ID   A0A0Q4RUX2_9BURK        Unreviewed;       884 AA.
AC   A0A0Q4RUX2;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ASF16_05775 {ECO:0000313|EMBL:KQO19494.1};
OS   Acidovorax sp. Leaf78.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Acidovorax.
OX   NCBI_TaxID=1736237 {ECO:0000313|EMBL:KQO19494.1, ECO:0000313|Proteomes:UP000051234};
RN   [1] {ECO:0000313|Proteomes:UP000051234}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf78 {ECO:0000313|Proteomes:UP000051234};
RA   Garrido-Oter R., Mueller D.B.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000051234}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Leaf78 {ECO:0000313|Proteomes:UP000051234};
RA   Vorholt J.;
RT   "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KQO19494.1}.
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DR   EMBL; LMLZ01000020; KQO19494.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0Q4RUX2; -.
DR   STRING; 1736237.ASF16_05775; -.
DR   OrthoDB; 8929028at2; -.
DR   Proteomes; UP000051234; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 2.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   CDD; cd12915; PDC2_DGC_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 5.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF13426; PAS_9; 3.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 3.
DR   SMART; SM00091; PAS; 3.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 2.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        308..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          346..391
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          418..468
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          540..592
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          745..877
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   884 AA;  97124 MW;  9184EDB5CC014A9F CRC64;
     MTVWVPFRMH LNSTTPVSQA EQQRRKLGAL LVGGNLLLGA VLAGLVLSVM SSSRQAHEDR
     ARAAAERFVA IASASLQSEL GAVDTALKIT MDDLQRAGFD AGASVQDIND HLAAKHRVLA
     GVEGFRVADE NGLVRWGNLI DSASPPDITN RDFFFRARDS SSDKAVVSDP VISRVSGHSV
     IVVARPMAWG GKFRGVLYAS IHTEHFEQIF KRYELADHDG ISLRTNDLKL VALQSPRGRS
     TAAVGTRDVA QELQDSLRSK PSAGSYLATS KVDGISRTFA YRQVDGWPLL AIAGLDNSNR
     WSQWRREMLM VSLLAGLAWA LSCAATIAVY RFGRREIRAV AALQAQSRQT QTLLRVAGDG
     IHILDRAGRL VELSDSFAEM HGSSRDKLQG QHVASWDANQ NEARIDAWLA KIRDGDKQRV
     EVQHVRADGS IIDVDLHWRA VDIDGHLLIF GSARDITDKK HLLQSLEESS ARIQDLYDHA
     PCGYFSLDAD GRFVHLNATA KAWFGGDFQS DRQFVGLLDD ATLPQFRDHF IALALQLHAP
     EIEVCISPAN APQRHLCINS TAVRDAQGNF LMSRTVAVDI TAQREAQQRV ESLLREQSAM
     LNSDVVGMVK FHHGKVSWKN RAFEKMLGYE DGELAGAAIE TLCAEDGERH ALAQKTLLAM
     RRGENYRDDV RLKQKQGTTI WVDLNGVQLS GTESFWMAVD ITEAKRAHEQ ITHVAFHDAL
     TQLPNRLLLL DRMQQALAGA ERFGHEVAVC FLDLDGFKEV NDQYGHEAGD KLLVAIAARI
     SACIRATDTA ARLGGDEFVL LLAPLAGDEW RVIVDRLMQT VDAPVPLAAG LKVTLGMSIG
     VALSRGRTQA EVLVAEADEA MLHAKRRGKG RIHLAGSAQF VTRP
//