMBL:KQL55554.1, ECO:0000313|Proteomes:UP000051888};
RN [1] {ECO:0000313|EMBL:KQL55554.1, ECO:0000313|Proteomes:UP000051888}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 18435 {ECO:0000313|EMBL:KQL55554.1,
RC ECO:0000313|Proteomes:UP000051888};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Lan J., Che J., Ge C.,
RA Shi H., Pan Z., Liu X.;
RT "Genome sequencing project for genomic taxonomy and phylogenomics of
RT Bacillus-like bacteria.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQL55554.1}.
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DR EMBL; LJJC01000004; KQL55554.1; -; Genomic_DNA.
DR RefSeq; WP_055741284.1; NZ_LJJC01000004.1.
DR AlphaFoldDB; A0A0Q3X1G1; -.
DR STRING; 157838.AN964_17705; -.
DR PATRIC; fig|157838.3.peg.3925; -.
DR OrthoDB; 9771835at2; -.
DR Proteomes; UP000051888; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000051888}.
FT DOMAIN 6..181
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 327 AA; 36070 MW; F90EF01B70509AB2 CRC64;
MKTQKLSLVQ AVTDGLQTMM RERKEIIVMG EDVGRNGGVF RATDGLVDEF GEERVIDTPL
SEAGIIGTAI GLAINGFLPV AEIQFLGFIY PAFEQIMTHA TRIRMRTMSK FHVPLVIRAP
YGAGVKAPEI HSDSMEALFT HMPGIKVVCP SNPYDAKGLL ISSIEDPDPV LFLESLRSYR
AFKEEVPTGK YTVEIGKANL LMEGEDITII AWGAMVPVAM KAAEKAKDEG IGCDVIDLRT
LYPLDHEQIS ESVQKTGRVV IVHEAHVTSG LGAEIISVIQ ETSFLYLRAP IERVAGFDVP
VPFYSLENHF LPNEGRITRA IEKVMHF
//
