ID A0A0Q4UXF5_9MICO Unreviewed; 415 AA.
AC A0A0Q4UXF5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:KQO64938.1};
GN ORFNames=ASF23_01895 {ECO:0000313|EMBL:KQO64938.1};
OS Curtobacterium sp. Leaf261.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Curtobacterium.
OX NCBI_TaxID=1736311 {ECO:0000313|EMBL:KQO64938.1, ECO:0000313|Proteomes:UP000050821};
RN [1] {ECO:0000313|EMBL:KQO64938.1, ECO:0000313|Proteomes:UP000050821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf261 {ECO:0000313|EMBL:KQO64938.1,
RC ECO:0000313|Proteomes:UP000050821};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KQO64938.1, ECO:0000313|Proteomes:UP000050821}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Leaf261 {ECO:0000313|EMBL:KQO64938.1,
RC ECO:0000313|Proteomes:UP000050821};
RA Schulze-Lefert P.;
RT "Functional overlap of the Arabidopsis leaf and root microbiotas.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KQO64938.1}.
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DR EMBL; LMMJ01000001; KQO64938.1; -; Genomic_DNA.
DR RefSeq; WP_055948085.1; NZ_LMMJ01000001.1.
DR AlphaFoldDB; A0A0Q4UXF5; -.
DR STRING; 1736311.ASF23_01895; -.
DR OrthoDB; 1402717at2; -.
DR Proteomes; UP000050821; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF2; 3-OXOADIPYL-COA_3-OXO-5,6-DEHYDROSUBERYL-COA THIOLASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000050821};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:KQO64938.1}.
FT DOMAIN 7..257
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 269..390
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 95
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 347
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 378
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 415 AA; 43126 MW; EF2CD228B65A217D CRC64;
MTKASDVVFV DGVRTPFGRA GEKGVFWNTR ADDLATHAMR GLLDRNASLD GAAVDDVAVA
ATTQQGDQGL TLGRTVGMLA GLPSSVPGYA IDRMCAGAMT SVTTLAGAIA FGAADVAIAG
GVEHMGRHPM GFGADPNPRF LAERMVAGDA LVMGNTAERL HDRFPAITKD RTDAFAVRSQ
QRYQAAWEAG KHQPDIIPVA TATDSGWDVI DSDEPPRPGT TLEGLAALKT PFRSHGRVTA
GNAAGLNDGS TMALLASTAG AAQHGLGVKM RMVSFAFAGV DPEVMGVGPV PATDKALAKA
GLTIDDIGLF EINEAFAVQV LAFLDNYGIP EDSTDVNPWG GAIAVGHPLA SSGVRLMSQL
AAEFAERPDV EYGITTMCIG LGQGGTVIWE NPHYSRSAAR AARSVRPARS SRKAA
//
