ID   A0A0Q4KVM9_9SPHN        Unreviewed;       944 AA.
AC   A0A0Q4KVM9;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Peptidase M16 {ECO:0000313|EMBL:KQN26755.1};
GN   ORFNames=ASE86_00950 {ECO:0000313|EMBL:KQN26755.1};
OS   Sphingomonas sp. Leaf33.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1736215 {ECO:0000313|EMBL:KQN26755.1, ECO:0000313|Proteomes:UP000051455};
RN   [1] {ECO:0000313|EMBL:KQN26755.1, ECO:0000313|Proteomes:UP000051455}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf33 {ECO:0000313|EMBL:KQN26755.1,
RC   ECO:0000313|Proteomes:UP000051455};
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KQN26755.1, ECO:0000313|Proteomes:UP000051455}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf33 {ECO:0000313|EMBL:KQN26755.1,
RC   ECO:0000313|Proteomes:UP000051455};
RA   Schulze-Lefert P.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQN26755.1}.
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DR   EMBL; LMLB01000001; KQN26755.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0Q4KVM9; -.
DR   STRING; 1736215.ASE86_00950; -.
DR   Proteomes; UP000051455; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 3.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 3.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051455};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          61..174
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          211..296
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          689..865
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   944 AA;  99973 MW;  F66CF3E568501ACA CRC64;
     MPAQQAPQPA AATVQAPAVA VDRSAWLYKG SDITPDPDWR FGTLPNGLRY AVRKNGVPPG
     QVSIRVRMDV GSLHERDSER GFAHLIEHLS FRGSEHVPDG EAKRIWQRMG VTFGADTNAS
     TSFTQTVYKL DLPMANQTGL DESLKILSGM MAGPSLTQTA LDAERPVVLS EAREQPGPQV
     RLGDATREVF FAGQPLADRS PIGTTETLSS ATAAAVTAFH DRWYRPERAI VVVSGDMDPA
     LFEAAIVKHF ADWRGNGAAV PAPDFGTPKP AKTDTAALVE PQLPTLVSLA WLRPWTVGDD
     TVIFNQKRMI DMVAVRIVNR RLESRARGGG SFISAGANLE DISRSANATL MNILPLGNDW
     QTALKDVRTG IADAIATPPT QGEIDRELTD IQTSMKASVA QASVEAGAKK ADDLVDAVDI
     KETTTTAQTS LGILQDAIAK KMFTPAAVQA SAKAVFSGVA LRGVVNTPQP SENAAAALQA
     ALTAEMKPGV AANSKLAAIG FDALPKLGAP GKVVARSIAV TDPKMEKVTF ANGVNLLLFE
     NPSEASRVYV RVRFGRGLAG LPADRQTPVY AGDLALVASG IGKLGQEEID RITTGRRIAL
     DFAVDEDAFL FGATTSAEDL ADQLKLIAAK LSTPGWDPNP VARAKAVMLA GYASQAASPD
     GVLARDLDRL LHDGDPRWGT PSRADLEKLD ARSFRAFWEP ILASGPIEVQ IYGDMKSDAA
     IAAVASSLGA LKPRKDAPVA TAPIRFPAPT TTPVTRTHDG RDTQAAAVIA WPTGGGSDGI
     ATGRKLEVLA AVFRDRLLDK LRSSAGISYT PNVASNWPVG LSGGGRIMAI GSVPPDKTGY
     FFDLSREIAA DLVARPVDAD ELRRALVPVV QFVARLSTGN QFWLMQTEGG STDPKRLAAL
     NTIATDLTTI TPSELQALAA QYLVPAKAWT MTVLPKDGAA GAAK
//