ID A0A0Q4GYH8_9SPHI Unreviewed; 600 AA.
AC A0A0Q4GYH8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN ORFNames=ASE74_15535 {ECO:0000313|EMBL:KQM78118.1};
OS Pedobacter sp. Leaf216.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=1735684 {ECO:0000313|EMBL:KQM78118.1, ECO:0000313|Proteomes:UP000051744};
RN [1] {ECO:0000313|Proteomes:UP000051744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf216 {ECO:0000313|Proteomes:UP000051744};
RA Garrido-Oter R., Mueller D.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000051744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf216 {ECO:0000313|Proteomes:UP000051744};
RA Vorholt J.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQM78118.1}.
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DR EMBL; LMKM01000005; KQM78118.1; -; Genomic_DNA.
DR RefSeq; WP_055904631.1; NZ_LMKM01000005.1.
DR AlphaFoldDB; A0A0Q4GYH8; -.
DR STRING; 1735684.ASE74_15535; -.
DR OrthoDB; 9801077at2; -.
DR Proteomes; UP000051744; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..600
FT /note="Beta-glucuronidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006219604"
FT DOMAIN 35..211
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 215..304
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 306..547
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 600 AA; 69349 MW; 23E70F5B947076B8 CRC64;
MLKTTYSVFL ICFSLLSSIS YGQVTAIQNI QARKIQSLNG KWNYIVDPYE NGYYDYRHEP
FDQSKTGTGG YFDDKVQKDK SELIEYDFDH SPQMNVPGDW NSQSEKLELY EGNVWLRKKF
DAKPEKGKRY FVYFAAVNYE AHVYLNGKKL GVHKGGFTPF QFDVTSNLKV GENSIVLKVD
NIRKQDEIPT VNTDWWNYGG ITRDVFLAEF PDHFINDYKL QLAKGNKNLL NFSVKLADAT
AGQEITLSIP ELKLEKKYKT DSEGKIADEF TWNNLSLWSP ETPKLYAVNI KTDKENINDK
IGFRTIQVDG DSILLNGKSV FLRGISLHDE NPLLAGRLRS EGDMRMMLQW AKDMNCNYVR
LAHYPHNEEM IRLADEMGLL VWAEVPVYWT ISWTNPATYA NAKQQLTDLI VRDKNRASVI
VWSIGNETPL SDARLSFMSN LAETARTFDD TRLVAAALEV HREGNNIILN DPLGEKIDLV
SFNEYAGWYW GGNPSEITKY NFDIKYKKPV VITEFGGDAL GGFHADENTR WSEEYQEALY
KNQITMLSKI GALRGMTPWI LTDFRSPRRQ HPIYQNFWNR KGLIFYVLKD FYDQMQVKYK
//
